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Hormone Replacement Therapy Market Study for 2020 to 2026 Providing Information on Key Players, Growth Drivers and Industry Challenges|Pfizer, AbbVie,…

Posted: May 5, 2020 at 8:43 pm

Complete study of the global Hormone Replacement Therapy market is carried out by the analysts in this report, taking into consideration key factors like drivers, challenges, recent trends, opportunities, advancements, and competitive landscape. This report offers a clear understanding of the present as well as future scenario of the global Hormone Replacement Therapy industry. Research techniques like PESTLE and Porters Five Forces analysis have been deployed by the researchers. They have also provided accurate data on Hormone Replacement Therapy production, capacity, price, cost, margin, and revenue to help the players gain a clear understanding into the overall existing and future market situation.

Key companies operating in the global Hormone Replacement Therapy market include , Eli Lilly, Pfizer, AbbVie, Novo Nordisk, Merck KGaA, Mylan, Bayer, Teva, Novartis, Abbott, Roche, Endo International, Ipsen, ANI Pharmaceuticals, TherapeuticsMD Hormone Replacement Therapy

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Segmental Analysis

The report has classified the global Hormone Replacement Therapy industry into segments including product type and application. Every segment is evaluated based on growth rate and share. Besides, the analysts have studied the potential regions that may prove rewarding for the Hormone Replacement Therapy manufcaturers in the coming years. The regional analysis includes reliable predictions on value and volume, thereby helping market players to gain deep insights into the overall Hormone Replacement Therapy industry.

Global Hormone Replacement Therapy Market Segment By Type:

, Estrogen Hormone, Growth Hormone, Thyroid Hormone, Testosterone Hormone, The proportion of estrogen hormone in 2018 is about 50%, and the proportion is in increasing trend from 2014 to 2018. Hormone Replacement Therapy

Global Hormone Replacement Therapy Market Segment By Application:

Menopause, Hypothyroidism, Growth Hormone Deficiency, Male Hypogonadism, Other Diseases

Competitive Landscape

It is important for every market participant to be familiar with the competitive scenario in the global Hormone Replacement Therapy industry. In order to fulfil the requirements, the industry analysts have evaluated the strategic activities of the competitors to help the key players strengthen their foothold in the market and increase their competitiveness.

Key companies operating in the global Hormone Replacement Therapy market include , Eli Lilly, Pfizer, AbbVie, Novo Nordisk, Merck KGaA, Mylan, Bayer, Teva, Novartis, Abbott, Roche, Endo International, Ipsen, ANI Pharmaceuticals, TherapeuticsMD Hormone Replacement Therapy

Key questions answered in the report:

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TOC

1 Study Coverage1.1 Hormone Replacement Therapy Product Introduction1.2 Market Segments1.3 Key Hormone Replacement Therapy Manufacturers Covered: Ranking by Revenue1.4 Market by Type1.4.1 Global Hormone Replacement Therapy Market Size Growth Rate by Type1.4.2 Estrogen Hormone1.4.3 Growth Hormone1.4.4 Thyroid Hormone1.4.5 Testosterone Hormone1.5 Market by Application1.5.1 Global Hormone Replacement Therapy Market Size Growth Rate by Application1.5.2 Menopause1.5.3 Hypothyroidism1.5.4 Growth Hormone Deficiency1.5.5 Male Hypogonadism1.5.6 Other Diseases1.6 Coronavirus Disease 2019 (Covid-19): Hormone Replacement Therapy Industry Impact1.6.1 How the Covid-19 is Affecting the Hormone Replacement Therapy Industry1.6.1.1 Hormone Replacement Therapy Business Impact Assessment Covid-191.6.1.2 Supply Chain Challenges1.6.1.3 COVID-19s Impact On Crude Oil and Refined Products1.6.2 Market Trends and Hormone Replacement Therapy Potential Opportunities in the COVID-19 Landscape1.6.3 Measures / Proposal against Covid-191.6.3.1 Government Measures to Combat Covid-19 Impact1.6.3.2 Proposal for Hormone Replacement Therapy Players to Combat Covid-19 Impact1.7 Study Objectives1.8 Years Considered 2 Executive Summary2.1 Global Hormone Replacement Therapy Market Size Estimates and Forecasts2.1.1 Global Hormone Replacement Therapy Revenue 2015-20262.1.2 Global Hormone Replacement Therapy Sales 2015-20262.2 Hormone Replacement Therapy Market Size by Region: 2020 Versus 20262.2.1 Global Hormone Replacement Therapy Retrospective Market Scenario in Sales by Region: 2015-20202.2.2 Global Hormone Replacement Therapy Retrospective Market Scenario in Revenue by Region: 2015-2020 3 Global Hormone Replacement Therapy Competitor Landscape by Players3.1 Hormone Replacement Therapy Sales by Manufacturers3.1.1 Hormone Replacement Therapy Sales by Manufacturers (2015-2020)3.1.2 Hormone Replacement Therapy Sales Market Share by Manufacturers (2015-2020)3.2 Hormone Replacement Therapy Revenue by Manufacturers3.2.1 Hormone Replacement Therapy Revenue by Manufacturers (2015-2020)3.2.2 Hormone Replacement Therapy Revenue Share by Manufacturers (2015-2020)3.2.3 Global Hormone Replacement Therapy Market Concentration Ratio (CR5 and HHI) (2015-2020)3.2.4 Global Top 10 and Top 5 Companies by Hormone Replacement Therapy Revenue in 20193.2.5 Global Hormone Replacement Therapy Market Share by Company Type (Tier 1, Tier 2 and Tier 3)3.3 Hormone Replacement Therapy Price by Manufacturers3.4 Hormone Replacement Therapy Manufacturing Base Distribution, Product Types3.4.1 Hormone Replacement Therapy Manufacturers Manufacturing Base Distribution, Headquarters3.4.2 Manufacturers Hormone Replacement Therapy Product Type3.4.3 Date of International Manufacturers Enter into Hormone Replacement Therapy Market3.5 Manufacturers Mergers & Acquisitions, Expansion Plans 4 Breakdown Data by Type (2015-2026)4.1 Global Hormone Replacement Therapy Market Size by Type (2015-2020)4.1.1 Global Hormone Replacement Therapy Sales by Type (2015-2020)4.1.2 Global Hormone Replacement Therapy Revenue by Type (2015-2020)4.1.3 Hormone Replacement Therapy Average Selling Price (ASP) by Type (2015-2026)4.2 Global Hormone Replacement Therapy Market Size Forecast by Type (2021-2026)4.2.1 Global Hormone Replacement Therapy Sales Forecast by Type (2021-2026)4.2.2 Global Hormone Replacement Therapy Revenue Forecast by Type (2021-2026)4.2.3 Hormone Replacement Therapy Average Selling Price (ASP) Forecast by Type (2021-2026)4.3 Global Hormone Replacement Therapy Market Share by Price Tier (2015-2020): Low-End, Mid-Range and High-End 5 Breakdown Data by Application (2015-2026)5.1 Global Hormone Replacement Therapy Market Size by Application (2015-2020)5.1.1 Global Hormone Replacement Therapy Sales by Application (2015-2020)5.1.2 Global Hormone Replacement Therapy Revenue by Application (2015-2020)5.1.3 Hormone Replacement Therapy Price by Application (2015-2020)5.2 Hormone Replacement Therapy Market Size Forecast by Application (2021-2026)5.2.1 Global Hormone Replacement Therapy Sales Forecast by Application (2021-2026)5.2.2 Global Hormone Replacement Therapy Revenue Forecast by Application (2021-2026)5.2.3 Global Hormone Replacement Therapy Price Forecast by Application (2021-2026) 6 North America6.1 North America Hormone Replacement Therapy by Country6.1.1 North America Hormone Replacement Therapy Sales by Country6.1.2 North America Hormone Replacement Therapy Revenue by Country6.1.3 U.S.6.1.4 Canada6.2 North America Hormone Replacement Therapy Market Facts & Figures by Type6.3 North America Hormone Replacement Therapy Market Facts & Figures by Application 7 Europe7.1 Europe Hormone Replacement Therapy by Country7.1.1 Europe Hormone Replacement Therapy Sales by Country7.1.2 Europe Hormone Replacement Therapy Revenue by Country7.1.3 Germany7.1.4 France7.1.5 U.K.7.1.6 Italy7.1.7 Russia7.2 Europe Hormone Replacement Therapy Market Facts & Figures by Type7.3 Europe Hormone Replacement Therapy Market Facts & Figures by Application 8 Asia Pacific8.1 Asia Pacific Hormone Replacement Therapy by Region8.1.1 Asia Pacific Hormone Replacement Therapy Sales by Region8.1.2 Asia Pacific Hormone Replacement Therapy Revenue by Region8.1.3 China8.1.4 Japan8.1.5 South Korea8.1.6 India8.1.7 Australia8.1.8 Taiwan8.1.9 Indonesia8.1.10 Thailand8.1.11 Malaysia8.1.12 Philippines8.1.13 Vietnam8.2 Asia Pacific Hormone Replacement Therapy Market Facts & Figures by Type8.3 Asia Pacific Hormone Replacement Therapy Market Facts & Figures by Application 9 Latin America9.1 Latin America Hormone Replacement Therapy by Country9.1.1 Latin America Hormone Replacement Therapy Sales by Country9.1.2 Latin America Hormone Replacement Therapy Revenue by Country9.1.3 Mexico9.1.4 Brazil9.1.5 Argentina9.2 Central & South America Hormone Replacement Therapy Market Facts & Figures by Type9.3 Central & South America Hormone Replacement Therapy Market Facts & Figures by Application 10 Middle East and Africa10.1 Middle East and Africa Hormone Replacement Therapy by Country10.1.1 Middle East and Africa Hormone Replacement Therapy Sales by Country10.1.2 Middle East and Africa Hormone Replacement Therapy Revenue by Country10.1.3 Turkey10.1.4 Saudi Arabia10.1.5 UAE10.2 Middle East and Africa Hormone Replacement Therapy Market Facts & Figures by Type10.3 Middle East and Africa Hormone Replacement Therapy Market Facts & Figures by Application 11 Company Profiles11.1 Eli Lilly11.1.1 Eli Lilly Corporation Information11.1.2 Eli Lilly Description, Business Overview and Total Revenue11.1.3 Eli Lilly Sales, Revenue and Gross Margin (2015-2020)11.1.4 Eli Lilly Hormone Replacement Therapy Products Offered11.1.5 Eli Lilly Recent Development11.2 Pfizer11.2.1 Pfizer Corporation Information11.2.2 Pfizer Description, Business Overview and Total Revenue11.2.3 Pfizer Sales, Revenue and Gross Margin (2015-2020)11.2.4 Pfizer Hormone Replacement Therapy Products Offered11.2.5 Pfizer Recent Development11.3 AbbVie11.3.1 AbbVie Corporation Information11.3.2 AbbVie Description, Business Overview and Total Revenue11.3.3 AbbVie Sales, Revenue and Gross Margin (2015-2020)11.3.4 AbbVie Hormone Replacement Therapy Products Offered11.3.5 AbbVie Recent Development11.4 Novo Nordisk11.4.1 Novo Nordisk Corporation Information11.4.2 Novo Nordisk Description, Business Overview and Total Revenue11.4.3 Novo Nordisk Sales, Revenue and Gross Margin (2015-2020)11.4.4 Novo Nordisk Hormone Replacement Therapy Products Offered11.4.5 Novo Nordisk Recent Development11.5 Merck KGaA11.5.1 Merck KGaA Corporation Information11.5.2 Merck KGaA Description, Business Overview and Total Revenue11.5.3 Merck KGaA Sales, Revenue and Gross Margin (2015-2020)11.5.4 Merck KGaA Hormone Replacement Therapy Products Offered11.5.5 Merck KGaA Recent Development11.6 Mylan11.6.1 Mylan Corporation Information11.6.2 Mylan Description, Business Overview and Total Revenue11.6.3 Mylan Sales, Revenue and Gross Margin (2015-2020)11.6.4 Mylan Hormone Replacement Therapy Products Offered11.6.5 Mylan Recent Development11.7 Bayer11.7.1 Bayer Corporation Information11.7.2 Bayer Description, Business Overview and Total Revenue11.7.3 Bayer Sales, Revenue and Gross Margin (2015-2020)11.7.4 Bayer Hormone Replacement Therapy Products Offered11.7.5 Bayer Recent Development11.8 Teva11.8.1 Teva Corporation Information11.8.2 Teva Description, Business Overview and Total Revenue11.8.3 Teva Sales, Revenue and Gross Margin (2015-2020)11.8.4 Teva Hormone Replacement Therapy Products Offered11.8.5 Teva Recent Development11.9 Novartis11.9.1 Novartis Corporation Information11.9.2 Novartis Description, Business Overview and Total Revenue11.9.3 Novartis Sales, Revenue and Gross Margin (2015-2020)11.9.4 Novartis Hormone Replacement Therapy Products Offered11.9.5 Novartis Recent Development11.10 Abbott11.10.1 Abbott Corporation Information11.10.2 Abbott Description, Business Overview and Total Revenue11.10.3 Abbott Sales, Revenue and Gross Margin (2015-2020)11.10.4 Abbott Hormone Replacement Therapy Products Offered11.10.5 Abbott Recent Development11.1 Eli Lilly11.1.1 Eli Lilly Corporation Information11.1.2 Eli Lilly Description, Business Overview and Total Revenue11.1.3 Eli Lilly Sales, Revenue and Gross Margin (2015-2020)11.1.4 Eli Lilly Hormone Replacement Therapy Products Offered11.1.5 Eli Lilly Recent Development11.12 Endo International11.12.1 Endo International Corporation Information11.12.2 Endo International Description, Business Overview and Total Revenue11.12.3 Endo International Sales, Revenue and Gross Margin (2015-2020)11.12.4 Endo International Products Offered11.12.5 Endo International Recent Development11.13 Ipsen11.13.1 Ipsen Corporation Information11.13.2 Ipsen Description, Business Overview and Total Revenue11.13.3 Ipsen Sales, Revenue and Gross Margin (2015-2020)11.13.4 Ipsen Products Offered11.13.5 Ipsen Recent Development11.14 ANI Pharmaceuticals11.14.1 ANI Pharmaceuticals Corporation Information11.14.2 ANI Pharmaceuticals Description, Business Overview and Total Revenue11.14.3 ANI Pharmaceuticals Sales, Revenue and Gross Margin (2015-2020)11.14.4 ANI Pharmaceuticals Products Offered11.14.5 ANI Pharmaceuticals Recent Development11.15 TherapeuticsMD11.15.1 TherapeuticsMD Corporation Information11.15.2 TherapeuticsMD Description, Business Overview and Total Revenue11.15.3 TherapeuticsMD Sales, Revenue and Gross Margin (2015-2020)11.15.4 TherapeuticsMD Products Offered11.15.5 TherapeuticsMD Recent Development 12 Future Forecast by Regions (Countries) (2021-2026)12.1 Hormone Replacement Therapy Market Estimates and Projections by Region12.1.1 Global Hormone Replacement Therapy Sales Forecast by Regions 2021-202612.1.2 Global Hormone Replacement Therapy Revenue Forecast by Regions 2021-202612.2 North America Hormone Replacement Therapy Market Size Forecast (2021-2026)12.2.1 North America: Hormone Replacement Therapy Sales Forecast (2021-2026)12.2.2 North America: Hormone Replacement Therapy Revenue Forecast (2021-2026)12.2.3 North America: Hormone Replacement Therapy Market Size Forecast by Country (2021-2026)12.3 Europe Hormone Replacement Therapy Market Size Forecast (2021-2026)12.3.1 Europe: Hormone Replacement Therapy Sales Forecast (2021-2026)12.3.2 Europe: Hormone Replacement Therapy Revenue Forecast (2021-2026)12.3.3 Europe: Hormone Replacement Therapy Market Size Forecast by Country (2021-2026)12.4 Asia Pacific Hormone Replacement Therapy Market Size Forecast (2021-2026)12.4.1 Asia Pacific: Hormone Replacement Therapy Sales Forecast (2021-2026)12.4.2 Asia Pacific: Hormone Replacement Therapy Revenue Forecast (2021-2026)12.4.3 Asia Pacific: Hormone Replacement Therapy Market Size Forecast by Region (2021-2026)12.5 Latin America Hormone Replacement Therapy Market Size Forecast (2021-2026)12.5.1 Latin America: Hormone Replacement Therapy Sales Forecast (2021-2026)12.5.2 Latin America: Hormone Replacement Therapy Revenue Forecast (2021-2026)12.5.3 Latin America: Hormone Replacement Therapy Market Size Forecast by Country (2021-2026)12.6 Middle East and Africa Hormone Replacement Therapy Market Size Forecast (2021-2026)12.6.1 Middle East and Africa: Hormone Replacement Therapy Sales Forecast (2021-2026)12.6.2 Middle East and Africa: Hormone Replacement Therapy Revenue Forecast (2021-2026)12.6.3 Middle East and Africa: Hormone Replacement Therapy Market Size Forecast by Country (2021-2026) 13 Market Opportunities, Challenges, Risks and Influences Factors Analysis13.1 Market Opportunities and Drivers13.2 Market Challenges13.3 Market Risks/Restraints13.4 Porters Five Forces Analysis13.5 Primary Interviews with Key Hormone Replacement Therapy Players (Opinion Leaders) 14 Value Chain and Sales Channels Analysis14.1 Value Chain Analysis14.2 Hormone Replacement Therapy Customers14.3 Sales Channels Analysis14.3.1 Sales Channels14.3.2 Distributors 15 Research Findings and Conclusion 16 Appendix16.1 Research Methodology16.1.1 Methodology/Research Approach16.1.2 Data Source16.2 Author Details

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Hormone Replacement Therapy Market Study for 2020 to 2026 Providing Information on Key Players, Growth Drivers and Industry Challenges|Pfizer, AbbVie,...

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The secret life of an anonymous speechwriter to the stars – The Guardian

Posted: May 4, 2020 at 10:45 am

I write speeches for people who can barely read their scripts because public speaking makes them nervous (statistically, public speaking is the number one fear, worse even than death). I write for people who are so compelling and beautiful that they could recite the alphabet and get a standing ovation. I write arguments that are recited in the House and Senate, in the seats of power. My words are on television and in stadiums that hold thousands of eager listeners. Im not there at all. The speeches, toasts and rallying cries I write go further than I ever will: I may not be seen, but I am heard. The words that do not matter when I speak for myself are amplified when I put them in the mouths of others. Because as anyone knows, its not just the words that matter. Its who says them, and when, and how.

Before I started writing for reality TV stars, musicians, political leaders and lecturers, I assumed that everyone wrote their own lines. Why wouldnt I think that? A well-written speech sounds like the person whos giving it. Or at least, it sounds like the person the speaker wants you to believe they are. Now I know that I was naive to assume that any public figure, even one who is a good writer, writes their own speeches and biographies and other ephemera. Ive learned that you are probably hearing something written in the style of by a very talented mimic.

Im an excellent mimic. This makes me a good speechwriter, but when I came out as nonbinary trans, it also became a survival skill. My welfare often depends on whether the non-transgender people around me see me as fully human and that means knowing exactly what to say, when, and in what tone. I needed to sound confident but not overbearing; friendly but not obsequious. My masculine presentation had to be balanced by kindness, consideration of others, and a willingness to cede the floor. I couldnt afford to blunder through any conversation, and I approached every interaction with more awareness and intention than ever before. Honestly, I spent a lot of time thinking about what Fred Rogers would say.

The only place where I didnt need to moderate my tone, where I could speak freely, was in my addiction recovery community. Through the first, dramatic stages of my transition, when my voice broke and when I was so afraid that my anger and panic was unwelcome in the world, the friends I knew there listened to me and encouraged me to keep sharing. They understood that, for people like us, honesty is lifesaving. People who swallowed their feelings relapsed, disappeared and died. I lost many friends to overdoses and substance-related accidents and suicides, silent deaths that went unacknowledged outside of our community. I kept showing up, and I kept talking. Tears, bile, all of me was welcome.

Outside of meetings, I couldnt express myself with the same openness. Although the words I spoke didnt change, my voice and the way I sounded altered the way that others heard me. Short statements, in a deep, gruff voice, can be heard as controlling, dismissive or rude, a sign of un-self-aware male privilege. The anger that commanded respect and interest when I presented as female became a liability as my voice lowered, acquiring the tones of patriarchy. Each word carried more weight, bigger consequences than before. Id had practice writing speeches for other people. Now, I had to learn new lines that were right for my voice and the body that carried it. Once my voice hit a certain frequency, I became my own ghostwriting client: how did I want to be perceived? What character was I playing now?

I started ghostwriting at the end of Barack Obamas first term as president. His writer, Jon Favreau, wrote sonorous lines for Obama. Those wide, soft vowels became musical. Like Winston Churchills, Obamas speeches were written in psalm-form, blocks that mimic the way people speak when they are going off script. The euphony in Obamas campaign speeches, alternately fiery and soothing, changed to the melody of authority once he was in office. I listened to Obama lean on the linguistic patterns of pastors, visionaries and teachers. His speeches used simple, two-syllable words, to avoid making him seem too much like an arugula-eating liberal. They had a signature three-verse structure, with a bridge in the middle. Once Id heard this music, I couldnt un-hear it.

The first time I wrote a speech for money, I was working as a research assistant for the manager of a hedge fund in Oregon. Dave* was also a member of a secret society that met annually for a black-and-white gala dedicated to the brilliance of Winston Churchill. At this gala, he told me, everyone wore a real tuxedo, penguin-style, with tails and a top hat. They slugged gallons of Churchills favorite drink Beefeater martinis and chomped cigars. The gala was a tense time, Dave explained, because of the elaborate system of speeches. Depending on his place in the hierarchy, any one of the guests would be expected to rise and disgorge a brief, bon-motstudded toast.

At that time, my voice was much higher, smoother and sweeter. I had not started hormone replacement therapy (HRT), and I still sounded like a woman. People dont listen to womens voices; they hear women speaking, but not the words they say. Research shows that voices with higher pitches, vocal fry, feminine vocal characteristics like a lisp, and gendered vocal tics such as the repeated use of like are ignored. Over five decades, the fundamental frequency of a test group of womens voices dropped by 23Hz, which correlates with womens entry into a previously male-dominated workplace. I did not have a high voice, but it was undeniably female. I was used to being read as a woman, discounted and ignored. The idea of Dave saying my words to a group of powerful, wealthy strangers shook something loose in me.

There were two caveats: the toast had to include a quote from Churchill that had never been used before, in the hundred-year history of the club; and it had to be short. I labored over this speech, getting stuck on all of the things I would say if I were the one in the spotlight. I could only hear myself and my own opinions. A speech like that would never make it into Daves shirt pocket, much less be read at this gala. I needed to alter my voice. I spent eight hours a day listening to Dave on the phone, as he bragged about the pitchers of sangria the waitress used to bring them from the VQ Cafe, back when Dave was a big deal, when he was young, before this dotcom bullshit. I knew exactly what he sounded like and how he wanted to be heard.

I imagined him, drunk and puffy in his Churchill costume, one hand on the tablecloth next to a plus-size martini and a half-eaten slab of roast beef smeared across a china plate, listing to port as he read the remarks Id written for him. I heard his voice, the money-basted sound of arrogant privilege. I looked at the toast again, picked up my pen, and started over. I was a good listener. I nailed it.

The speech I wrote for Dave was the first of many, and it worked because I stopped trying to write a speech and started imitating the best version of Dave. I wrote a script for the character he wanted to play that night, and it worked. For the duration of my job with him, I wrote his emails, fundraising letters and other speeches. I mocked him to my friends, pitch-perfect lines that could have come right out of his mouth. I said the things he hadnt thought of yet.

For the next six years, I wrote more speeches, lectures and manuscripts, mostly for people who didnt know who I was, aside from the writer. I didnt identify my gender when I did this work. I was just a voice on the phone, transcribing our conversations into ideas and paragraphs that would move an audience to the desired result. Want a million dollars in donations? I can write a speech that will achieve that. Want to pass lifesaving legislation? I can write one for that too. Want to change the way your audience feels about love, survival, health, politics, literature, community or hope? Thats my bread and butter. Sometimes, I wrote for people whose beliefs were diametrically opposed to my own. They were not difficult to mimic. In fact, those pieces were the easiest, because I could never confuse their voices for my own.

Then I started my physical transition. Within a couple of months on testosterone, I developed the usual hoarseness as the hormones affected my vocal fold structure, tissue integrity and thickness. My voice started to drop, a second adolescence. Yet my expressions did not change. When I spoke, my cadence and word choices were still female. I wandered around my subjects and avoided direct answers or simple statements. I preferred to agree without saying yes, refuse without saying no. I wrote in my clients voices, transcribing their desires. I went to meetings and barked about the unmanageable problems in my life: cravings, friends who caught a bad batch and didnt wake up, my disintegrating relationship with my immediate family, my fear of the painkillers that came with top surgery. It was a hard time. I was grateful for any ear, any place where I could go off script.

As I became audibly and physically queer, those spaces disappeared entirely. Id been socialized as female and already knew not to be abrasive in mixed company or share my opinions; before my transition, Id had the distinct experiences of being ignored and talked over by men. However, after a while, cis women stopped hearing me too. Or they heard me but didnt listen. My voice was husky from the early months of HRT. It was weak and airy, as though I had a throat cold; it vaporized in group conversations. I coughed out an idea and watched it disappear. More than once, I shared an opinion in a group and was ignored, but I noticed that when someone else parroted what Id said, they were acknowledged. I was afraid to speak up and challenge others conditional acceptance of me. I had so few places to go where I felt safe, giving up some airtime felt like a fair trade.

I stopped making declarative statements, stopped asserting myself. I kept quiet and listened. I reasoned that my actions spoke louder than my words, and that I didnt need my opinions or feelings acknowledged in order for them to be valid. There was no point in debating with people who didnt hear me when I spoke. I could let most ideas float by, unchallenged and unexplored. They were just noise. They didnt matter.

Then, I was hired to write a piece of testimony for a client, woven together with his personal experience with recovery from addiction. I wrote the first draft straight, drawing from his notes, but I barely had to glance at them to know what I needed to say. I was listening to my own story. Like me, my client had lost friends to preventable overdoses. He, too, struggled to make his voice heard outside of the recovery community. Unlike me, he had found a way and was using his story to create real change. He had access to lawmakers: he was meeting with Congress members, pushing policy to make sure naloxone was available in every sober living home in his state. His story was powerful and it burned in my ears as I wrote it down. I believed what I was writing; I felt the message. Although I wrote in my clients distinctive voice, I knew I was also speaking for myself.

I read the speech out loud in my studio to a hanging photo of my father. I recited it in the park to a smattering of pigeons. I heard the speechs music and the deep, implacable rage underneath it. Although Id written it for my client, I heard my own voice in it. What would I say if I wasnt afraid? I wished I could stand on a stage in front of hundreds of sign-clutching protesters and demand justice, as this client would, jabbing his finger toward the sky. Our time is now. What would I say if people actually listened? I went over the speech again, fine-tuning its message. I imagined my client, one of the bravest people I knew. I wanted to give him words that would speak for him, for me, for everyone who was listening. Every syllable had to move his audience. Lives hung in the balance: if the speech failed, that was one step back. The legislation tied to it might not pass. More people would die.

When I was done, I felt like Id handed over a piece of my heart. Id never cared so much before or put all of myself on the page that way. Id given the best of myself, the self I wished others perceived.

My client delivered the speech. His legislation passed. The news wire picked up the story, amplifying his words. The ripples spread. Later that week, I watched a video of my client on the day he read his story and had the jarring experience of hearing my voice come out of someone elses mouth. From his inflections to his gestures, we could have been mirror images. The crowd roared in all the right places. They resonated with the same passion Id felt when my client first hired me to write for him: his courage, transmittable, went from him to me to the massive audience that hung on his every word.

Although Id set out to be the channel for my clients voice, I had received so much more. I felt his confidence as he spoke. Writing for him awakened my own voice. The next time I heard an acquaintance sneer about dirty addicts who were a waste of resources, I cleared my throat. The person turned to me, eyes narrowed.

Fewer than 10% of people with substance use disorder ever get help of any kind because of stigmatizing language like dirty or clean, I said. The speech Id written trickled out of my mouth. Even people with substantial periods of recovery need support for their mental health. Addiction isnt a moral failing, and its not fair to frame it that way.

To my surprise, they nodded, leaned closer. They heard me. They listened.

* Daves name has been changed.

This story originally appeared on the digital storytelling platform Narratively. Looking for more great work? Here are some suggestions:

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The secret life of an anonymous speechwriter to the stars - The Guardian

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WWE news: Mick Foley wants Nancy Benoit inducted into Hall of Fame – GIVEMESPORT

Posted: May 2, 2020 at 5:46 pm

WWE icon Mick Foley has called for Chris Benoits tragically murdered wife Nancy to be inducted into the WWE Hall of Fame.

In 2007 over a three-day period, between June 22 and June 24, Benoit brutally murdered his wife Nancy and suffocated their seven-year-old son before hanging himself.

In an attempt to remember Nancys life in a different way, Foley has suggested that inducting her into the WWE Hall of Fame would be fitting.

The WWE originally paid tribute to Benoit, but after the murders were uncovered, he was completely erased from the companys history.

Foley took to social media to vent his thoughts, he said: For the past 13 years, Nancy Benoits life has been largely defined in the public eye by how she died. I think it is about time we changed that way of thinking.

Wouldnt it be nice if we could pause for a moment to remember instead, how she lived, how she worked, and to reflect on what her legacy in pro wrestling should be?

After the ring legend reached out to Sandra Toffoloni, Nancys sister, the two instantly started reflecting on the past.

Foley worked closely with Nancy in ECW and even closer with her when Benoit moved to WWE in 2000.

In a separate social media post, Foley addressed his proposal further, as he said: "Its an important discussion. But equally important to me, is that several fans, started talking about the career of Nancy Benoit, and how she should be remembered.

"For the first time I can recall, talk surfaced of Nancy possibly being inducted into the WWE Hall of Fame - a topic I had never really considered it before.

"But seeing the 'Dark Side of the Ring', re-establishing contact with Sandra, and looking back on Nancys career these past couple of weeks has been an eye-opener for me."

The brutal killings of Nancy and seven-year-old Daniel, as well as the suicide of Chris Benoit, were documented on a series called 'Dark Side of the Ring', which Foley narrated.

Scientists will forever be uncertain as to Benoits motive, however, WWE attorney Jerry McDevitt, appearing on Live with Dan Abrams on July 17, 2007, said that Benoit was prescribed testosterone as part of a treatment for testosterone replacement therapy.

This surgery is seen as common medical practice for people who had used steroids in the past.

Foley later on in his social media post said: "I would love to see Nancy inducted into the WWE Hall of Fame - under whatever name or character her family and WWE collectively decide.

"For her work as Fallen Angel, I believe she deserves to be included. For her work as Woman during her first run in WCW when she feuded with Rick Steiner, managed Doom, and managed The 4 Horsemen - I believe she deserves to be included.

"For her run in ECW, and her second run with WCW - where she helped create a fascinating angle that blurred the line between storyline and reality - I believe she deserves to be included.

Inducting Nancy Toffoloni into the WWE Hall of Fame is the right thing to do. Let us remember her, and define her for who she was and what she did in life.

With Foleys status in the company, it is thought his request will be seriously considered.

The rest is here:
WWE news: Mick Foley wants Nancy Benoit inducted into Hall of Fame - GIVEMESPORT

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Testosterone Replacement Therapy Market Overview, Top Companies, Region, Application and Global Forecast by 2026 – Latest Herald

Posted: April 27, 2020 at 9:49 am

Acerus Pharmaceuticals

Global Testosterone Replacement Therapy Market Segmentation

This market was divided into types, applications and regions. The growth of each segment provides an accurate calculation and forecast of sales by type and application in terms of volume and value for the period between 2020 and 2026. This analysis can help you develop your business by targeting niche markets. Market share data are available at global and regional levels. The regions covered by the report are North America, Europe, the Asia-Pacific region, the Middle East, and Africa and Latin America. Research analysts understand the competitive forces and provide competitive analysis for each competitor separately.

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Testosterone Replacement Therapy Market Region Coverage (Regional Production, Demand & Forecast by Countries etc.):

North America (U.S., Canada, Mexico)

Europe (Germany, U.K., France, Italy, Russia, Spain etc.)

Asia-Pacific (China, India, Japan, Southeast Asia etc.)

South America (Brazil, Argentina etc.)

Middle East & Africa (Saudi Arabia, South Africa etc.)

Some Notable Report Offerings:

-> We will give you an assessment of the extent to which the market acquire commercial characteristics along with examples or instances of information that helps your assessment.

-> We will also support to identify standard/customary terms and conditions such as discounts, warranties, inspection, buyer financing, and acceptance for the Testosterone Replacement Therapy industry.

-> We will further help you in finding any price ranges, pricing issues, and determination of price fluctuation of products in Testosterone Replacement Therapy industry.

-> Furthermore, we will help you to identify any crucial trends to predict Testosterone Replacement Therapy market growth rate up to 2026.

-> Lastly, the analyzed report will predict the general tendency for supply and demand in the Testosterone Replacement Therapy market.

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Table of Contents:

Study Coverage: It includes study objectives, years considered for the research study, growth rate and Testosterone Replacement Therapy market size of type and application segments, key manufacturers covered, product scope, and highlights of segmental analysis.

Executive Summary: In this section, the report focuses on analysis of macroscopic indicators, market issues, drivers, and trends, competitive landscape, CAGR of the global Testosterone Replacement Therapy market, and global production. Under the global production chapter, the authors of the report have included market pricing and trends, global capacity, global production, and global revenue forecasts.

Testosterone Replacement Therapy Market Size by Manufacturer: Here, the report concentrates on revenue and production shares of manufacturers for all the years of the forecast period. It also focuses on price by manufacturer and expansion plans and mergers and acquisitions of companies.

Production by Region: It shows how the revenue and production in the global market are distributed among different regions. Each regional market is extensively studied here on the basis of import and export, key players, revenue, and production.

About Us:

Market Research Intellect provides syndicated and customized research reports to clients from various industries and organizations with the aim of delivering functional expertise. We provide reports for all industries including Energy, Technology, Manufacturing and Construction, Chemicals and Materials, Food and Beverage and more. These reports deliver an in-depth study of the market with industry analysis, market value for regions and countries and trends that are pertinent to the industry.

Contact Us:

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Market Research Intellect

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Tags: Testosterone Replacement Therapy Market Size, Testosterone Replacement Therapy Market Growth, Testosterone Replacement Therapy Market Forecast, Testosterone Replacement Therapy Market Analysis

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Kathy Lettes new book Husband Replacement Therapy has an empowering message for women over 50 – 7NEWS.com.au

Posted: April 27, 2020 at 9:49 am

Kathy Lette has spent 40 years making us laugh out loud with her side-splitting stories.

The Aussie author has now penned 19 books, including the controversial teen classic Puberty Blues - which was turned into a feature film and TV show.

Watch the full story above

Now, the author has released a saucy new novel about breaking free at 50, the power of female friendship, and proving that women only get better with age.

This is a book about women ageing disgracefully, Lette said.

Its saying to women its okay for once in your life to have some fun - because so many women are tethered to the kitchens by our aprons and heartstrings.

But when the kids start to leave home, women can finally put themselves first for a change.

I thought at my age, Id be sitting at home knitting my own bus pass - but I dont feel like that at all. I feel like swinging off a chandelier with a toyboy between my teeth.

So this is a book thats all about that, and saying to women, have fun and be frivolous. Enjoy yourself. Its a comedy with a lot of girl talk.

The novel, titled HRT, Husband Replacement Therapy, also touches on divorce.

The majority of divorces in Australia now are actually initiated by women, Lette said.

The two chief times are when the last kid finishes school or when the husband retires.

More on 7NEWS.com.au

As a woman ages, her estrogen drops and her testosterone comes up - so she gets a little bit more selfish and more like a bloke.

For men, its the opposite - they want to stay at home and nest, but the womans like, Ive nested. Theres a real difference between what older men and women they want, so I thought it would be an interesting area to explore.

I dont see divorce as a failure - I just see it as a change. It is okay to have a second act.

Kathy Lettes new book is out now - find out more here.

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Global Human Immunoglobulin (pH4) for Intravenous Injection (COVID-19) Market to Surpass US$ 99,772.2 Million by 2027 – CMI – GlobeNewswire

Posted: April 24, 2020 at 3:47 am

SEATTLE, April 23, 2020 (GLOBE NEWSWIRE) -- According to Coherent Market Insights, the global human immunoglobulin (pH4) for intravenous injection (COVID-19) market is estimated to be valued at US$ 43,205.8 million in 2020, and is expected to exhibit a CAGR of 12.7% during the forecast period (2020-2027).

Key Trends:

Key trends in the market include viral disease outbreaks, the increasing prevalence of chronic lymphocytic leukemia, and demand for immune globulin products in the market.

According to the American Cancer Society around 60,530 new cases of leukemia will be diagnosed in the U.S in 2020 out of which 21,040 new cases will be of chronic lymphocytic leukemia (CLL).

Similarly, according to the Cancer Research UK, around 3,500 new cases of chronic lymphocytic leukemia (CLL) were diagnosed in the U.K in 2017.

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Moreover, the growing demand for immune globulin (IG) products is expected to drive the human immunoglobulin (ph4) for intravenous injection (COVID-19) market growth. For instance, on August 12, 2019, the U.S. Food and Drug Administration (FDA) confirmed that demand for immune globulin products has increased in recent years and there is a shortage of Immune Globulin (Subcutaneous) (IGSC) and Immune Globulin (Intravenous) (IGIV) products in the U.S. The U.S. Food and Drug Administration is working closely with manufacturers such as Asceniv, Bivigam, Octagam, Panzyga, Privigen and others of various immune globulin (intravenous) (IGIV) products to help mitigate the supply situation for IG products.

Key Market Takeaways:

Key players operating in market are

Takeda Pharmaceutical Company Limited, Baxter International Inc., CSL Behring, Bayer AG, Grifols, S.A., Octapharma AG, Shanghai RAAS Blood Products Co., Ltd., Hualan Biological Engineering Inc., China Biologic Products, Inc., Sichuan Yuanda Shuyang Pharmaceutical Co., Ltd., Boya Bio-Pharmaceutical Group Co., Ltd., ADMA Biologics, Inc., and Sinopharm Group Co., Ltd.

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Market Segmentation:

Related Topics:

HEALTHCARE CONTRACT RESEARCH OUTSOURCING MARKET

Healthcare Contract Research Outsourcing is conducted by pharmaceutical and medical device sectors for development of new drugs and medical devices. Clinical trials form the key part of pharmaceutical drug and medical device development and in the current scenario clinical trials are conducted across multiple locations in various geographies. Increasing cost and time required for drug development is expected to propel growth of the global healthcare contract research outsourcing market over the forecast period.

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ANDROGEN REPLACEMENT THERAPY MARKET

Androgen replacement therapy (ART), often referred to as testosterone replacement therapy (TRT), is a form of hormone therapy, in which androgens, often testosterone, are replaced. ART is often prescribed to counter the effects of male hypogonadism. It typically involves the administration of testosterone through injections, skin creams, patches, gels, or subcutaneous pellets. Testosterone replacement therapy is a promising technology for improving symptoms of hypogonadism and to raise the testosterone level.

Read more @ https://www.coherentmarketinsights.com/market-insight/androgen-replacement-therapy-market-3787

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Global Human Immunoglobulin (pH4) for Intravenous Injection (COVID-19) Market to Surpass US$ 99,772.2 Million by 2027 - CMI - GlobeNewswire

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Testosterone Replacement Therapy Market Analysis by Size, Share, Top Key Manufacturers, Demand Overview, Regional Outlook And Growth Forecast to 2026…

Posted: April 22, 2020 at 8:47 pm

Acerus Pharmaceuticals

Global Testosterone Replacement Therapy Market Segmentation

This market was divided into types, applications and regions. The growth of each segment provides an accurate calculation and forecast of sales by type and application in terms of volume and value for the period between 2020 and 2026. This analysis can help you develop your business by targeting niche markets. Market share data are available at global and regional levels. The regions covered by the report are North America, Europe, the Asia-Pacific region, the Middle East, and Africa and Latin America. Research analysts understand the competitive forces and provide competitive analysis for each competitor separately.

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Global Testosterone Replacement Therapy Market Regions and Countries Level Analysis

The regional analysis is a very complete part of this report. This segmentation highlights Testosterone Replacement Therapy sales at regional and national levels. This data provides a detailed and accurate analysis of volume by country and an analysis of market size by region of the world market.

The report provides an in-depth assessment of growth and other aspects of the market in key countries such as the United States, Canada, Mexico, Germany, France, the United Kingdom, Russia and the United States Italy, China, Japan, South Korea, India, Australia, Brazil and Saudi Arabia. The chapter on the competitive landscape of the global market report contains important information on market participants such as business overview, total sales (financial data), market potential, global presence, Testosterone Replacement Therapy sales and earnings, market share, prices, production locations and facilities, products offered and applied strategies. This study provides Testosterone Replacement Therapy sales, revenue, and market share for each player covered in this report for a period between 2016 and 2020.

Why choose us:

We offer state of the art critical reports with accurate information about the future of the market.

Our reports have been evaluated by some industry experts in the market, which makes them beneficial for the company to maximize their return on investment.

We provide a full graphical representation of information, strategic recommendations and analysis tool results to provide a sophisticated landscape and highlight key market players. This detailed market assessment will help the company increase its efficiency.

The dynamics of supply and demand shown in the report offer a 360-degree view of the market.

Our report helps readers decipher the current and future constraints of the Testosterone Replacement Therapy market and formulate optimal business strategies to maximize market growth.

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Table of Contents:

Study Coverage: It includes study objectives, years considered for the research study, growth rate and Testosterone Replacement Therapy market size of type and application segments, key manufacturers covered, product scope, and highlights of segmental analysis.

Executive Summary: In this section, the report focuses on analysis of macroscopic indicators, market issues, drivers, and trends, competitive landscape, CAGR of the global Testosterone Replacement Therapy market, and global production. Under the global production chapter, the authors of the report have included market pricing and trends, global capacity, global production, and global revenue forecasts.

Testosterone Replacement Therapy Market Size by Manufacturer: Here, the report concentrates on revenue and production shares of manufacturers for all the years of the forecast period. It also focuses on price by manufacturer and expansion plans and mergers and acquisitions of companies.

Production by Region: It shows how the revenue and production in the global market are distributed among different regions. Each regional market is extensively studied here on the basis of import and export, key players, revenue, and production.

About Us:

Market Research Intellect provides syndicated and customized research reports to clients from various industries and organizations with the aim of delivering functional expertise. We provide reports for all industries including Energy, Technology, Manufacturing and Construction, Chemicals and Materials, Food and Beverage and more. These reports deliver an in-depth study of the market with industry analysis, market value for regions and countries and trends that are pertinent to the industry.

Contact Us:

Mr. Steven Fernandes

Market Research Intellect

New Jersey ( USA )

Tel: +1-650-781-4080

Tags: Testosterone Replacement Therapy Market Size, Testosterone Replacement Therapy Market Growth, Testosterone Replacement Therapy Market Forecast, Testosterone Replacement Therapy Market Analysis

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Testosterone Replacement Therapy Market Analysis by Size, Share, Top Key Manufacturers, Demand Overview, Regional Outlook And Growth Forecast to 2026...

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Given Alex Rodriguez’s history with doping scandals, should he be allowed to own New York Mets? – MEAWW

Posted: April 22, 2020 at 8:46 pm

This week, reports emerged that former baseball player Alex Rodriguez and his fiance Jennifer Lopez are eyeing a bid to buy the Major Leagues Baseball (MLB) team, New York Mets. However, with Rodriguez's extensive history with using performance-enhancing drugs, should such a sale be allowed?

In an earlier report, we had written that Rodriguez had opened up to 'The Tonight Show' host Jimmy Fallon about his inclination towards launching a future bid for the Mets and also confessed how he grew up a Mets fan before winning a world series with the Yankees. "I will say this, if the opportunity came up (to buy the Mets), I would certainly look at it," he told Fallon. He also went on to say how the 1986 championship-clinching game was one the best nights of his life after the birth of his daughters.

While Rodriguez now has a thriving career as a baseball analyst, commentator and host and enjoys the limelight coming from being engaged to actor, dancer and singer Jennifer Lopez it is difficult to erase his baseball career. Even though he was once dubbed the greatest baseball player of his generation, his achievements were marred by cheating scandals.

His playing career had resulted in one World Series title, three MVP awards, 14 All-Star appearances, 696 home runs and earnings of $452M the most in the history of Major League Baseball.

The Biogenesis scandal, which resulted in Rodriguez's suspension, broke out in 2013 and was the biggest baseball performance-enhancing drugs (PED) scandal, but Rodriguez had been caught using performance-enhancing drugs much before that.

In July 2007, former outfielder and steroid-user Jose Canseco called Rodriguez a "hypocrite" and alleged that the latter was using steroids something Rodriguez vehemently denied.

In 2009, Sports Illustrated reported that Rodriguez had tested positive for two anabolic steroids, testosterone and Primobolan, during his 2003 season playing for the Texas Rangers. This was the same season in which he captured his first American League Most Valuable Player award, broke 300 career home runs (hitting 47 that year) and earned one of his 10 Silver Slugger Awards.

The same year, Rodriguez told ESPN that he had used PEDs when he first started out, stating, "When I arrived in Texas in 2001, I felt an enormous amount of pressure. I felt like I had all the weight of the world on top of me and I needed to perform, and perform at a high level every day."

In 2003, as the result of a collectively bargained union agreement, there was no penalty or punishment for a positive test during an anonymous drug survey and mandatory drug testing only began in 2004 after more than 5% of the samples taken from players in 2003 came back positive. In 2013, the New York Times alleged that Rodriguez tested positive for a banned stimulant in 2006.

It was the Biogenesis scandal that broke out the same year that catapulted the MLB, Rodriguez and other players of note to infamy. A disgruntled former employee of Biogenesis in America a health clinic briefly operating in Coral Gables, Florida, specializing in weight loss and hormone replacement therapy released records of the clinic's real business. These records showed that players such as Rodriguez, Melky Cabrera, Bartolo Coln, Ryan Braun and Nelson Cruz were getting access to PEDs, thanks to an unlicensed doctor.

Over the next two months, MLB suspended 14 players. Meanwhile, penalties for getting caught increased. First-time offenses went from 50 to 80 games, while second-time offenses went from 100 games to an entire season. Any offender caught doping is now ineligible for that year's playoffs, no matter when the infraction occurs.

For a long time, Rodriguez insisted he was innocent and even alleged that the MLB engaged in a "witch hunt" to get him out of baseball when he sued the league in 2013. Rodriguez and his team voluntarily dropped the suit in February 2014.

In 2019, Billy Corben's documentary on the scandal titled 'Screwball' released and oddly, news of Rodriguez's engagement to Lopez broke a day after the trailer for the documentary released. In an interview with Rolling Stone, Corben described the scandal as Florida f**kery distilled like freebasing Florida f**kery and crony capitalism".

Although Rodriguez has since apologized for his role in the Biogenesis scandal, Corben was suspicious of Rodriguez's image rehab. Corben told Rolling Stone, "This is the guy who was never beloved. He was booed by his own fans, for crying out loud. Without so much as a mea culpa tour, he hasnt rehabilitated his image, hes created an entirely new one that never existed before."

In August 2013, Rodriguez was suspended through the 2014 season (211 games at the time of the decision), but was allowed to play in 2013 pending his appeal of that decision. His suspension was upheld in January 2014 after being allowed to play in the 49 games between the decision and the hearing, technically reducing the suspension to 162 games. In July 2014, Rodriguez was sued by his lawyers for $380,000 in unpaid legal fees.

In November that year, it was revealed that Rodriguez had admitted to the Drug Enforcement Administration that he had used performance-enhancing drugs as early as January of the same year and Rodriguez got immunity from prosecution.

Many have also called into question MLB's handling of the Biogenesis scandal, suggesting that the MLB's actions were motivated to save face rather than to take serious action on the use of PEDs among players.

Given Rodriguez's lengthy history of association with PEDs, it stands to question whether the one-time-great baseball player ought to be given the power of owning an entire baseball team and whether the MLB would even allow it.

However, with Rodriguez's new image and with Lopez's name included in the deal, it stands to reason that the MLB would be okay with Rodriguez being one of the owners of the New York Mets, even if that may leave baseball lovers with a sour taste in their mouths.

As 'Screwball' filmmaker Corben said on the Biogenesis scandal, "When Alex was useful as a heel, he was the villain. When Bud Selig needed to salvage his own reputation as the steroid commissioner and was trying some kind of redemption and legacy-saving measures, Alex was the villain. And now that Bud Seligs gone, (current commissioner) Rob Manfred, who was responsible for this entirely botched, potentially illegal investigation of Biogenesis, ascends (within MLB) into a position of power and decides, "Oh, Alex is an ally." They let bygones be bygones now? Like after the s**tshow that they put each other through? It certainly goes to show how not legitimate MLBs concerns are about steroids and shooting up in baseball, because its obviously good for business."

Continued here:
Given Alex Rodriguez's history with doping scandals, should he be allowed to own New York Mets? - MEAWW

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Options to Increase Your Testosterone

Posted: April 21, 2020 at 9:48 pm

In the last 100 years, life expectancy for men has increased by 65 percent, according to the Centers for Disease Control and Prevention (CDC).

In 1900, men lived until about age 46. By 2014, that age jumped to 76. Theres no question that men are redefining what it means to be 50, 60, and 70 years old or older.

Regular exercise, a healthy diet, and adequate rest all help maintain energy and vitality in men over 50. But men are also turning to one of the most advanced aging solutions available. Over the last decade, testosterone use among middle-aged and senior men has become popular.

Testosterone is the hormone responsible for the development of male external genitalia and secondary sexual characteristics. Its produced by the testicles. Testosterone is important for maintaining:

Testosterone also contributes to vitality and well-being.

As men age, their bodies gradually produce less testosterone. This natural decline starts around age 30 and continues throughout the rest of a mans life.

Some men have a testosterone deficiency called male hypogonadism. This is a condition in which the body doesn't produce enough testosterone. It may be caused by problems in the:

Men at risk for this condition include those who have had an injury to the testicles or have HIV/AIDS. If youve gone through chemotherapy or radiation therapy, or had undescended testicles as an infant you are also considered at risk for hypogonadism.

Symptoms of male hypogonadism in adulthood include:

Doctors can determine if you have male hypogonadism through physical exams and blood tests. If your doctor detects low testosterone they may perform additional tests to determine the cause.

Treatment typically includes testosterone replacement therapy (TRT) in the form of:

TRT reportedly helps to:

However, scientists caution there isnt enough information to determine the safety of regular testosterone supplementation.

Many men experience changes as they age similar to the symptoms of hypogonadism. But their symptoms may not be related to any disease or injury. Some are considered a normal part of aging, such as:

The Mayo Clinic reports that TRT can help men with hypogonadism. The results are not as clear with men who have normal levels of testosterone or older men with decreasing testosterone levels. More rigorous studies are needed, according to the Mayo Clinic.

Studies are mixed on whether TRT is beneficial for normal men as they age. Some research has brought up serious risks with the therapy, particularly when taken long term. This has led doctors to be cautious about recommending it.

A large, 2010 meta-analysis of 51 studies looked at the safety of TRT. The report concluded that safety analysis of TRT is of low quality and fails to inform the public about potential long-term effects.

The Mayo Clinic cautions that TRT also may:

There are also risks involved in having low testosterone levels, such as:

Previously, there were concerns that TRT raised the risk of developing prostate cancer.

Most current data, including two reports in 2015, no longer supports a link between testosterone replacement and the development of 1) prostate cancer, 2) more aggressive prostate cancer, or 3) prostate cancer that returns after treatment.

If you have male hypogonadism or low testosterone, talk with your doctor about whether TRT may be a good option for you. Discuss the risks and benefits of TRT.

If you dont have hypogonadism, but youre interested in feeling more energetic and youthful. The following alternative methods may help increase your testosterone level without the use of hormone therapy.

One way to increase your testosterone levels is through TRT. Its especially effective if you have hypogonadism. Studies have not yet demonstrated the effectiveness of TRT in helping men with normal levels of testosterone or older men with decreasing testosterone levels due to aging.

Men who take TRT usually experience increased energy, a higher sex drive, and overall well-being. But its long-term safety hasnt been established.

There are a variety of lifestyle treatments involving exercise, diet, and sleep that have been shown to increase testosterone levels. Talk to your doctor about what may be best for you.

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Options to Increase Your Testosterone

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Testosterone Replacement Therapy Studies 2019

Posted: April 21, 2020 at 9:48 pm

2018 saw a plethora of reports on testosterone replacement therapy, health risks, studies, trials, and types of TRT. Here at HGH doctor, our hormone replacement physicians keep up on the latest research to ensure we provide the best quality care to our clients. Part of our focus is passing new information and studies forward to you here on our website.

The results of one study on middle-aged and older men focused on the best type of treatment for fat-free mass (FFM) and muscle strength response. Men participating in the study received either intramuscular testosterone injections, transdermal TRT, or a placebo.

Although all forms of testosterone therapy showed positive improvements in FFM, total body strength, and lower and upper extremity strength, the changes seen were 3 to 5 times greater in the men who received testosterone injections rather than transdermal TRT. [1]

Testosterone therapy studies such as this one help our doctors choose the appropriate treatment for each person.

The Testosterone Therapy Trials in elderly men consisted of seven coordinated trials looking at the following areas:

We will report on these, as well as other trials and studies in this article.

Testosterone studies shed light on the benefits and safety of using testosterone replacement therapy.

For years, doctors steered men with or at greater risk of developing prostate cancer away from TRT. Even if a male had all the signs of low testosterone, many doctors believed that treatment with testosterone therapy would increase prostate cancer dangers. Luckily, there has been much research done in this area, showing the safety and benefits of TRT following prostate cancer treatment. Also, men who suffer from prostate enlargement or prostate cancer risks can also safely use testosterone therapy.

In the most recent testosterone replacement therapy studies, mounting evidence points to the safety of testosterone without reducing the risk of prostate cancer.

In a pooled analysis of 18 testosterone replacement therapy recent studies on 3,886 men diagnosed with prostate cancer, and 6,439 in the control group, there was no association between testosterone levels, DHT, and prostate cancer. [2, 3]

In a 2017 report, the Registry of Hypogonadism in Men reported that there was no increase in the odds of developing prostate cancer with the use of TRT. [4]

A 2013 study of men who underwent prostatectomy for prostate cancer found no increased risk of prostate cancer following testosterone therapy. [5]

In 2015, a study of men who underwent radiation therapy for prostate cancer followed up by testosterone therapy showed only a minor increase in serum PSA and a low rate of biochemical recurrence. [6]

Based on the current research, testosterone replacement therapy shows positive benefits for improving quality of life and well-being in men treated for prostate cancer.

With a multitude of testosterone replacement therapy studies reversing the prior concerns about cardiovascular risk, many men can improve their quality of life with TRT to treat the symptoms of hypogonadism.

Testosterone supports heart health through the production of red blood cells needed for circulation. Additionally, testosterone improves nitric oxide production crucial for proper insulin function and blood flow.

Nitric oxide is crucial to heart health and is made by the endothelium the lining of the blood vessels. Testosterone helps to lower LDL cholesterol to reduce the plaque clogging the arteries.

In 2017, a look at testosterone and the heart showed that low levels of testosterone might increase risk factors for metabolic syndrome, coronary artery disease (CAD), and type 2 diabetes. Testosterone replacement therapy helps to improve myocardial ischemia in males diagnosed with CAD. TRT also increases exercise capacity in men with congestive heart failure (CHF). Testosterone aids in weight loss and improving serum glucose levels and insulin resistance. This study reports that TRT reduces the risk of mortality in testosterone deficient men. [8]

Testosterone has many benefits for heart health, improving circulation, and reducing the risk of cardiovascular disease.

The study duration of one year consisted of receiving either testosterone gel or a placebo. Three different questionnaires every three months assessed sexual function. Results of the study showed that TRT had significant improvements for 10 out of 12 measures of sexual activity. [9, 10]

Testosterone replacement therapy studies for men with urinary symptoms such as urinary frequency, weak stream, urgency, straining to void, and other issues have found that benign prostatic hyperplasia (BPH) can impact urinary health. Prostate enlargement often occurs as men age, along with a decline in testosterone levels. Urinary issues can impact not only quality of life, but also overall health. Treatment with testosterone therapy has been shown to decrease nocturia (nighttime voiding) and improve urinary symptoms. [11]

A 2017 study of more than 650 men showed that testosterone therapy reduces weak urinary stream, nighttime waking to urinate, incomplete emptying of the bladder, and frequent urination. Additional benefits were found in erectile functions and quality of life. [12]

Testosterone has benefits for improved sexual functions as well as urinary health.

Reviewing testosterone replacement therapy studies allows our doctors to incorporate the latest research into patient treatment protocols. Low testosterone is frequently associated with the following medical conditions:

In the Physical Function Trial for men with hypogonadism, the focus was on walking distance as a measurement of testosterone benefits. TRT increased the fraction of distance walked, and the absolute increase in distance walked in 6 minutes.[13]

The Vitality Trial measured only the Functional Assessment of Chronic Illness Therapy fatigue scale, and while the results were not significant, the overall findings from the entire testosterone trials whose positive improvements on vitality, mood, and depression symptoms. However, a 2018 report found that testosterone replacement therapy reduces depressive symptoms except in individuals with major depressive disorder.[14]

The results of the Anemia Trials from these studies on testosterone therapy were extremely positive. In both men with explained and unexplained anemia, there was a considerable increase in hemoglobin concentration. The increase was associated with a significant change in the impression of vitality and general health in these men.

The Bone Trial purpose was to determine if TRT in older men could increase volumetric bone mineral density (vBMD) and bone strength. The outcome showed a total increase in vBMD of the trabecular bone in the spine as well as the whole bone vBMD. Hip strength also improved with TRT. Treatment with testosterone therapy could result in reduced risk of bone fractures for older men.

A surprising outcome of the Testosterone Therapy Trials is that there was not much in the way of cognitive benefits. However, other studies offer different findings. A double-blind, placebo-controlled study found modest improvement in global cognition.[15]

Testosterone replacement therapy can benefit physical ability, red blood cell production, and bone density.

Based on the many testosterone replacement therapy studies available for review today, we believe that the safe and supervised use of TRT can offer many benefits for middle-aged and older men. The key factor here is the need to engage in proper diagnostic testing for low testosterone and remain under doctor-supervision while receiving testosterone therapy.

To date, there is less research on testosterone therapy for women with Low T. A 2014 review of 20 randomized, placebo-controlled trials shows positive benefits for sexual response, sexual desire, frequency of activity, and overall satisfaction and orgasm. The majority of research does not show a connection between testosterone and breast cancer, making TRT a possible menopausal treatment for women who cannot use estrogen therapy. [16]

A 2015 report discusses the possible cardiovascular effects of testosterone for women, as well as enhancements for cognitive performance and musculoskeletal health in postmenopausal women. [17]

Regarding future testosterone therapy studies, 2019 should also be a promising year. HGH Doctor looks forward to keeping you informed of the latest research. At this time, we believe testosterone therapy to be extremely safe for men and women following proper diagnostic procedures.

For more information on testosterone replacement therapy, please contact our hormone clinic for a free and confidential consultation.

Research has shown testosterone replacement therapy to be extremely safe and highly effective for treating symptoms of Low T.

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Testosterone Replacement Therapy Studies 2019

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