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Murder accused stabbed pub landlord 11 times after he was barred – Liverpool Echo

Posted: February 11, 2020 at 5:42 pm

A man accused of murdering a pub landlord allegedly told police: "You don't need any evidence, I stabbed him to f***."

Lee Abbott knifed dad-of-three Christian Thornton 11 times, after he barred him from the Hammer & Pincers in Widnes.

He stabbed the 49-year-old in the heart and lungs outside the Liverpool Road pub on Sunday, August 11 last year.

Abbott, 35, of Rose Street, Widnes, admits manslaughter but denies murder, in a trial at Liverpool Crown Court.

Jurors today heard Mr Thornton had barred Abbott, then reported him to the police for threatening to burn down his pub.

The landlord later made a report to Widnes PubWatch, which voted to ban Abbott from every pub in the area for a year.

Abbott was informed by letter and went to the Hammer and Pincers at around 3.15pm, armed with a knife in a rucksack.

Opening the trial, David McLachlan, QC, prosecuting, said Mr Thornton, who was practising darts, pushed Abbott outside.

Witnesses described the dad saying "no, get out, you're barred" and telling "very aggravated" Abbott: "Calm down, Lee, go home."

They said Abbott asked "Why am I barred? What have I done?" before pushing him and saying: "You know I would've protected you."

Mr McLachlan said CCTV footage showed Mr Thornton ringing 999 and showing Abbott, who walked away, but then ran at him.

One woman said Mr Thornton shouted "get back" but Abbott pulled out "a f***ing huge kitchen knife" and lunged at him.

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A man, who was stood outside, said: "There was no stopping him, he just ran like a mad man.

"He pulled his knife out and stabbed him three, two or three times, turned fell, got up and then fled."

Mr Thornton collapsed and neither paramedics nor a doctor who arrived by helicopter could save his life.

Armed police arrested Abbott when he came out of a friend's house in Ardern, Widnes at 4.22pm, wearing just his boxer shorts.

Mr McLachlan said he told officers "I attacked that Chris, yeah" and added: "You don't need any evidence, I stabbed him to f***."

He said Abbott was taken into custody and said "I've f***ed up here, I know that", then "I'm not a bad person, I've been put in a bad situation."

During police interviews, Abbott said he never had a problem with Mr Thornton, but then described an incident a month beforehand.

Mr McLachlan said Abbott explained he was with a group of men on a ramp outside the pub who were "a bit loud" and "a bit intimidating".

Abbott said he didn't know whether they upset regulars, but Thornton asked them to leave, so he said: "Right, no problem, we'll go."

CCTV showed him speaking to Mr Thornton at the pub on August 2, when they shook hands and the landlord told him he was barred.

The next day, Abbott was filmed "putting his fingers up" to a camera, then "head to head" with Mr Thornton in the beer garden, when Mr McLachlan said he threatened to burn the pub down.

However, when Mr Thornton reported him to police, he said he didn't want any formal action being taken against him, but for the incident to be logged and officers to tell him he was barred.

Two days after a Widnes PubWatch meeting on August 6, Halton Council wrote to Abbott to inform him of the 12-month ban.

On August 11, Abbott caught a taxi from his girlfriend Danielle Hayes' home to Liverpool Road, carrying his rucksack by hand as he entered the pub.

Abbott told police he tried to explain to Mr Thornton he got the group to leave in the prior incident, but the landlord "wasn't having any of it" and it became "a little bit heated".

He said when Mr Thornton got his phone out and rang 999, he ran back towards him and started stabbing him.

Abbott said: "I just panicked I didnt know what to do, I just, I just saw red and just lost it and I just... I just come down and I just pulled the knife, pulled the knife and just, and just, obviously what youve just seen on that, on, on the CCTV, I just, I just didn't, I just lost it completely."

He added: "It was so fast it was like red mist, I didn't know exactly, I couldn't recall exactly what had gone on."

Abbott accepted previously threatening Mr Thornton, saying he wouldn't have a pub if he carried on, because he was "p***ed off", which was "a daft thing to say".

However, he said he couldn't believe it when Mr Thornton tried to get him barred from every pub, which was "a bit personal".

Mr McLachlan said Abbott told police he was "really upset", had been drinking all day and was "angry".

He also said he suffered from depression and was taking testosterone replacement therapy because he had a blood disorder called haemochromatosis, which 'crashed' his hormones, and affected his mood and stability.

Police recovered the blade used to stab Mr Thornton at the scene, which had snapped in two, and the handle in Abbott's rucksack, at his friend's house.

He said he took both the knife and rucksack from his girlfriend's house because he was annoyed, and when asked why, replied: "I've no idea, I don't know what I was thinking."

Abbott accepted threatening to burn the pub down and said that when drinking: "It does send me, it sends me a little bit... a little bit nasty."

He said: "I just lost it by that point, completely lost it" and added: "I just stabbed him, I was in a, just a rage, I wasn't in control... it's scary."

However, he said: "I just saw red... obviously knew I was gonna hurt him, I knew I was gonna stab him I didn't think for one minute 'I want to kill him'."

Tests revealed Abbott was an estimated three and a half times over the drink drive limit during the attack and had cocaine and testosterone in his system.

Mr McLachan said Abbott believed it was "an injustice" when he was barred, and armed himself with a knife because he intended to either kill or inflict really serious harm on the landlord.

He said: "And what did Lee Abbott do? He stabbed and he stabbed Christian Thornton to death in broad daylight on an early Sunday afternoon."

Mr McLachlan said prosecutors understood Abbott would argue it wasn't murder because he didn't have the necessary intent, due to being "heavily intoxicated", and would rely on the partial defence of diminished responsibility due to "an abnormality of mental functioning".

Mr McLachlan said: "We do not accept either of these defences and will assert that this is simply a case of murder.

"Murder pure and simple, where a man knows what he did, he took a knife to the scene, and he stabbed somebody 11 times."

(Proceeding)

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Murder accused stabbed pub landlord 11 times after he was barred - Liverpool Echo

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Testosterone Replacement Therapy Market is poised to achieve continuing growth During Forecast Period 2020-2026 – Jewish Life News

Posted: February 10, 2020 at 7:46 am

Global Marketers.biz has published an innovative statistics of the market titled as Testosterone Replacement Therapy Market. To clarify the various aspects, the analyst studies and elaborates the terms by using qualitative and quantitative research techniques. Finance teams can use a variety of corporate planning applications to fulfil the budgeting, planning & financial modelling, needs of their organization, whatever its size, industry and location.

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Graphs, tables, bar graphs and pie charts have been represented in sophisticate manner for the clients to better understand the analysis. To enlarge the businesses, customers get increased rapidly through Testosterone Replacement Therapy industry techniques.

Leading Establishments (Key Companies): AbbVieEndo InternationalEli lillyPfizerActavis (Allergan)BayerNovartisTevaMylanUpsher-SmithFerring PharmaceuticalsKyowa KirinAcerus Pharmaceuticals

Different regions, such as Americas, United States, Canada, Mexico, Brazil, APAC, China, Japan, Korea, Southeast Asia, India, Australia, Europe, Germany, France, UK, Italy, Russia, Spain, Middle East & Africa, Egypt, South Africa, Israel, Turkey and GCC Countries are focused to give the summarized data about the production of Testosterone Replacement Therapy market.

The global Testosterone Replacement Therapy Market is served as a backbone for the enlargement of the enterprises. To address the challenges, the report examines different key factors such as drivers and opportunities. Restraints are considered for evaluation of risk in market.

Segments covered in the report

This report forecasts revenue growth at a global, regional & country level, and analyses the market trends in each of the sub-segments from 2015 to 2026. For the purpose of this study, Global Marketers.biz have segmented the Testosterone Replacement Therapy market on the basis of type, end-user and region:

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Type Outlook (Revenue in Million USD; 20152026)

GelsInjectionsPatchesOther

End Use Outlook (Revenue in Million USD; 20152026)

HospitalsClinicsOthers

Testosterone Replacement Therapy Market Summary: This report includes the estimation of market size for value (million US$) and volume. Estimation methodology validate the market size of Testosterone Replacement Therapy industry, to estimate the size of various other dependent submarkets in the overall market. Secondary research is used to identify the top players in the market, and their market shares have been determined through primary and secondary research. Each type is studied based on classification as Sales, Testosterone Replacement Therapy Market Share (%), Revenue (Million USD), Price and Gross Margin.

Report Objectives:

Target Audience:

Table of Content:

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The Global Endocrinology Drugs Market is expected to grow by USD 24.78 bn during 2020-2024, progressing at a CAGR of 7% during the forecast period -…

Posted: February 9, 2020 at 5:44 pm

Global Endocrinology Drugs Market 2020-2024 The analyst has been monitoring the global endocrinology drugs market and it is poised to grow by USD 24. 78 bn during 2020-2024, progressing at a CAGR of 7% during the forecast period.

New York, Feb. 04, 2020 (GLOBE NEWSWIRE) -- Reportlinker.com announces the release of the report "Global Endocrinology Drugs Market 2020-2024" - https://www.reportlinker.com/p03793964/?utm_source=GNW Our reports on global endocrinology drugs market provides a holistic analysis, market size and forecast, trends, growth drivers, and challenges, as well as vendor analysis covering around 25 vendors. The report offers an up-to-date analysis regarding the current global market scenario, latest trends and drivers, and the overall market environment. The market is driven by increase in incidence of endocrine disorders. In addition, association between obesity and endocrine disorders is anticipated to boost the growth of the global endocrinology drugs market as well.

Market Segmentation The global endocrinology drugs market is segmented as below: Therapy area Diabetes Drugs Thyroid Hormone Disorder Drugs HGH Testosterone Replacement Therapy Others

Geographic segmentation North America Europe Asia ROW

Key Trends for global endocrinology drugs market growth This study identifies association between obesity and endocrine disorders as the prime reasons driving the global endocrinology drugs market growth during the next few years. Prominent vendors in global endocrinology drugs market We provide a detailed analysis of around 25 vendors operating in the global endocrinology drugs market, including some of the vendors such as Abbott Laboratories, AbbVie Inc., AstraZeneca Plc, Eli Lilly and Co., GlaxoSmithKline Plc, Groupe Sanofi, Merck & Co. Inc., Novartis International AG, Novo Nordisk AS and Pfizer Inc. The study was conducted using an objective combination of primary and secondary information including inputs from key participants in the industry. The report contains a comprehensive market and vendor landscape in addition to an analysis of the key vendors.Read the full report: https://www.reportlinker.com/p03793964/?utm_source=GNW

About ReportlinkerReportLinker is an award-winning market research solution. Reportlinker finds and organizes the latest industry data so you get all the market research you need - instantly, in one place.

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The Global Endocrinology Drugs Market is expected to grow by USD 24.78 bn during 2020-2024, progressing at a CAGR of 7% during the forecast period -...

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Testosterone Replacement Therapy Market- Revenue, Research Till 2026 Industry Influence Over Market – Reporting 99

Posted: February 8, 2020 at 8:45 am

The goal of Global Testosterone Replacement Therapy market research report is to provide the users a complete picture of the Testosterone Replacement Therapy market during the forecast period from 2020-2026 The global Testosterone Replacement Therapy market report provides the key market insights and the growth-inducing factors. It also does the comprehensive study of Testosterone Replacement Therapy Industry based on market gains, market volume, key industry sections of Testosterone Replacement Therapy which are differentiated based on product type, product application, major geographical regions contributing to the development of Testosterone Replacement Therapy market.

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Global Testosterone Replacement Therapy Market Analysis By Major Players:

AbbviePfizerEli LillyTeva PharmaceuticalsMylanBayer Healthcare PharmaceuticalsAntares PharmaFerring PharmaceuticalsAllerganAntares PharmaSandozClarus TherapeuticsJuniper PharmaceuticalsEndo InternationalAcerus PharmaceuticalsForendo PharmaMetp PharmaRepros Therapeutics

Global Testosterone Replacement Therapy market enlists the vital market events like Testosterone Replacement Therapy product releases, technical developments and groundbreaking market schemes of Testosterone Replacement Therapy which will help the readers to identify opportunities and risk factors which affect the development. Worldwide Testosterone Replacement Therapy market report covers chief market segments based on product type, product application, potential users and key zones.

Advantages Of The Global Testosterone Replacement Therapy Market Report:

Extensive analysis based on market segments will enhance the Testosterone Replacement Therapy market growth

Analysis of Testosterone Replacement Therapy market key player and their business tactics will help in making important business decisions

Testosterone Replacement Therapy Market Technological advancements will fuel the growth of global market

Region-wise analysis and emerging segment analysis of Testosterone Replacement Therapy market will provide clear view of global market

Testimonials to companies will provide concrete and better control over the Testosterone Replacement Therapy market

This Testosterone Replacement Therapy report analyzes the global market by the following segments:

By Product Types:

GelsInjectablesPatchesOther

By Product Applications:

HospitalsClinicsOther

Analysis By Geographical Zones:

Europe (Germany, France, Italy, Russia and UK)

North (Canada, USA and Mexico)

Latin America (Middle and Africa)

Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria and South Africa)

Asia-Pacific (South-east Asia, China, India, Korea and Japan)

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Following 15 elements represents the Testosterone Replacement Therapy market globally:

Element 1, enlist the goal of global Testosterone Replacement Therapy market covering the market introduction, product image, market summary, development scope, Testosterone Replacement Therapy market presence;

Element 2, studies the key global Testosterone Replacement Therapy market competitors, their sales volume, market profits and price of Testosterone Replacement Therapy in 2015 and 2020;

Element 3, shows the competitive landscape view of global Testosterone Replacement Therapy market on the basis of dominant market players and their share in the market growth in 2015 and 2020;

Element 4, conducts the region-wise study of the global Testosterone Replacement Therapy market based on the sales ratio in each region, and market share from 2015 to 2020;

Element 5,6,7,8 and 9 demonstrates the key countries present in these regions which have revenue share in Testosterone Replacement Therapy market;

Element 10 and 11 describes the market based on Testosterone Replacement Therapy product category, wide range of applications, growth based on market trend, type and application 2015 to 2020;

Element 12 shows the global Testosterone Replacement Therapy market plans during the forecast period from 2020 to 2026 separated by regions, type, and product application.

Element 13, 14, 15 mentions the global Testosterone Replacement Therapy market sales channels, market vendors, dealers, market information and study conclusions, appendix and data sources.

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Testosterone Replacement Therapy Market- Revenue, Research Till 2026 Industry Influence Over Market - Reporting 99

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Carol Vorderman says she could ‘burst with happiness’ as ‘every little pleasure’ makes her ‘grin’ – Mirror Online

Posted: February 6, 2020 at 8:43 pm

Carol Vorderman is one happy lady!

The 58-year-old telly star has taken to Twitter to share that's she's happier than ever, and could "burst" in a rather cryptic post.

Sharing the update with her 424k loyal followers, the former Countdown star asked:

"Ever been so happy you could actually burst?"

Carol then went on to gush about the fact she's feeling over the moon all the time, and hasn't had a down day for as long as she can remember.

She continued: "I'm feeling like that 7 days a week now....every little pleasure makes me grin... Always been a very happy soul, but it's like it's become ephemeral".

Fans speculated her message might have something to so with her love life, but Carol has since tweeted back to insist that's not true.

She wrote: "It was about being happy, and nothing to do with sex. Life's never dull eh?"

One told told the TV star: "You shouldn't hide your happiness just because social media is such a negative space."

While another quipped: "You deserve this happiness and even more. Don't shy away from sharing your joy with the world!".

It comes after Carol, who is usually notoriously secret about her love life, dropped some huge hints in a newspaper interview last year.

Carol, who is believed to be single, admitted she enjoys a very active sex life in an interview with the Daily Mail.

She said: "I get up to a lot of mischief. I have a number of special friends - but Im not doing anything wrong.

"Everyones single. And yes, apart from one, theyre all younger than me."

The mum to two grown children said that she will never reveal the names of who she is dating.

Carol also said she feels she deserves more "me time" after years of caring for others, including her beloved mum who passed away two years ago.

The former Countdown star also opened up about the benefits of her menopause medication - supplemented with testosterone and oestregen gels - which she claims has enhanced her bum and bust.

Carol said she takes the hormone replacement therapy alongside plant-derived natural bio-identical hormones.

She told reporters that this was the reason behind her gravity-defying figure and her increased libido.

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Finasteride Market to trace exponential gain till 2025; boosted by the alopecia treatment industry – Technology Magazine

Posted: February 3, 2020 at 3:49 pm

U.S. Finasteride Market size may witness significant gains owing to its global dominance in alopecia treatment industry. North America generated over 2 billion revenue in alopecia market in 2015. Government approval to use finasteride in men hair loss treatment and other health problems accompanied by better results from other alternatives are influencing factors to foster regional growth.

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Positive outlook on pharmaceutical sector accompanied by increase in per capita income particularly in China and India should fuel Asia Pacific industry growth. As per industry estimates, around 20% males in China are suffering from hair loss due to hormonal changes which may stimulate China finasteride market demand.

Leading companies in the finasteride market

Major application in the finasteride market includes treatment of benign prostatic hyperplasia (BPH), male pattern baldness, hormone replacement therapy. The product is demonstrated effective in men; it has contrary effects on female and children thus it is recommended to be not in touch with the medicine. In BPH, the prostate gland becomes larger in older men which causes problems with passing urine as it is situated near bladder.

Finasteride Market addresses hair loss, brought about by change in consumer eating habits, sedentary lifestyle and rise in stress levels. Blocking the male hormone testosterone and conversion into androgen dihydrotestosterone (DHT), which is responsible for hair loss is intrinsic property responsible for global finasteride industry size growth.

Oral drugs market valuation was over USD 500 million in 2015and may exceed USD 990 million by 2024. The segment is gaining popularity due to its safe as well as minimum dosage intake with increased drug efficacy properties. Rising stress level among people due to change in lifestyle has led to early male-pattern baldness. Increase consumer disposable income coupled with presence of easy scalp treatment process may drive finasteride market demand.

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Testosterone Replacement Therapy Market 2020-2027 is booming in forthcoming year by Leading Players AbbVie – Briotainment

Posted: February 3, 2020 at 1:44 am

Global Testosterone Replacement Therapy Market Report assistances industry leaders to make confident capital investment decisions, develop strategic plans, optimize their business portfolio, innovate successfully and operate safely and sustainably. The report also offers a detailed summary of the industry including definitions, classifications, growth factors, applications and market chain structure, revenue development in terms of volume with respect to the Testosterone Replacement Therapy Market.

The report also embraces the absolute growth revenue value of the Testosterone Replacement Therapy Market across the globe over the forecast period 2020-2027. The Testosterone Replacement Therapy Market is anticipated to surpass more than US$ xxx million by 2027 at a CAGR of xx% in the given forecast period.

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Top Key Players Profiled in This Report: AbbVieEndo InternationalEli lillyPfizerActavis (Allergan)BayerNovartisTevaMylanUpsher-SmithFerring PharmaceuticalsKyowa KirinAcerus Pharmaceuticals

Testosterone Replacement Therapy Market report is the reliable source for obtaining the market study which will rapidly expand your business. A separate analysis of prevailing trends within the parent market and rules and mandates is enclosed underneath the ambit of the study. So, the report comes the attractiveness of every major section over the forecast amount.

The key countries in each region are taken into consideration as well, such as United States, China, Japan, India, Korea, ASEAN, Germany, France, UK, Italy, Spain, CIS, and Brazil etc.

Key Findings of the Global Testosterone Replacement Therapy Market:

What will the market size and the growth rate be in 2027?

What are the key factors driving the Global Testosterone Replacement Therapy Market?

What are the key market trends impacting the growth of the market?

What are the challenges to market growth?

Who are the key vendors in the Global Testosterone Replacement Therapy Market?

What are the market opportunities and threats faced by the vendors in this market?

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This research report represents a 360-degree overview of the competitive landscape of the Testosterone Replacement Therapy Market. Furthermore, it offers massive data relating to recent trends, technological advancements, tools, and methodologies. The research report analyzes the Testosterone Replacement Therapy Market in a detailed and concise manner for better insights into the businesses.

Major Factors:

1. Global Testosterone Replacement Therapy Market Overview

2. Economic Impact on Industry

3. Market Competition by Manufacturers

4. Production, Revenue (Value) by Region

5. Supply (Production), Consumption, Export, Import by Regions

6. Production, Revenue (Value), Price Trend by Type

7. Market Analysis by Application

8. Manufacturing Cost Analysis

9. Industrial Chain, Sourcing Strategy and Downstream Buyers

10. Marketing Strategy Analysis, Distributors/Traders

11. Market Effect Factors Analysis

12. Global Testosterone Replacement Therapy Market Forecast

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Testosterone Replacement Therapy Market 2020-2027 is booming in forthcoming year by Leading Players AbbVie - Briotainment

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Testosterone Replacement Therapy Market is Estimated to Grow at the Highest Growth Rate till 2020-2024 – Expedition 99

Posted: January 31, 2020 at 6:46 pm

The Testosterone Replacement Therapy Market Research Report aims to provide insights that strongly demonstrate the market structure, scope, history, potential, and development perspective. By crossing through the historical and present market status, the Testosterone Replacement Therapy market report provides authentic and reliable estimates for the forecast period.

It became essential to distinguish the saturation of consumption in the Testosterone Replacement Therapy market owing to building competitiveness. Hence, the report furnishes a deep-felt market segmentation analysis based on several segments such as types, applications, regions, and end-users. It serves to precise target the actual market size and product and service needs of customers. It also helps industry companies in promoting products that completely meet emerging customer needs.

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The report furnishes the analysis of market encounter, segmentation, leading market players, industry environment, and microeconomic factors that help clients, Testosterone Replacement Therapy companies, investors, officials, and researchers perceive ongoing market performance within a minute. The report also reveals in-depth details of shifting market dynamics, pricing structures, trends, restraints, limitations, demand-supply variations, growth-boosting factors, and market variations that have been considered the most important factors in the Testosterone Replacement Therapy market.

Comprehensive analysis of Testosterone Replacement Therapy market segment by manufactures:

The report also highlights its financial position by assessing gross margin, profitability, production cost, pricing structure, expenses, Testosterone Replacement Therapy sales volume, revenue, and growth rate. Their raw material sourcing strategies, organizational structure, corporate alliance, Testosterone Replacement Therapy production volume, manufacturing base, sales areas, distribution network, global presence, product specifications, effective technologies, major vendors, and import-export activities are also emphasized in this report.

The report includes profound importance for the individuals/companies operating and financing in the Testosterone Replacement Therapy market as AbbVie, Endo International, Eli lilly, Pfizer, Actavis (Allergan), Bayer, Novartis, Teva, Mylan, Upsher-Smith, Ferring Pharmaceuticals, it holds helpful insights that immediate to discover and interpret market demand, market size, share, and rivalry sitch. The report incorporates comprehensive market intelligence procured using both qualitative and quantitative research methods. It also contracts proficient systematic analytical studies including Porters Five Forces, SWOT analysis, and Probability analysis to review the market thoroughly.

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The report moreover presents a comprehensive representation of Testosterone Replacement Therapy manufacturers and companies who have been attempting to pose their dominance in the market in terms of sales, revenue, and growth. The report traverses their applications such as product research, development, innovation, and technology appropriation which supports them deliver more efficient product lineup in the industry. Profitable business plans, including acquiring, mergers, ventures, amalgamations, as well as product launches, and brand promotions are also elucidating in the report.

Comprehensive analysis of Testosterone Replacement Therapy market segment Type, Application:

Furthermore, it explores various requisite segments of the global Testosterone Replacement Therapy market such as types, applications, regions, and technologies. The report grants a comprehensive analysis of each market acknowledging market acceptance, attractiveness, demand, production, and predicted sales revenue by Type(Gels, Injections, Patches, Other) and by Application(Hospitals, Clinics, Others). The segmentation analysis helps consumers to select suitable segments for their Testosterone Replacement Therapy business and specifically target the wants and needs of their existing and potential customer base.

Comprehensive analysis of Testosterone Replacement Therapy market segment by Regional Anlaysis:

The report focuses on regional coverage across the globe principally with respect to x-x Units, revenue (Million USD), market share and growth rate variable with in each region depending upon its capacity. Regions that have been covered for this market included Asia-Pacific, Europe, North America, Middle East & Africa, South America

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Testosterone Replacement Therapy Market is Estimated to Grow at the Highest Growth Rate till 2020-2024 - Expedition 99

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Testosterone Replacement Therapy or Hormone Replacement Therapy? – Reno Hotline

Posted: January 30, 2020 at 3:50 pm

If you have a confirmed testosterone deficiency, its important to identify if there are any reversible causes that can be addressed before committing to, what should be considered a lifelong therapy. Testosterone Replacement Therapy (TRT) is an involved process. In my professional opinion, the most effective method of replacement is daily Testosterone Cypionate and Human Chorionic Gonadotropin (HCG) injections. Your dose is carefully titrated to normalise your male androgen levels.

TRT is an involved process, its a financial commitment and its a time-consuming process. Two daily subcutaneous injections, admittedly with a tiny 29-gauge insulin needle, preparation of your multi-dose vial, every 3 months for Testosterone Cypionate and monthly for HCG, regular blood tests, additional blood tests after a protocol change. We have patients from all over the UK, Europe and further afield, they all have an initial face to face consultation and yearly thereafter, the rest can be managed remotely. Some of my patients travel thousands of miles, Denmark, Norway, Spain, Portugal, Dubai, the Philippines to ensure they receive Gold Standard care. Londoners often complain a trip to Poole is too far, little do they know.

TRT has traditionally been thought of as simply replacing the testosterone. It makes sense, replace the testosterone that is deficient. The issue lies with the subsequent negative effect on other important parameters administration of exogenous testosterone has on the body. Injecting testosterone shuts down the Hypo-pituitary Gonadal (HPG) axis, you know longer produce Lutenising Hormone (LH) and Follicle Stimulating Hormone (FSH) from the pituitary gland in the brain. LH stimulates the Leydig cells of the testes to produce testosterone, the FSH stimulates the Sertoli cells to produce sperm through a process called spermatogenesis.

HCG mimics LH, it is used in the treatment of male infertility. Intra-testicular testosterone is partly converted to oestradiol by the aromatase enzyme, this helps facilitate spermatogenesis. The Mens Health Clinic now has 20 pregnancies with the concurrent use of HCG alongside testosterone. Its important to appreciate that there are LH receptors all over the body, most noticeably the brain. HCG is clearly important to help maintain fertility and testicular size, but its effects are more wide ranging. Men report an improved sense of well-being and libido using HCG alongside testosterone.

I am uncomfortable with allowing an organ, in this case your testicles, to atrophy with testosterone monotherapy. It seems illogical to me that this should be accepted. I believe that irrespective of whether you want to conceive or not, you should replace this hormone. TRT should be considered hormone replacement therapy (HRT), we should be maintaining function with HCG and supplementing with testosterone to ensure your male androgen levels are normalised.

I am rather shocked and appalled that the medical community has such a simplistic approach to TRT, as one NHS Endocrinologist recently said to me either the patient wants to retain fertility in which case you offer HCG or they do not want to retain fertility in which case you treat with testosterone. This regressive and outdated attitude and approach to TRT is one of the reasons men are willing to travel from all over the world to The Mens Health Clinic, Gold Standard care.

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Testosterone Replacement Therapy or Hormone Replacement Therapy? - Reno Hotline

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Healthy Men: Benefits of male hormone replacement therapy – Duluth News Tribune

Posted: January 29, 2020 at 2:41 am

Q: A recent news release suggested that men with low testosterone levels may have improvement in sexual function and quality of life. How can I determine whether I can benefit and what questions should I ask my doctor?

A: Before we get into the details of the newly reported benefits of testosterone therapy including the scope of those benefits and the men most likely to see them lets talk about what, exactly, testosterone is, what it does, and what constitutes low levels (also sometimes referred to as low T, andropause, or even male menopause).

To start with, testosterone is the most important male hormone (although women have measurable levels as well). In a nutshell, its what makes men men at least physically. Its manufactured in the testicles and plays a significant role in puberty (including penis and testicle growth and voice deepening), muscle and bone growth and development, strength, sex drive, and fertility.

Testosterone levels are usually measured with a blood test and are reported in terms of nanograms per deciliter (abbreviated as ng/dL). The normal range for men 20-70 is 300-1000 ng/dL. However, starting at about age 30, mens levels gradually decrease by an average of 1-2% per year. According to the journal Annals of Internal Medicine, the symptoms of low testosterone include little or no interest in sex, erectile dysfunction, less energy/feeling weak, mood changes and feeling depressed, loss of bone mineral density, and loss of body and facial hair. However, there is significant debate as to whether these symptoms are truly associated with low testosterone or if they are a result of other factors, such as chronic illness or certain medications.

Studies have found that 20%-40% of males ages 30-70 have low testosterone levels (although its important to note that not all of them will have any negative symptoms).

Okay, now lets talk about the news stories you may have heard about. The study in question evaluated 38 other high-quality studies and focused on men with age-related low testosterone and the effects of testosterone replacement therapy (TRT). The findings were fairly limited: Overall, men who received TRT experienced small improvements in sexual function and quality of life. The researchers did not find that TRT offered any benefits for other age-related issues, such as lack of energy, mood, strength, memory, or cognitive ability. And they were unable to shed any new light on any of the previously reported links between testosterone replacement therapy and heart health, prostate cancer, or mortality.

So, what should you do if you think you might have age-related low testosterone? The Washington DC-based non-profit, Mens Health Network (menshealthnetwork.org), recommends that you discuss your symptoms with your doctor and ask for a blood test. If your levels come back low, you should ask your doctor the following questions recommended by the American College of Physicians (ACP): Will taking TRT help with the symptoms that I came to discuss with you? What method of TRT is best for me? What are the risks and side effects of treatment? And How long will it take for TRT to work, and what if it does not work?

Mens Health Network supports the ACPs guidelines, which recommend that doctors consider offering TRT via intramuscular injection rather than a patch, gel, or pellet. The ACP believes that injections are cheaper, yet just as effective as other methods and involve similar side effects. However, they recognize that injections (which will need to happen every 1-4 weeks) may not be for everyone.

Armin Brott is the author of Blueprint for Mens Health, Your Head: An Owners Manual, and many other works on mens health. Visit him at HealthyMenToday.com.

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Healthy Men: Benefits of male hormone replacement therapy - Duluth News Tribune

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