SILVER SPRING, Md., Feb. 13, 2020 /PRNewswire/ -- The following quote is attributed to Janet Woodcock, M.D., director of the FDA's Center for Drug Evaluation and Research:

"Public health and safety of drugs that Americans rely on is a top priority at the FDA both before and after approval. We're taking steps to notify the public about a particular weight-loss medication and have requested that the company voluntarily withdraw the product from the market because our review of the full clinical trial results shows that the potential risk of cancer associated with the drug outweighs the benefit of treatment. The company has submitted a request to voluntarily withdraw the drug.

"As noted in a new Drug Safety Communication issued today, patients should stop using the medication Belviq and Belviq XR (lorcaserin) and talk to their health care professionals about other treatment options for weight loss.Health care professionals should stop prescribing and dispensing Belviq and Belviq XR.

"The FDA is not recommending special screening for patients who have taken Belviq. Standard screening recommendationsfor cancer should be implemented for any patient, regardless of prior Belviq treatment.

"The agency's actions follow our alert to the public earlier this year about the possible risk of cancer associated this medication based on preliminary analysis of the clinical trial data.

"We will continue to track safety issues with medications on the market and use science and data as our guide to act quickly when we have determined that the risks associated with drugs are greater than the benefits of treatment."

Additional Resources:

Media Contact:Monique Richards, 240-402-3014Consumer Inquiries: Email, 888-INFO-FDA

The FDA, an agency within the U.S. Department of Health and Human Services, protects the public health by assuring the safety, effectiveness, and security of human and veterinary drugs, vaccines and other biological products for human use, and medical devices. The agency also is responsible for the safety and security of our nation's food supply, cosmetics, dietary supplements, products that give off electronic radiation, and for regulating tobacco products.

SOURCE U.S. Food and Drug Administration

http://www.fda.gov

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FDA In Brief: FDA Requests Voluntary Withdrawal of Weight-Loss Medication After Clinical Trial Shows an Increased Occurrence of Cancer - PRNewswire

A inspirational Carluke man has an important piece of advice for people struggling to lose weight: Believe in yourself.

Gordon Davidson had been miserable after piling on the pounds and reaching his heaviest weight of 18 stone.

The 62-year-old could no longer enjoy his summer holidays and was struggling to walk around without getting breathless.

I never had the belief I could lose weight, said Gordon.

But Weight Watchers, attending workshops, walking and regular activity has now given me a belief in myself.

If I can do it, then others can do it. Believe in yourself.

It was after returning from a trip abroad that Gordon realised he needed to take some serious action to get back in shape.

While his holiday should have been a time to relax and enjoy himself, walking around sightseeing was difficult because he was so unfit and all the holiday food led to more weight gain.

Gordon said: I didnt enjoy my time abroad and when I came home and saw a picture of myself, I decided that it was finally time to do something about it.

I had been eating all the wrong things like lots of puddings, biscuits and cakes, so its no wonder my weight had gone up to 18st.

It was the heaviest I had ever been.

I was eating too much and portions were big, too big!

Gordon joined the Weight Watchers club that meets at Wishaw Volunteer Centre, and was warmly welcomed by slimming coach Barbara Graham.

She made me feel instantly at ease, said Gordon.

I settled into the my Weight Watchers plan quickly and easily and loved the choice of zero smartpoint foods, which really helped to fill me up without using too many points. I learned that I could eat lots of foods if I just changed what I was eating.

I was always satisfied and never hungry.

I was able to enjoy alcohol at the weekends and the occasional dessert, and I could mix and match different foods.

My weekly workshop was really beneficial and we all helped to motivate each other.

Now 70lbs lighter, I am fitter and healthier than ever before.

Gordon now walks regularly throughout the week and loves to play badminton to stay fit.

His trouser size has dropped from a 38-inch to 32-inch waist, and hes ditched XXL tops for a standard medium size.

Five stone lighter and in much-improved health, Gordon is looking forward to jetting off and enjoying his holidays again.

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Man who struggled to walk has life back thanks to huge weight loss - Daily Record

The Greene County shooting that left two people dead Wednesday outside a million-dollar home near Yellow Springs involved a celebrity nutritionist who appeared on TV shows, his Hollywood stunt woman ex-wife and her current husband.

A man who identified himself as Robert Lindsey Duncan can be heard in a 911 call alerting law enforcement that he had shot two people who he says came onto his property and threatened to kill him and his wife.

I shot them, they came up to our window and had a gun pointed at my wifes head, Duncan told a dispatcher while asking for authorities to get to his 3443 Grinnell Road home as quickly as possible.

Duncan is the founder and CEO of Genesis Today who appeared on the Dr. Oz Show and The View nearly a decade ago to talk about weight loss.

A phone message to Duncan wasnt returned Thursday evening.

Greene County Sheriff Gene Fischer declined to identify Duncan, who has not been charged with any crime.

FIRST REPORT:Shootout near Yellow Springs could have been ambush, sheriff says

Greene County Sheriff Gene Fischer identified the dead woman as Cheryl Sanders, 59, who was a spokeswoman and stunt woman who appeared on the cover of Healthy Living Magazine. Her current husband, Robert Reed Sanders, 56, also was killed in the shooting.

Sanders wrote online that she moved from martial arts and kickboxingto a career as a stunt womanin the 1980s. She said was the stunt double for Brooke Shields, Kathleen Turner, Sharon Stone and other A-list actresses.

Court records show that Duncan and Cheryl Sanders signed a prenuptial agreement in 1999, were married, then divorced in 2009.

Since the divorce, the records indicate their relationship remained sour.

According to a court filing in 2016, Duncan sued Cheryl Sanders and Robert Sanders for defamation, slander, libel and other accusations.

Defendant Cheryl provided a written statement to both boards of Genesis Pure and Genesis Today, as well as non-board members, employees and various members of the plaintiffs family, the suit says. This statement accused the Plaintiff of false, malicious, defamatory and vicious accusations, which defamed both the plaintiff and Genesis Today and Genesis Pure.

Exactly what was said isnt spelled out in the lawsuit. The lawsuit claims Duncan was subjected to numerous attempts at extortion and harassment.

Motions in the lawsuit have been filed as recently as September of last year. The most recent action came in November, according to online court records, when a sub or withdraw of counsel took place. The case status is labeled pending.

The Dayton Daily News has requested the documents in the case. The online court records list David Gottfried as the Sanders attorney. A message left at his office wasnt returned.

Duncans wife, who is identified as Molly in the 911 call, tells dispatchers during that call that Cheryl Sanders has been trying to kill them for years.

Fischer said during a press conference Thursday that his office is still looking at whether the shooting was a planned ambush of Duncan and his wife. He said the Sanderses were driving a car with fictitious Ohio temporary plates. He also said the two had set up a camera to view the incident.

Fischer also said during the press conference that Duncan had alerted his office about five years ago that he feared Cheryl Sanders had hired someone to kill him. Fischer said extra patrols were dispatched around the home at that time.

He said he didnt know what the motive of the shooting was but did say money could have played a role.

Money can be the root of all evil, he said. But I cant say its money, Im not sure exactly why this happened. Thats whats the investigation is for.

Officials said the investigation will take a long time and will be presented to a grand jury for review.

According to a Federal Trade Commission press release from 2015, Duncan and his companies faced charges from the commission for, in part, deceptively touting the supposed weight-loss benefits of green coffee bean extract through a campaign that included appearances on The Dr. Oz Show, The View, and other television programs.

The commission accused Duncan of misleading consumers by saying that green coffee bean extract would help them lose as much as 17 pounds and 16 percent of body fat in 12 weeks, without diet or exercise.

RELATED:What we know today about the double-fatal shooting near Yellow Springs

The commission said that claim wasnt true.

a clinical study does not show that GCBE causes substantial weight loss and fat loss, or rapid and substantial weight loss and fat loss, including 17 pounds in 12 weeks and 16 percent of body fat in 12 weeks, without diet or exercise, the complaint says.

In a settlement, Genesis Today, Pure Health LLC and Duncan agreed to pay $9 million to the commission and were barred from making deceptive claims about the health benefits of any dietary supplement or drug product, the press release says.

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Greene County 911 caller: They came up to our window and had a gun pointed at my wifes head&rsqu - Dayton Daily News

Thirty years ago, fat was the main diet demon and carbs fuelled the day with toast or cereal the standard breakfast, a simple sandwich at lunchtime. Back then, dinner wasn't dinner unless a potato or some rice or pasta graced the plate.

Now there are few food groups as tainted as the humble carbohydrate, especially when it comes to weight loss. So while many an extreme diet bans carbs completely, are they really that bad for us? Are some better than others? And how can you strike the right balance for you?

Carbohydrates are one of the three macro-nutrientsthat give the body energy (the other two are protein and fat). Carbs are primarily found in plant-based foods, including bread, rice, breakfast cereal, fruits, starchy vegetables and sugars and offer 17kJ (4 calories) of energy per gram.

The simplest form of carbohydrate is glucose, and carbohydrates range from mixes of simple sugars to hundreds of individual sugars that form more complex carbohydrates, such as breads and cereals.

Carbohydrates can also be grouped according to their glycaemic index. The glycaemic index refers to how quickly or how slowly a carbohydrate releases glucose into the bloodstream. Low GI foods such as wholegrains release the glucose relatively slowly, compared to higher GI foods such as white bread and rice.

Generally speaking, natural sources of carbohydrate, as found in whole, natural foods like fruit, starchy vegetables, and legumes, and wholegrains such as oats, barley and quinoa, are the best carbs to include in the diet on a daily basis.

When carbs are consumed as wholefoods, we get the added benefit other key nutrients, including fibre, vitamins and minerals. Wholegrain and low GI natural sources of carbohydrate are also far less likely to be overconsumed the way refined carbohydrates found in processed cereals, white breads, snack food, biscuits, juices and sugars are.

The amount of carb you need will depend largely on how active you are. If you spend all day on your feet and are already quite slim, you will need more than someone who sits all day does minimal exercise. And similarly, on days you train for an hour or more, you will need more than on a sedentary day when you barely leave the house.

Without shifting to a complete 'low carb' or keto approach, where carbs equate to less than 20 per cent of total calories or just 50-80g of total carbohydrates per day, the average adult will require 30-50 per cent of their daily calories from carbohydrates (you can see this is a wide range), equating to roughly 80-200g of carbohydrates each day, or 1-3 half cup serves at each meal.

As carbohydrate is the primary fuel for the muscles, it is a common belief that eating fewer carbs means that you automatically burn a greater amount of fat. While this is somewhat true, as the body prefers to burn carbs in the form of glucose as its primary energy source, if carbs are restricted to a great enough extent, even though the body will shift to burning fat it will also slow metabolic rate over time. This means that initially you will get good results from a strict low-carb approach, but over time metabolic rate will reduce and the body will begin burning fewer calories as a result. This effect can be observed in individuals who have great success initially using a low-carb diet but who find it difficult to maintain once they return to their usual carbohydrate intake.

The strongest sign that you're eating too much carbohydrate is if you're gaining weight, or not losing weight despite making a concerted effort to eat less and exercise. The easiest way to count your own carbs is to use an online monitoring app such as 'myfitnesspal'.

While extremely low-carb diets, or less than 50g of total carbs a day will support ketosis and rapid weight loss, for those not in keto, it is possible to eat too few carbs for the amount of activity you are doing.

Signs your carbs may be a little on the low side include constant sugar cravings and hunger and an inability to lose weight despite eating less and exercising more. This may suggest you need a little more carbs to successfully burn body fat. The minimum amount of carbs someone not in keto will require is roughly 80-100g plus another 20-30g for every hour of exercise.

Naturally every food that contains carbohydrates has a different amount and generally larger serves for example, larger slices of bread have more than smaller slices. As a general rule of thumb, cup of carbohydrate or one piece of fruit has about 20g of carbs per serve. For a more accurate analysis, simply check 'carbs per serve' on nutrition panels or use a monitoring program such as 'myfitnesspal'.

So carbs are not bad for us, rather it tends to be the types of carbs we commonly choose or are served. Large slices of sourdough or Turkish bread, the white rice in sushi and large serves of noodles and fries at night are when we get our carbs wrong.

On the other hand, fruit, vegetables and controlled portions of wholegrains have plenty to offer the key is to stick to natural, whole unprocessed carbs when you can. And if your goal is weight loss, keep a close eye on how much total carbohydrate you are consuming each day.

Susie Burrell is a leading Australian dietitian and nutritionist, founder of Shape Me, and prominent media spokesperson, with regular appearances in both print and television media commenting on all areas of diet, weight loss and nutrition.

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Everything you need to know about carbs - 9Honey

Pop singer Adele has been making news lately for her dramatic weight loss. The singer born in the United Kingdom lost 120 pounds, all in the last year.

And now new photos of Adele in yoga pants: that she goes viral again.

Fans have noticed that while Adele has lost a lot of weight, she still maintains an hourglass figure.

Here is the image that is making it viral

On Wednesday, the paparazzi saw Adele, 31, and she looked thinner than ever when she left Los Angeles in black sportswear.

Twitter burst quickly. Not because of the weight loss, but because of the weight he retained, in the area of the hips and buttocks. The singer is called PAWG, or "a white girl **".

Here are some comments from Twitter, taken shortly after the images appeared online:

Adele Trynna be a PAWG. OK

ADELE A PAWG??!?!

I Adele a pawg ok or am i stumbling?

Adele it's definitely good PAWG lmao

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Adele lost weight, but not in the hips or in the butt: Twitter calls her a & # 39; PAWG & # 39 ;! - Up News Info

sourceTonal

Advertised as the worlds most intelligent home gym, Tonal is a digital touchscreen that mounts on your wall and promises a full-body workout and personal training from the comfort of your living room.

Though the tech debuted more than a year ago, in August 2018, its been expanding since and generated more buzz at this years Consumer Electronics Show.

Two arm-like appendages extend from the machine which, combined with a variety of attachable hands, allow you to push, pull, and hoist up to 200 pounds worth of digital weight, which is provided via electromagnetic resistance.

The price tag, at $2,995 and up, isnt cheap, but neither is a traditional home gym, since racks and barbells can easily run hundreds of dollars.

The result is like having a full gyms worth of equipment, in one sleek, efficient package. If it sounds too good to be true, I thought so too. But after trying Tonal out for myself at the companys Manhattan showroom, I came around to believe its one of the coolest fitness tech innovations Ive seen in a while.

Heres what I liked most about Tonals high-tech equipment and programming, and why its exciting even if the cost makes it out of reach for most everyday gym-goers.

For Tonals arms to provide so much digital weight, computer chips generate an electromagnetic field and magnets allow you to push or pull against that field, making it feel like actual weight.

The multi-directional movement of those arms, combined with attachments such as handles and a barbell, allow you to incorporate that resistance into the same strength-training movement you might do at the gym, such as bench presses, curls, squats, cable pulls, and more.

For fitness enthusiasts like me, the benefits of this are obvious, since it condenses bulky traditional gym equipment like a squat rack, cable machines, and heaps of dumbbells or kettlebells into one convenient package that fits on your wall. This is particularly exciting in New York, where tiny apartments and 5th floor walkups make it tricky to haul in heavy metal gym equipment.

Its designed to be sleek, not something thats going to end up collecting dust in your basement, Ashley Hennings, director of PR and influencer marketing at Tonal, told Insider at my live demonstration.

Unlike regular weights, the digital weights can adjust in real-time based on personalized workout goals.

For example, the program has something called burnout mode, which I found especially exciting. In a traditional burnout set (also known as a drop set), you select a challenging weight for a given exercise (like a bicep curl), lift that weight until you physically cant lift any more (known as muscle failure), slightly decrease the weight, and repeat until your muscles are totally tapped out. This helps build strength and mass.

Doing this at the gym requires some space and prior planning, since you have to estimate how much and what increments of weights youll need, and line them up in advance.

With Tonals burnout mode, though, you can program the digital weight to decrease automatically as you hit muscle failure, making for a much more streamlined burnout. This saves you the time of having to collect, and then wipe down and re-rack, multiple sets of weights.

The dynamic weight mode also offers some perks for advanced lifters. For instance, chains mode mimics the variable resistance of a chain attached to your barbell or weight, making it heavier on the way up (as the chains leave the ground) and lighter on the way down (as the chains return to the ground). Again, this is all digital, so you dont need chains carpeting your apartment.

The program also has some nifty safety features built in. The spotter mode feature recognizes when youre struggling (based on your range of motion) and gradually lowers the amount of weight to prevent injury, similar to a gym spotter making sure you dont drop a barbell on your face.

Plus, all the digital weight can be clicked off at the touch of a button, built into each of the handles, barbells, and grips that attach to the machine.

Every new Tonal user starts with a strength assessment, which is then used to create a customized profile from which you can track your workouts and see your progress. The system also uses this data to recommend the amount of weight and number of reps you should do in a given exercise, based on your previous workouts, making it accessible even to beginners.

You can also scroll through Tonals library of strength and aerobic fitness programs, many of which can be personalized. These also include video tutorials of various exercises to help less experienced athletes perfect their form.

Hennings said that Tonal is specifically designed to bring strength training to people who might otherwise be too intimidated to try lifting in a traditional gym.

This is all part of one of my favorite aspects of Tonal the system is designed to help people build strength, instead of focusing on weight-loss goals. Many other high-tech fitness systems (including Mirror and Peloton) are cardio-focused, and theres often an implicit or explicit suggestion that burning fat or shedding pounds is the goal.

Instead, Tonal tracks how much youre able to lift, which is a refreshing change, especially for women like me who go to the gym to get stronger, not smaller.

All in, Tonal costs about $4,000: $2,995 for the base price plus more for smart accessories and installation. So I dont expect it to replace most peoples monthly gym membership, mine included.

However, in a competitive market where everyone seems to be releasing a fitness app or trying to re-invent the wheel, it was exciting to see a tech company with a genuine gym innovation.

In my opinion, Tonal is an awesome home gym for folks who can afford it. Ill be looking forward to what the company comes up with next, especially if its something for the rest of us.

Read more:

We tracked over 1,000 peoples gym habits throughout 2019, and found they didnt ditch their resolutions by February

9 fitness trends that were all the rage in the 2010s, from CrossFit to exergaming

A $1,500 at-home fitness device beloved by Kate Hudson and Reese Witherspoon was the top trending exercise of 2019

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I tried a $3,000 high-tech home gym, and loved its sleek design and emphasis on strength over weight loss - Business Insider

Globally, fruits are one of the most important horticulture commodities due to its organoleptic and nutritional properties. In India, the diversity of agro climatic zones ensures availability of all varieties of fresh fruits and vegetables. The country ranks second in fruits production in the world after China. As per National Horticulture Database published by National Horticulture Board, India produced about 300 million metric tonnes of fruits and vegetables during 2016-17.

However, fruits are a highly perishable commodity as they contain 80-90% water by weight. The water quickly begins to evaporate, if fruits are left without cuticle, resulting in poor product shelf life. Absence of post-harvest treatment, non-availability of modern systems for storage, infestation of microorganism and pests, and lack of processing methods are resulting in post-harvest losses of about 25-30 per cent in fruit and vegetables. In addition, there is limited availability of cold chain facilities for storage and transportation leading to lower shelf life.

Scientists at Department of Biotechnologys Mohali-based National Agri-Food Biotechnology Institute have developed non-toxic and edible composite coatings based on wheat straw hemicellulosic polysaccharide (WP) and stearic acid derivatized oat bran polysaccharide (SAOP) that promise to overcome the problems.

They prepared emulsions of the composite and coated them on the surface of samples of apple, peach and banana. The coating helped to significantly reduce fruit weight loss and softening, and delay ripening. It also helped maintain sensory qualities compared to non-coated fruits. The formulation could extend the post-harvest quality of apple (Royal Delicious and Rich Red, Kinnaur) for up to or more than 30 days, peach up to 6-8 days and bananas up to 9 days without significant blackening under ambient storage. The coating technology is simple, and cost-effective. The edible coating material has potential as an alternative to commercially available animal based shellac coating in India, the scientists said.

An Indian patent has been filed on the formulation and a non-disclosure agreement (NDA) has been signed with R.G. Industries, New Delhi for commercialization of the technology.

(India Science Wire)

Twitter handle: @ndpsr

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Edible coating materials to improve shelf life of fruit crops - BusinessLine