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This One Exercise Melts Fat Faster Than Any Other, Says Science – Eat This, Not That

Posted: January 31, 2021 at 1:48 pm

The workout that melts fat fastest is also one of the quickest, typically taking less than 20 minutes from start to finish. Known as high-intensity interval training or HIIT, it requires you to move fast, very fast for a very short period of time. One researcher goes as far as calling it the "one-minute workout," because one version of this training method amounts to just 60 seconds of intensely strenuous exertion, 20-second bouts broken up by periods of rest, a sequence that's repeated multiple times.

You probably recognize this exercise techniqueas it has been written about here and elsewhere many times. But have you tried it? And, if so, have you done it correctly and endured this rigorous style of exercising long enough to notice results?

HIIT works. A number of studies have shown that short, vigorous workouts improve markers of good health like aerobic fitness, lower blood pressure, and more stable blood sugar. Workouts like HIIT can also burn more calories and reduce more visceral fat than typical endurance exercises like walking, running, and cycling at a moderate pace will when done for an hour or more.

How so? The science is complicated; strenuous exercise triggers certain changes on the molecular level that result in what's known as excess post-exercise oxygen consumption or EPOC. In other words, after exercise, you get a metabolic after-burn for about 24 hours where you burn more calories than normal.

More important than weight loss are the aerobic fitness benefits derived from quickie exercise sessions, say researchers. In a groundbreaking study from McMaster University in Canada published in PLOS One, researchers demonstrated that just one minute of intense effort in a 10-minute workout was enough to reap the rewards. In the study, 14 sedentary overweight men and women were asked to do a 10-minute workout on stationary bicycles, pedaling as hard and fast as they could for three 20-second intervals with 2-minute rest periods of slow pedaling in between. With a warmup and cool-down, the entire workout took just 10 minutes, 60 seconds of which was intense effort. After six weeks of these 10-minute workouts done three times a week, the cyclists significantly improved their aerobic capacity by 12% on average, lowered blood pressure numbers, and enhanced other markers of aerobic and muscular fitness. (Related: Simple Ways to Keep Your Heart Healthy.)

That's good news for people who blow off exercising because they say they don't have time to fit it into their busy days. This study proves it takes just one minute of hard work in 10 minutes of your precious workout time.

And it doesn't have to be performed on a stationary bike. Martin Gibala, PhD, professor of kinesiology at McMaster, and one of the lead researchers of the study, says almost any type of exercise can be performed as sprint-style intervals. He wrote a book The One-Minute Workout: Science Shows a Way to Get Fit That's Smarter, Faster, Shorter detailing several ways to incorporate HIIT training into your busy life.

One caveat: Sprint intervals are super, super difficult. People who don't get results most often aren't pushing themselves hard enough, trainers say. It's physically and psychologically challenging. You have to be OK with feeling discomfort.

"I tell people to imagine a bloodthirsty Rottweiler is chasing them and trying to take a bite out of their hamstring run like your life depends on it," says Denver-based personal trainer and fitness writer Eric C. Stevens. He makes another critical point: "To stay motivated at that level of exertion choose an exercise that you love doing. For me that's boxing and martial arts because of the skill set required and the sense of community." (Related: 10 Easy Ways to Burn Fat in 30 Minutes)

But it can be any activityrowing classes, cycling, brisk walking, even resistance trainingany activity where you can push yourself to near exhaustion for short bouts.

Stevens suggests two basic types of sprint intervals to try if you want to sample this super-fast way to get fit. But first, a critical step to avoid injury: Begin each HIIT workout with a total-body dynamic warm-up for three to five minutes, he says. Do arm circles while marching in place, jumping jacks, jump rope, inchworms, anything that gets all your limbs involved and raises your heart rate.

Use a stopwatch or clock with a second hand to keep time. After your warm-up, begin running, cycling, or rowing for 30 seconds at a light intensity. Next, do 20 seconds at a high intensity where you find it difficult to talk in complete sentences. Without resting, go right into a 10-second segment of maximum "rottweiler-in-pursuit" effort. You'll know you're pushing hard enough if you're too winded to speak. Repeat the 30-20-10 sequence four more times, followed by a three-minute cooldown of walking and stretching.

Always begin with a dynamic warmup for three to five minutes. Tabata training follows a 20-10 sequence. You begin with 20-seconds of high-intensity, all-out effort, followed by 10 seconds of rest (very slow pedaling or walking). Repeat the pattern seven more times for a total of four minutes. End with a cooldown.

"You can play with those interval times as long as you are getting the intensity," says Stevens. "Anerobic training takes a monstrous effort. It also feels terrible at times. But if you want the body of a dancer, a gymnast or sprinter, you have to train like one."

Since HIIT is so physically taxing, be sure that you are healthy enough before trying this exercise strategy. Visit your physician for a full physical exam.

Also, note that trainers like Stevens and researchers like Gibala stress that the most effective and efficient way to lose weight and maintain the weight loss is not through exercise but by reducing calories through a healthy diet. If sucking wind isn't for you, you may be interested in Lazy Ways to Lose Weight All Year Long.

For more healthy eating news, make sure to sign up for our newsletter!

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This One Exercise Melts Fat Faster Than Any Other, Says Science - Eat This, Not That

Testosterone Replacement Therapy Market Size Key Opportunity, Application And Forecast To 2027 The Courier – The Courier

Posted: January 31, 2021 at 1:47 pm

TheTestosterone Replacement Therapy Marketresearch report thoroughly explains each and every aspect related to the Global Testosterone Replacement Therapy Market, which facilitates the reports reader to study and evaluate the upcoming market trend and execute the analytical data to promote the business.

Testosterone Replacement Therapy Market Insight:

Testosterone replacement therapy market is expected to gain market growth in the forecast period of 2020 to 2027. Data Bridge Market Research analyses the market is growing at a healthy CAGR in the above-mentioned research forecast period. Rising prevalence of low testosterone level and related disorders worldwide and emerging markets are the factors responsible for the growth of this market.

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Table Of Contents: Testosterone Replacement Therapy Market

Part 01:Executive Summary

Part 02:Scope of the Report

Part 03:Research Methodology

Part 04:Market Landscape

Part 05:Pipeline Analysis

Part 06:Market Sizing

Part 07:Five Forces Analysis

Part 08:Market Segmentation

Part 09:Customer Landscape

Part 10:Regional Landscape

Part 11:Decision Framework

Part 12:Drivers and Challenges

Part 13:Market Trends

Part 14:Vendor Landscape

Part 15:Vendor Analysis

Part 16:Appendix

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The global Testosterone Replacement Therapy market report studies the contemporary market to forecast the growth prospects, challenges, opportunities, risks, threats, and the trends observed in the market that can either propel or curtail the growth rate of the industry. The market factors impacting the global sector also include provincial trade policies, international trade disputes, entry barriers, and other regulatory restrictions.

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Testosterone Replacement Therapy Market Size Key Opportunity, Application And Forecast To 2027 The Courier - The Courier

Testosterone Replacement Therapy Market Report | Size, Growth, Demand, Scope, Opportunities and Forecast 2020-2027 NeighborWebSJ – NeighborWebSJ

Posted: January 31, 2021 at 1:47 pm

Fort Collins, Colorado: The latest Reports Globe study titled Testosterone Replacement Therapy Market highlights important aspects of the Testosterone Replacement Therapy market. The report is intended to help readers accurately estimate the growth rate of the world market during the forecast period (2020-2027). Our market research team has meticulously assessed the Testosterone Replacement Therapy market dynamics, both quantitatively and qualitatively, taking into account a variety of factors including market penetration, product portfolios, user industries, results, pricing structure, and key drivers, restraints, opportunities, and challenges. affect market growth.

The latest market research largely segments the industry based on product types, application areas, end-use industries, key regions, and competitive environment. One of the central components of the report is a detailed explanation of the gross profit, the share of sales, the sales volume, the manufacturing costs, the individual growth rate, and the financial position of the main market participants. The scope of development of newcomers and established companies in the Testosterone Replacement Therapy market was also highlighted in the report.

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Competitive Field:

The Testosterone Replacement Therapy market is highly consolidated due to the presence of many companies operating in this sector. The report describes the current market position of these companies, their past performance, graphs of supply and demand, production and consumption patterns, distribution network, sales channels, and growth opportunities in the market. The main market candidates listed in the report are:

Market Segments by Major Manufacturers:

The most recent report includes extensive coverage of the significant impact of the COVID-19 pandemic on the Testosterone Replacement Therapy division. The coronavirus epidemic is having an enormous impact on the global economic landscape and thus on this special line of business. Therefore, the report offers the reader a clear concept of the current scenario of this line of business and estimates the aftermath of COVID-19.

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Testosterone Replacement Therapy Market Segmentation, By Type

Testosterone Replacement Therapy Market Segmentation, By Applications

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North America (USA, Canada)Latin America (Chile, Brazil, Argentina, rest of Latin America)Europe (UK, Italy, Germany, France, rest of the EU)Asia Pacific (India, Japan, China, South Korea, Australia, rest of APAC)Middle East and Africa (Saudi Arabia, United Arab Emirates, South Africa, rest of MEA)

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In continuation with this information, the sale worth is for varied sorts, applications, and regions also are enclosed. The marketplace for major regions is given. In addition, sort wise and application wise consumption figures also are given.

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Testosterone Replacement Therapy Market Report | Size, Growth, Demand, Scope, Opportunities and Forecast 2020-2027 NeighborWebSJ - NeighborWebSJ

Male menopause: symptoms, diagnosis and treatment – Netdoctor

Posted: January 31, 2021 at 1:47 pm

We've all heard of the menopause, when a woman's reproductive function starts to slow down but do men experience something similar? The term 'male menopause' refers to the physical and emotional changes that some men experience as they get older. It's a surprisingly controversial topic and experts are divided on the subject, with many disagreeing on what it is, how is should be defined, and if it even exists.

But while debate rages on about what to call this life stage, if you're a man in your late forties or older and you experience worrying symptoms including erectile dysfunction, a loss of sex drive, depression, or fatigue, it is worth getting checked out.

We spoke to nutritionist and male hormone expert Roberta Stringer, co-founder of testosterone health brand DNA, and Dr Luke Pratsides, lead GP at Numan, about the male menopause symptoms, causes and treatment options:

The male menopause, also known as andropause or colloquially as 'manopause' is a term used to describe a cluster of symptoms associated with an age-related decline in testosterone. Despite the name, male menopause differs substantially from female menopause.

Unlike the hormonal drop that occurs in women during this time, sex hormones tend to decrease more gradually in men. Not every man will experience andropause whereas all women experience menopause and men can still reproduce, while women can no longer become pregnant naturally.

'Male menopause is the gradual reduction of testosterone specifically related to ageing,' says Dr Pratsides. 'It is not strictly a menopause, which specifically refers to the cessation of menstruation in women where ovulation ends and hormone production plummets during a relatively short period of time instead, it happens over many years.'

Unlike the hormonal drop that occurs in women during this time, sex hormones tend to decrease more gradually in men.

Male menopause is not recognised as a medical condition. The term is often used alongside testosterone deficiency syndrome (TDS), which occurs when the testes produce few or no hormones. TDS is characterised by abnormally low testosterone levels (below 300 ng/dL) and has many different causes.

While it's true that many older men experience TDS approximately 40 per cent of men over the age of 45, according to a study published in the journal Frontiers in Endocrinology, and 50 per cent over the age of 80 abnormally low testosterone levels are not an inevitable result of ageing.

'Some men still maintain a normal level of testosterone throughout their lives, experience no symptoms and can father children well into their eighties,' says Dr Pratsides. TDS can affect men of any age, but when it occurs later in life, it's known as late-onset hypogonadism or androgen decline in the ageing male (ADAM).

The symptoms associated with male menopause are attributed to a gradual age-related decease in testosterone levels. 'Testosterone peaks at around the age of 20 in men,' says Stringer. 'Depending on health, diet and lifestyle factors, testosterone levels should remain consistent during men's twenties. They decline steadily from 30 at around one per cent a year.'

While declining T-levels are a given, 'the extent of decline and the age at which this happens varies even more so with today's lifestyle factors,' she says. The effects appear to be accelerating. One US study identified a 'substantial' drop in the general population since the 1980s, with testosterone levels declining by one per cent per year on average.

Stress, smoking, poor sleep, high body mass index, certain medications, lack of exercise and alcohol are all known to sap testosterone levels. Low T has also been linked to conditions like type 2 diabetes, high cholesterol, high blood pressure, metabolic syndrome and obesity, though it's unclear whether it's a cause or effect.

So, why is male menopause controversial? Some experts suggest that a gradual age-related drop in testosterone is not the primary cause of male menopause symptoms. They believe lifestyle and psychological factors play a far more prominent role. For example, feeling stressed because of problems at work could affect your libido and energy levels.

Male menopause is associated with physical, sexual, and psychological symptoms, that tend to emerge slowly and worsen as you grow older. 'Some men notice symptoms from their thirties, others in their sixties, and some particularly the older generation who were brought up at a time where male hormonal health was not discussed may not acknowledge any change at all,' says Stringer.

Common male menopause symptoms include:

If you're experiencing any of the symptoms associated with male menopause or have any concerns, make an appointment with your doctor.

When you visit your GP they will carry out a detailed check-up based on each of your specific symptoms and address them accordingly. They will also make sure to exclude other medical issues with relevant scans or tests as required.

Your doctor will carry out a detailed check-up based on each of your specific symptoms and address them accordingly.

Your doctor might ask about your personal life to determine whether other factors, such as stress or anxiety, play a part. They may also take a sample of your blood to test your testosterone levels. This will likely take place early or mid-morning, since your testosterone levels fluctuate though the day. A level of less than seven indicates low testosterone. Between seven and 14 is borderline, so further tests may be needed.

Some male menopause symptoms can be treated with hormone replacement therapy if your testosterone levels are found to be low. 'Testosterone replacement can be given in gels, patches, or injections,' says Dr Pratsides. 'It should always be guided by a suitably qualified clinician and obtained from a regulated provider.'

Testosterone treatment has various risks and side effects, including acne, worsened prostate cancer, enlarged breasts, disturbed breathing while sleeping (sleep apnea) and high red blood cell counts, which increases your risk of forming a blood clot. Men using testosterone therapy long-term appear to have a higher risk of heart disease.

If your symptoms are attributed to a combination of physical, lifestyle, and psychological factors, your doctor may adopt a more holistic approach. 'Symptoms of low testosterone due to advancing age can be treated individually,' says Dr Pratsides, 'for example, Viagra to help treat erectile dysfunction, or counselling to treat low mood.'

The simplest way to manage symptoms of male menopause is by making healthier lifestyle choices. Eating a well-balanced diet, making time for regular exercise, getting enough enough sleep, reducing your stress levels, and minimising alcohol and tobacco use are all recommended.

Hormone therapy isn't the only way to give your testosterone reserves a boost. Here are four evidence-based ways to increase your testosterone levels naturally:

Optimise your diet with a balance of carbs, healthy fats and protein. And don't forget the micronutrients. 'Nutrient deficiencies are increasingly common and can cause significant issues for maintaining positive testosterone levels,' says Stringer. B vitamins and zinc are particularly potent, improving sperm quality by 74 per cent in one study. 'Increasing your magnesium intake can raise testosterone levels within a month,' she adds.

Keep your favourite tipple for special occasions. 'Alcohol directly inhibits the production of testosterone in your testes,' says Stringer. 'It can also impact sleep as testosterone levels replenish overnight, this in turn can further impact levels.' Getting five hours a night can slash your T-levels by as much as 15 per cent, the University of Chicago Medical Centre found.

Maintain a healthy weight and pay attention to body fat levels, says Stringer. 'Obesity has a direct and negative impact on testosterone levels,' she explains. 'Fat cells metabolise testosterone to oestrogen, lowering testosterone levels. Also, obesity reduces levels of sex hormone binding globulin (SHBG), a protein that carries testosterone in the blood. Less SHBG means less testosterone.'

If you don't have a workout routine, now's the time to start. 'A 2004 study of older men found that regular physical activity increased testosterone and growth hormone (GH) levels as well as have a positive effect on brain function,' says Stringer. 'Resistance training has shown to be particularly beneficial for testosterone levels.'

Last updated: 28-01-2020

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Marius Pharmaceuticals Announces Co-CEOs Himanshu H. Shah and Shalin Shah to Drive Growth ahead of Anticipated FDA Action of its Lead Asset, KYZATREX…

Posted: January 31, 2021 at 1:47 pm

RALEIGH, N.C., Jan. 28, 2021 (GLOBE NEWSWIRE) -- Marius Pharmaceuticals, a specialty pharmaceutical company focusing on treating conditions that are primarily associated with testosterone deficiency, today announced that it has appointed Himanshu H. Shah and Shalin Shah as co-CEOs to drive the next phase of growth as the company looks to a potential launch of KYZATREX in Q4 2021 and further the development of Marius deep clinical pipeline.

Himanshu H. Shah brings over 30 years of experience across global capital markets and will continue his role as chairman of the board in addition to co-CEO. He has advised numerous public and private companies over the past decades to help them unlock substantial shareholder value and execute both innovative and pragmatic business strategies.

I am proud to continue serving Marius and work on developing the best treatment options for men with hypogonadism, a common but not widely discussed disease among patients and prescribers, said Himanshu H. Shah, chairman and co-CEO of Marius Pharmaceuticals. Misconceptions about hypogonadism are having a huge impact on the health of millions of men globally and costing the U.S. healthcare system alone billions of dollars annually. There is a huge opportunity for Marius to address these issues and drastically alter the testosterone therapy landscape.

Shalin Shah will also step into the role of co-CEO from chief financial officer and executive vice president of strategy for Marius. Shalin has been integral in driving overall strategy at Marius for the past four years and will oversee the growth of the team and execution of innovative models as it expands both clinically and commercially to become a leading pharmaceutical company.

I am excited for the opportunity to serve Marius in this new capacity, especially at a time when the world is seeing technology and healthcare intersect more than ever, truly helping patients, said Shalin Shah, co-CEO of Marius Pharmaceuticals. I am confident in Marius mission to better the lives of patients by ensuring adequate levels of testosterone and enhance patient care through disruptive technologies and personalization.

Om Dhingra, Ph.D., led the company from initial development of the lead compound through two successful Phase 3 clinical trials and will move into the role of vice chairman. He will help guide the companys clinical development plan and ensure KYZATREX and its differentiating safety and efficacy data is well known in the medical world.

It has been my great pleasure serving the company as CEO. I am very proud of the data we have generated, which we believe will position KYZATREX as the standard of care for patients suffering from hypogonadism globally, said Dr. Om Dhingra, vice chairman of Marius Pharmaceuticals.

If approved by the FDA, KYZATREX has the potential to become the new standard of care for treating patients with hypogonadism. Testosterone is a crucial hormone that is essential to sexual and reproductive health, but also has important functions in metabolic, inflammatory, cardiovascular and neurological health. In the U.S. there are at least six million symptomatic men suffering from hypogonadism, and over 100 million men globally. The resulting medical costs associated with men with untreated hypogonadism and related comorbidities are more than $25 billion in the U.S. alone. Current treatments on the market are dominated by therapies with unappealing administration methods, including auto-injections, in-office infusions and topical gels and creams that have a high transference risk. KYZATREX is an orally administered treatment that avoids the drawbacks that keep men from continuing treatment on available testosterone therapies.

About KYZATREX KYZATREX if approved, will represent a novel oral testosterone replacement therapy option for adult males indicated for conditions associated with a deficiency or absence of endogenous testosterone: primary hypogonadism (congenital or acquired) and hypogonadotropic hypogonadism (congenital or acquired).

The ReTUNE study was a multi-center, 12-month study across the U.S. that studied the safety and efficacy of KYZATREX in hypogonadal subjects (total testosterone 281 ng/dL). Efficacy was determined by number of subjects in the normal, eugonadal range after 90 days of treatment, including dose titrations, while safety was monitored for a further 9 months while on a steady dose. In addition to testosterone parameters, the study collected Patient Reported Outcomes (PROs), which showed statistically significant results both from baseline and against its comparator. A pivotal six-month Phase 3 study was conducted, in which subjects were monitored using ABPM, now considered the standard BP assessment by the FDA and clinical experts. An improved dose regimen was also used in the pivotal six-month Phase 3 study. The results of the Phase 3 studies will be published in leading medical journals and presented at national conferences in 2021.

The FDA has conditionally accepted KYZATREX as the trade name for this investigational drug. The safety and efficacy have not been fully evaluated by any regulatory authority.

About Marius PharmaceuticalsMarius is a specialty pharmaceutical company focusing on treating conditions that are primarily associated with hypogonadism, commonly referred to as testosterone deficiency. The companys mission is to improve the functional lives of patients and reduce the risks of the downstream effects of endocrine imbalance by ensuring appropriate level of testosterone. For more information, please visit http://www.mariuspharma.com.

Media Contact: Emily Brice919-610-3319ebrice@fwv-us.com

Photos accompanying this announcement are available at

https://www.globenewswire.com/NewsRoom/AttachmentNg/f825d70b-874a-4cef-9160-429f83bbfc66

https://www.globenewswire.com/NewsRoom/AttachmentNg/ba2569ca-0922-4b49-8d68-49424b5e44d4

Himanshu H. Shah

Co-CEO and Chairman of the Board, Marius Pharmaceuticals

Shalin Shah

Co-CEO, Marius Pharmaceuticals

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Marius Pharmaceuticals Announces Co-CEOs Himanshu H. Shah and Shalin Shah to Drive Growth ahead of Anticipated FDA Action of its Lead Asset, KYZATREX...

Male Hormone Replacement Therapy And The Side Effects – Nerd’s Magazine

Posted: January 31, 2021 at 1:47 pm

Testosterone replacement therapy is done to restore the testosterone levels in men. It is referred to ashormone replacementtherapy. Testosterone is a hormone in men that is produced in the testicles and helps to maintain sex drive, bone density, facial and body hair, sperm production, fat distribution, and red blood cells production. Testosterone levels are highest during adolescence and early stages of adulthood. The levels decline gradually as men age at around 30-40 years.

Testosterone in men may decline due to two reasons. First, it may be due to health conditions that have an effect on the testicles eg cancer, infection, and injury. The disease that results from low levels of testosterone is called hypogonadism. This condition prevents testosterone production by affecting the testicles and pituitary glands. Secondly, it may be as a result of natural decline as a man ages i.e. when men reach 30, they may start experiencing testosterone reduction. Low testosterone levels are considered normal but to some men, it may be extremely abnormal levels hence require replacement.

Decline testosterone levels can lead to symptoms such as reduced sexual desire with few erections that happen spontaneously, physical changes such as decreased muscle strength and mass, increased body fat, swollen and tender breasts, hair loss, fatigue, osteoporosis, emotional changes that lead to reduced motivation and self-esteem eg depression, and infertility. These symptoms can be a result of the side effects of the therapy, thyroid problems, diabetes, and obstructive sleep apnea. Hormone replacement therapy is administered to reverse the lowered testosterone levels in men. The therapy can be recommended to various people with the problem. Both healthy and aging men without hypogonadism diagnosis can be prescribed for testosterone replenishment on showing symptoms. Very high levels of testosterone on the other hand can also cause side effects such as the risk of stroke, infertility, enlarged breasts, and enlarged prostate.

There are several ways in which testosterone replacement can be administered. Testosterone can be taken in gels, intramuscular injections, patches, and topical creams. The method used for administration depends on ones lifestyle and the type of medical need. It can also be taken orally while being monitored to prevent it from being too high. Hormone replacement therapy is meant to induce and maintain secondary characteristics and to correct the symptoms and side effects arising due to low testosterone levels. Testosterone therapy can have some effects when used to prevent normal aging. It worsens sleep obstruction a disorder that causes abrupt stop and start of breathing, promotion of prostate cancer growth, stimulated overproduction of red blood cells increasing blood clotting risks, and reduction in sperm production or testicle shrinkage.

Hypogonadism can be diagnosed as primary or secondary hypogonadism. Abnormalities in testicular levels should be diagnosed, treated, and monitored. Hypogonadism causes testis failure hence reduced production of testosterone concentration and affect the normal number of spermatozoa. It can result from either defect that causes a change in the testis or the hypothalamus. Primary hypogonadism is a result of low T levels, raised gonadotropin levels, or impaired spermatogenesis. Causes of primary hypogonadism include trauma, HIV infection, cancer chemotherapy, myotonic dystrophy, testes exposure to radiation, and infectious orchitis. Secondary hypogonadism is due to low T levels, low or unsuitably normal gonadotropin levels, and spermatogenesis impairment. It is caused by severe obesity, androgenic anabolic steroid withdrawal, hypothalamic tumours, pituitary tumour, and surgery and deprivation therapy of androgen with gonadotropin.

Before testosterone therapy is administered, the clinicians discuss the potential risks and the need for monitoring. Urological evaluation is necessary for men with prostate nodule or induration. In older men, testosterone therapy has a life expectancy of up to 10 years and above. The therapy may lead to side effects and risks such as prostate cancer risk and require prostate monitoring. Some of the symptoms that are evident during T administration include.

Acne and oily skin

Reduced sperm production and fertility

Detection of subclinical cancer

Erythrocytosis

Metastatic prostate cancer growth

Male pattern balding

Breast cancer growth

Obstructive sleep apnea

Heart attack and heart disease

Before settling for testosterone therapy, it is important to take a few cations and think about all the aspects of the therapy. First, analyzing ones health history is key.it is advisable to first consider any other reasons that may be causing the symptoms that are similar to those of low testosterone levels. Sex dysfunctions can also be due to psychological or relationship issues. Cardiovascular disease can also be the reason behind erectile dysfunction. Several clinical measurements may be required to fully diagnose low testosterone levels. The tests are done on varied days and detailed interpretation is needed to establish the amounts of available testosterone. It is also necessary to have information on the possible risks and effects of the therapy and the side effects of the different methods used in administering testosterone.

Baseline evaluation before T administration is done helps to identify and exclude those prone to prostate cancer or who have a high risk of developing prostate cancer. Screening and monitoring in the case of cancer risk require patient and doctor agreement and patient awareness. Factors that should be considered during the baseline assessment are age, race, family history, and prostate examination results. Patient administered with T therapy requires frequent monitoring and assessment to establish whether the therapy is working and in case there are any adverse effects, and that they are responding to the treatment regimen. During the first 12 months of T treatment, it is advisable to get urological consultation to identify ant abnormalities.

Testosterone decline can be due to aging or medical conditions. The treatment and restoration of the levels of testosterone are referred to as testosterone replacement therapy. This therapy requires diagnosis, treatment, and constant monitoring. This is because the therapy treatment has different side effects and risks that vary from one patient to another. A qualified specialist team atLiv Naturalhelps by providing solutions to testosterone deficiency and solve any other health problems that result from low testosterone levels such as erectile dysfunction, low libido, and low muscle mass. Low T levels can only be determined by a diagnosis administered by clinicians i.e. testosterone level test.

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Things to know about Sildenafil and ED – ABCmoney.co.uk

Posted: January 31, 2021 at 1:47 pm

Erectile Dysfunction

It is a disorder in which the patient cannot get or keep an erection firm enough for sexual intercourse. If erectile dysfunction occurs from time to time, it is not a cause of concern. If it occurs regularly then it can cause stress, affect the self-confidence of an individual, and relationship problems to occur. It can also be a sign of some underlying health condition and can also contribute to heart disease.

Symptoms

The most obvious symptoms of erectile dysfunction include problems in getting and keeping an erection.

Causes

Keeping and getting an erection is a complex process that involves the brain, emotions, nerves, hormones and blood vessels also. Malfunctioning of any of these leads to erectile dysfunction. Stress and the mental health of an individual play an important role in getting and keeping an erection firm. Erectile dysfunction is also caused by certain physical issues, such as:

Treatment

Testosterone Replacement Therapy

Erectile dysfunction is not always caused due to a deficiency of testosterone. But once testosterone is identified for the condition, testosterone replacement therapy may improve the problem.

Erectile Dysfunction Surgery

Vascular reconstructive surgery improves the blood flow to the penis helping the person in getting and keeping an erection firm.

Erectile Dysfunction Vacuum Devices

It is an external pump with a band on it that a man with erectile dysfunction uses to get and maintain a firm erection.

Use of Sildenafil

A person with any type of sexual problem can try these tablets to treat erectile dysfunction after discussing with a health expert.

Mechanism of Action

Sildenafil with the brand name of Viagra helps in getting and keeping a firm erection by increasing the blood flow towards the penis. It is taken orally at least 30 minutes before sexual activity.

Side Effect:

People using Sildenafil have not shown any major side effects. It has more benefits as compared to the risk of side effects.

The common side effects include the likes of headache, stomach upset, blurred vision, dizziness. Stress-related to problematic sexual activity may put extra strain on the heart if the patient is already suffering from a heart problem.

Precaution:

Before using this medicine, the patient should tell the doctor if he has any heart problems. If the patient has survived a heart attack recently then he should avoid using sildenafil.

Patients with low blood pressure or with a history of painful erection should tell the doctor before using sildenafil.

Interaction:

Sildenafil is contraindicated with nitrates. It can cause a severe drop in blood pressure if used with nitrates. It should never be used with any medication indicated to treat heart attack or angina pain.

Storage:

The medication should be stored at room temperature away from moisture and light.

Prevention

Erectile dysfunction can be prevented by avoiding the use of alcohol. Reducing weight also reduces the risk of erectile dysfunction. Regular exercise is also recommended. Health experts have suggested walking, eating healthy and paying attention to vascular health as primary goals for treating erectile problems.

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Hormone Replacement Therapy Market Growth Analysis,Size,Insight,Share And Outlook By 2027 Pfizer, AbbVie, Novo Nordisk NeighborWebSJ – NeighborWebSJ

Posted: January 31, 2021 at 1:47 pm

Hormone replacement therapy refers to the treatment of the patients with hormone deficiency due to conditions such as dwarfism or women nearing menopause, which requires replacement of hormones in the body whose levels have become low. Market competition is intense. Eli Lilly, Pfizer, AbbVie, Novo Nordisk, etc. are the leaders of the industry, and they hold key technologies and patents, with high-end customers. Top 5 players combined 45.13% market share in all.

Market Analysis and Insights:

Global Hormone Replacement Therapy Market The global Hormone Replacement Therapy market size is projected to reach US$ 17720 million by 2026, from US$ 16210 million in 2019, at a CAGR of 1.5% during 2021-2026.

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Global Hormone Replacement Therapy Scope and Segment Hormone Replacement Therapy market is segmented by Type, and by Application. Players, stakeholders, and other participants in the global Hormone Replacement Therapy market will be able to gain the upper hand as they use the report as a powerful resource. The segmental analysis focuses on production capacity, revenue and forecast by Type and by Application for the period 2016-2027. The following manufacturers are covered in this report:, Eli Lilly, Pfizer, AbbVie, Novo Nordisk, Merck KGaA, Mylan, Bayer, Teva, Novartis, Abbott, Roche, Endo International, Ipsen, ANI Pharmaceuticals, TherapeuticsMD

Hormone Replacement Therapy Breakdown Data by Type

Estrogen Hormone, Growth Hormone, Thyroid Hormone, Testosterone Hormone, The proportion of estrogen hormone in 2018 is about 50%, and the proportion is in increasing trend from 2014 to 2018.

Hormone Replacement Therapy Breakdown Data by Application

Menopause, Hypothyroidism, Growth Hormone Deficiency, Male Hypogonadism, Other Diseases, The most proportion of hormone replacement therapy is used in menopause, and the proportion in 2018 is 46.2%. Regional and Country-level Analysis The Hormone Replacement Therapy market is analysed and market size information is provided by regions (countries). The key regions covered in the Hormone Replacement Therapy market report are North America, Europe, China, Japan and Middle East. It also covers key regions (countries), viz, the U.S., Canada, Germany, France, U.K., Italy, Russia, China, Japan, South Korea, India, Australia, Taiwan, Indonesia, Thailand, Malaysia, Philippines, Vietnam, Mexico, Brazil, Turkey, Saudi Arabia, U.A.E, etc. The report includes country-wise and region-wise market size for the period 2016-2027. It also includes market size and forecast by Type, and by Application segment in terms of production capacity, price and revenue for the period 2016-2027. Competitive Landscape and Hormone Replacement Therapy Market Share Analysis

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Table of Contents

1 Study Coverage 1.1 Hormone Replacement Therapy Product Introduction 1.2 Market by Type1.2.1 Global Hormone Replacement Therapy Market Size Growth Rate by Type1.4.2 Estrogen Hormone1.4.3 Growth Hormone1.2.4 Thyroid Hormone1.2.5 Testosterone Hormone 1.3 Market by Application1.3.1 Global Hormone Replacement Therapy Market Size Growth Rate by Application1.3.2 Menopause1.3.3 Hypothyroidism1.3.4 Growth Hormone Deficiency1.3.5 Male Hypogonadism1.3.6 Other Diseases 1.4 Study Objectives 1.5 Years Considered 2 Executive Summary 2.1 Global Hormone Replacement Therapy Sales Estimates and Forecasts 2016-2027 2.2 Global Hormone Replacement Therapy Revenue Estimates and Forecasts 2016-2027 2.3 Global Hormone Replacement Therapy Revenue by Region: 2016 VS 2021 VS 2027 2.4 Global Top Hormone Replacement Therapy Regions by Sales2.4.1 Global Top Hormone Replacement Therapy Regions by Sales (2016-2021)2.4.2 Global Top Hormone Replacement Therapy Regions by Sales (2022-2027) 2.5 Global Top Hormone Replacement Therapy Regions by Revenue2.5.1 Global Top Hormone Replacement Therapy Regions by Revenue (2016-2021)2.5.2 Global Top Hormone Replacement Therapy Regions by Revenue (2022-2027) 2.6 North America 2.7 Europe 2.8 Asia-Pacific 2.9 Latin America 2.10 Middle East & Africa 3 Competition by Manufacturers 3.1 Global Hormone Replacement Therapy Sales by Manufacturers3.1.1 Global Top Hormone Replacement Therapy Manufacturers by Sales (2016-2021)3.1.2 Global Top Hormone Replacement Therapy Manufacturers Market Share by Sales (2016-2021)3.1.3 Global Top 10 and Top 5 Companies by Hormone Replacement Therapy Sales in 2020 3.2 Global Hormone Replacement Therapy Revenue by Manufacturers3.2.1 Global Top Hormone Replacement Therapy Manufacturers by Revenue (2016-2021)3.2.2 Global Top Hormone Replacement Therapy Manufacturers Market Share by Revenue (2016-2021)3.2.3 Global Top 10 and Top 5 Companies by Hormone Replacement Therapy Revenue in 2020 3.3 Global Hormone Replacement Therapy Sales Price by Manufacturers 3.4 Analysis of Competitive Landscape3.4.1 Manufacturers Market Concentration Ratio (CR5 and HHI)3.4.2 Global Hormone Replacement Therapy Market Share by Company Type (Tier 1, Tier 2, and Tier 3)3.4.3 Global Hormone Replacement Therapy Manufacturers Geographical Distribution 3.5 Mergers & Acquisitions, Expansion Plans 4 Market Size by Type 4.1 Global Hormone Replacement Therapy Sales by Type4.1.1 Global Hormone Replacement Therapy Historical Sales by Type (2016-2021)4.1.2 Global Hormone Replacement Therapy Forecasted Sales by Type (2022-2027)4.1.3 Global Hormone Replacement Therapy Sales Market Share by Type (2016-2027) 4.2 Global Hormone Replacement Therapy Revenue by Type4.2.1 Global Hormone Replacement Therapy Historical Revenue by Type (2016-2021)4.2.2 Global Hormone Replacement Therapy Forecasted Revenue by Type (2022-2027)4.2.3 Global Hormone Replacement Therapy Revenue Market Share by Type (2016-2027) 4.3 Global Hormone Replacement Therapy Price by Type4.3.1 Global Hormone Replacement Therapy Price by Type (2016-2021)4.3.2 Global Hormone Replacement Therapy Price Forecast by Type (2022-2027) 5 Market Size by Application 5.1 Global Hormone Replacement Therapy Sales by Application5.1.1 Global Hormone Replacement Therapy Historical Sales by Application (2016-2021)5.1.2 Global Hormone Replacement Therapy Forecasted Sales by Application (2022-2027)5.1.3 Global Hormone Replacement Therapy Sales Market Share by Application (2016-2027) 5.2 Global Hormone Replacement Therapy Revenue by Application5.2.1 Global Hormone Replacement Therapy Historical Revenue by Application (2016-2021)5.2.2 Global Hormone Replacement Therapy Forecasted Revenue by Application (2022-2027)5.2.3 Global Hormone Replacement Therapy Revenue Market Share by Application (2016-2027) 5.3 Global Hormone Replacement Therapy Price by Application5.3.1 Global Hormone Replacement Therapy Price by Application (2016-2021)5.3.2 Global Hormone Replacement Therapy Price Forecast by Application (2022-2027) 6 North America 6.1 North America Hormone Replacement Therapy Market Size by Type6.1.1 North America Hormone Replacement Therapy Sales by Type (2016-2027)6.1.2 North America Hormone Replacement Therapy Revenue by Type (2016-2027) 6.2 North America Hormone Replacement Therapy Market Size by Application6.2.1 North America Hormone Replacement Therapy Sales by Application (2016-2027)6.2.2 North America Hormone Replacement Therapy Revenue by Application (2016-2027) 6.3 North America Hormone Replacement Therapy Market Size by Country6.3.1 North America Hormone Replacement Therapy Sales by Country (2016-2027)6.3.2 North America Hormone Replacement Therapy Revenue by Country (2016-2027)6.3.3 U.S.6.3.4 Canada 7 Europe 7.1 Europe Hormone Replacement Therapy Market Size by Type7.1.1 Europe Hormone Replacement Therapy Sales by Type (2017-2027)7.1.2 Europe Hormone Replacement Therapy Revenue by Type (2017-2027) 7.2 Europe Hormone Replacement Therapy Market Size by Application7.2.1 Europe Hormone Replacement Therapy Sales by Application (2017-2027)7.2.2 Europe Hormone Replacement Therapy Revenue by Application (2017-2027) 7.3 Europe Hormone Replacement Therapy Market Size by Country7.3.1 Europe Hormone Replacement Therapy Sales by Country (2017-2027)7.3.2 Europe Hormone Replacement Therapy Revenue by Country (2017-2027)7.3.3 Germany7.3.4 France7.3.5 U.K.7.3.6 Italy7.3.7 Russia 8 Asia Pacific 8.1 Asia Pacific Hormone Replacement Therapy Market Size by Type8.1.1 Asia Pacific Hormone Replacement Therapy Sales by Type (2018-2027)8.1.2 Asia Pacific Hormone Replacement Therapy Revenue by Type (2018-2027) 8.2 Asia Pacific Hormone Replacement Therapy Market Size by Application8.2.1 Asia Pacific Hormone Replacement Therapy Sales by Application (2018-2027)8.2.2 Asia Pacific Hormone Replacement Therapy Revenue by Application (2018-2027) 8.3 Asia Pacific Hormone Replacement Therapy Market Size by Region8.3.1 Asia Pacific Hormone Replacement Therapy Sales by Region (2018-2027)8.3.2 Asia Pacific Hormone Replacement Therapy Revenue by Region (2018-2027)8.3.3 China8.3.4 Japan8.3.5 South Korea8.3.6 India8.3.7 Australia8.3.8 Taiwan8.3.9 Indonesia8.3.10 Thailand8.3.11 Malaysia8.3.12 Philippines 9 Latin America 9.1 Latin America Hormone Replacement Therapy Market Size by Type9.1.1 Latin America Hormone Replacement Therapy Sales by Type (2019-2027)9.1.2 Latin America Hormone Replacement Therapy Revenue by Type (2019-2027) 9.2 Latin America Hormone Replacement Therapy Market Size by Application9.2.1 Latin America Hormone Replacement Therapy Sales by Application (2019-2027)9.2.2 Latin America Hormone Replacement Therapy Revenue by Application (2019-2027) 9.3 Latin America Hormone Replacement Therapy Market Size by Country9.3.1 Latin America Hormone Replacement Therapy Sales by Country (2019-2027)9.3.2 Latin America Hormone Replacement Therapy Revenue by Country (2019-2027)9.3.3 Mexico9.3.4 Brazil9.3.5 Argentina 6 Middle East and Africa 6.1 Middle East and Africa Hormone Replacement Therapy Market Size by Type6.1.1 Middle East and Africa Hormone Replacement Therapy Sales by Type (2016-2027)6.1.2 Middle East and Africa Hormone Replacement Therapy Revenue by Type (2016-2027) 6.2 Middle East and Africa Hormone Replacement Therapy Market Size by Application6.2.1 Middle East and Africa Hormone Replacement Therapy Sales by Application (2016-2027)6.2.2 Middle East and Africa Hormone Replacement Therapy Revenue by Application (2016-2027) 6.3 Middle East and Africa Hormone Replacement Therapy Market Size by Country6.3.1 Middle East and Africa Hormone Replacement Therapy Sales by Country (2016-2027)6.3.2 Middle East and Africa Hormone Replacement Therapy Revenue by Country (2016-2027)6.3.3 Turkey6.3.4 Saudi Arabia6.3.5 U.A.E 11 Company Profiles 11.1 Eli Lilly11.1.1 Eli Lilly Corporation Information11.1.2 Eli Lilly Overview11.1.3 Eli Lilly Hormone Replacement Therapy Sales, Price, Revenue and Gross Margin (2016-2021)11.1.4 Eli Lilly Hormone Replacement Therapy Product Description11.1.5 Eli Lilly Related Developments 11.2 Pfizer11.2.1 Pfizer Corporation Information11.2.2 Pfizer Overview11.2.3 Pfizer Hormone Replacement Therapy Sales, Price, Revenue and Gross Margin (2016-2021)11.2.4 Pfizer Hormone Replacement Therapy Product Description11.2.5 Pfizer Related Developments 11.3 AbbVie11.3.1 AbbVie Corporation Information11.3.2 AbbVie Overview11.3.3 AbbVie Hormone Replacement Therapy Sales, Price, Revenue and Gross Margin (2016-2021)11.3.4 AbbVie Hormone Replacement Therapy Product Description11.3.5 AbbVie Related Developments 11.4 Novo Nordisk11.4.1 Novo Nordisk Corporation Information11.4.2 Novo Nordisk Overview11.4.3 Novo Nordisk Hormone Replacement Therapy Sales, Price, Revenue and Gross Margin (2016-2021)11.4.4 Novo Nordisk Hormone Replacement Therapy Product Description11.4.5 Novo Nordisk Related Developments 11.5 Merck KGaA11.5.1 Merck KGaA Corporation Information11.5.2 Merck KGaA Overview11.5.3 Merck KGaA Hormone Replacement Therapy Sales, Price, Revenue and Gross Margin (2016-2021)11.5.4 Merck KGaA Hormone Replacement Therapy Product Description11.5.5 Merck KGaA Related Developments 11.6 Mylan11.6.1 Mylan Corporation Information11.6.2 Mylan Overview11.6.3 Mylan Hormone Replacement Therapy Sales, Price, Revenue and Gross Margin (2016-2021)11.6.4 Mylan Hormone Replacement Therapy Product Description11.6.5 Mylan Related Developments 11.7 Bayer11.7.1 Bayer Corporation Information11.7.2 Bayer Overview11.7.3 Bayer Hormone Replacement Therapy Sales, Price, Revenue and Gross Margin (2016-2021)11.7.4 Bayer Hormone Replacement Therapy Product Description11.7.5 Bayer Related Developments 11.8 Teva11.8.1 Teva Corporation Information11.8.2 Teva Overview11.8.3 Teva Hormone Replacement Therapy Sales, Price, Revenue and Gross Margin (2016-2021)11.8.4 Teva Hormone Replacement Therapy Product Description11.8.5 Teva Related Developments 11.9 Novartis11.9.1 Novartis Corporation Information11.9.2 Novartis Overview11.9.3 Novartis Hormone Replacement Therapy Sales, Price, Revenue and Gross Margin (2016-2021)11.9.4 Novartis Hormone Replacement Therapy Product Description11.9.5 Novartis Related Developments 11.10 Abbott11.10.1 Abbott Corporation Information11.10.2 Abbott Overview11.10.3 Abbott Hormone Replacement Therapy Sales, Price, Revenue and Gross Margin (2016-2021)11.10.4 Abbott Hormone Replacement Therapy Product Description11.10.5 Abbott Related Developments 11.1 Eli Lilly11.1.1 Eli Lilly Corporation Information11.1.2 Eli Lilly Overview11.1.3 Eli Lilly Hormone Replacement Therapy Sales, Price, Revenue and Gross Margin (2016-2021)11.1.4 Eli Lilly Hormone Replacement Therapy Product Description11.1.5 Eli Lilly Related Developments 11.12 Endo International11.12.1 Endo International Corporation Information11.12.2 Endo International Overview11.12.3 Endo International Hormone Replacement Therapy Sales, Price, Revenue and Gross Margin (2016-2021)11.12.4 Endo International Product Description11.12.5 Endo International Related Developments 11.13 Ipsen11.13.1 Ipsen Corporation Information11.13.2 Ipsen Overview11.13.3 Ipsen Hormone Replacement Therapy Sales, Price, Revenue and Gross Margin (2016-2021)11.13.4 Ipsen Product Description11.13.5 Ipsen Related Developments 11.14 ANI Pharmaceuticals11.14.1 ANI Pharmaceuticals Corporation Information11.14.2 ANI Pharmaceuticals Overview11.14.3 ANI Pharmaceuticals Hormone Replacement Therapy Sales, Price, Revenue and Gross Margin (2016-2021)11.14.4 ANI Pharmaceuticals Product Description11.14.5 ANI Pharmaceuticals Related Developments 11.15 TherapeuticsMD11.15.1 TherapeuticsMD Corporation Information11.15.2 TherapeuticsMD Overview11.15.3 TherapeuticsMD Hormone Replacement Therapy Sales, Price, Revenue and Gross Margin (2016-2021)11.15.4 TherapeuticsMD Product Description11.15.5 TherapeuticsMD Related Developments 12 Value Chain and Sales Channels Analysis 12.1 Hormone Replacement Therapy Value Chain Analysis 12.2 Hormone Replacement Therapy Key Raw Materials12.2.1 Key Raw Materials12.2.2 Raw Materials Key Suppliers 12.3 Hormone Replacement Therapy Production Mode & Process 12.4 Hormone Replacement Therapy Sales and Marketing12.4.1 Hormone Replacement Therapy Sales Channels12.4.2 Hormone Replacement Therapy Distributors 12.5 Hormone Replacement Therapy Customers 13 Market Drivers, Opportunities, Challenges and Risks Factors Analysis 13.1 Hormone Replacement Therapy Industry Trends 13.2 Hormone Replacement Therapy Market Drivers 13.3 Hormone Replacement Therapy Market Challenges 13.4 Hormone Replacement Therapy Market Restraints 14 Key Findings in The Global Hormone Replacement Therapy Study 15 Appendix 15.1 Research Methodology15.1.1 Methodology/Research Approach15.1.2 Data Source 15.2 Author Details 15.3 Disclaimer

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PARP Inhibitors Market is Driven by Increase in the Rates of Incidence KSU | The Sentinel Newspaper – KSU | The Sentinel Newspaper

Posted: January 31, 2021 at 1:47 pm

Global PARP Inhibitors Market: Introduction

A PARP (poly ADP-ribose polymerase) inhibitor is a substance that blocks PARP enzyme in the cell. DNA damage occurs during cancer. Blocking of PARP helps the cancer cells in repairing their damaged part of DNA.

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Global PARP Inhibitors Market: Competition Landscape

Key players operating in the global PARP inhibitors market are AstraZeneca, Tesaro, AbbVie Inc., Medivation, and Clovis Oncology. The global market is highly consolidated, with the presence of a small number of manufacturers. Increase in strategic collaborations and new product launches are expected to drive the global PARP inhibitors market during the forecast period.

AstraZeneca

AstraZeneca is a biopharmaceutical company engaged in the discovery, manufacture, distribution, and commercialization of biopharmaceutical products. The company is a leading player in the global pharmaceutical sector. It offers various services and products in therapeutic areas such as cardiovascular and metabolic diseases; oncology; and respiratory, inflammation, and autoimmunity (RIA). Additionally, the company provides products useful in the treatment of infections, neurologic disorders, and gastrointestinal diseases. With a high focus on research and development for certain specific aspects of neurodegenerative diseases, analgesia, and psychiatry, AstraZeneca continues to collaborate with other innovative partners across industry and academia. The areas of cognitive disorders, chronic pain, and other central nervous system disorders still experience significant unmet medical needs.

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AbbVie Inc.

AbbVie, Inc. develops and distributes pharmaceutical products worldwide. The company offers pharmaceutical products for use in testosterone replacement therapy and the treatment of hypothyroidism and autoimmune diseases. It distributes products directly to wholesalers, government agencies, distributors, health care facilities, and specialty pharmacies worldwide. HUMIRA, a biologic therapy for the treatment of autoimmune diseases, is the companys blockbuster drug. It accounted for around 63% share of the companys sales revenues in 2014. The company sells its products in more than 170 countries across the globe.

Global PARP Inhibitors Market: Dynamics

The global PARP inhibitors market is primarily driven by increase in the rates of incidence and prevalence of cancer. In addition, increase in the adoption of PARP inhibitor drugs, growth of geriatric population, and advancements in the global health care sector are expected to boost the global PARP inhibitors market in the next few years. Furthermore, the existing market players are deploying advanced techniques to come up with innovative methods for the development of technologically advanced treatments for cancer. This is likely to propel the demand for PARP inhibitors during the forecast period. However, frequent product recalls and stringent government regulations are expected to restrain the global market in the next few years.

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Increase in Incidence of Cancer Driving Global PARP Inhibitors Market

Cancer is the leading cause of death globally, after cardiovascular diseases. According to the World Health Organization (WHO), cancer accounts for 8.3 million deaths every year, with 70% new cancer cases expected to be reported in the next 20 years. Increase in the cancer-afflicted population is anticipated to be a key driver of the global PARP inhibitors market during the forecast period. According to a report by the Centers for Disease Control and Prevention (CDC) published in 2014, the number of cancer patients diagnosed in the U.S. reached approximately 21 million. The number is expected to reach 25.4 million by the end of 2024. Over 60% of the worlds new cancer cases occur in Asia, Africa, and South America. Nearly the same percentage of cancer deaths take place in these regions. Stomach, liver, lung, breast, and esophageal cancer are most prevalent worldwide.

Increase in Elderly Population Fueling Global PARP Inhibitors Market

Aging is associated with a large number of diseases and disorders. A majority of elderly people suffer from cancer. According to the Administration for Community Living, geriatric population (people aged 65 years or above) in the U.S. stood at 46.2 million in 2014. Thus, increase in elderly population is likely to drive the global PARP inhibitors market during the forecast period.

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Opportunities in Developing Regions

Developing regions such as Asia Pacific and Latin America are likely to be highly lucrative markets for PARP inhibitors in the near future. The market in these regions is projected to expand rapidly during the forecast period, owing to large population, increase in the number of hospitals, and rise in government investments in the advancement of health care facilities in these regions.

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PARP Inhibitors Market is Driven by Increase in the Rates of Incidence KSU | The Sentinel Newspaper - KSU | The Sentinel Newspaper

If you’re ready to drop the New Year’s weight loss resolution, this is for you – Wicked Local

Posted: January 30, 2021 at 12:53 am

Julia Taliesin|Wicked Local

By New Years Eve, the weight loss ads are hard to avoid. Companies calculate that January is when everyone resolves to finally shed the pounds, and, this year, it was all about losing the quarantine 15.

Well, quarantine isnt over, and January was full of tough pandemic news and political unrest. So, if that New Years resolution has fallen to the side, several local practitioners say it could be an opportunity to look at things differently.

Somerville dietitian and personal trainer Jessi Haggerty specializes in intuitive eating and size-affirming health care, concepts that have been around for a while but are now central to the Health at Every Size and fat positivity movements.

Intuitive eating is about how to help people honor what their body is asking for in terms of food, without goal of losing weight, she said. Its about honoring your bodys hunger and fullness, honoring cravings, and eating foods you enjoy and find pleasurable. Its what you want your life to look like we dont want our lives to feel restricted or miserable because were dieting all the time.

Haggerty acknowledged the pressure to lose weight is all around us, and noted that seeking weight loss is not necessarily a health-promoting effort.

Because we live in a culture that really prioritizes thinness and celebrates weight loss, most people I work with feel a pressure to lose weight, she said. The work Im doing with my clients is around body acceptance, and how to integrate behavior change that feels good for you, thats more focused on making yourself feel good versus lowering the number on the scale or trying to become smaller.

For people with chronic illnesses, or conditions that may in some way be helped by weight loss, Haggerty encourages self-compassion, education, and, again, listening to what your body needs when it comes to food and movement.

Unfortunately, a lot of patterns I see are what weve all internalized culturally: that our culture prioritizes a specific body type small and lean that we equate with health and which isnt necessarily true or helpful, she said. While I do talk to clients about protein and carbs, for the most part Im helping people develop a more helpful self-talk, to have curiosity and compassion around food.

Bethany Kregiel, a therapist at Somervilles Looking Glass Counseling, said she generally sees an increased focus on self-improvement this time of year. Kregiel specializes in eating disorders and OCD, and said she tends to work with clients to make sure any weight loss goals dont go too far.

I usually let my clients know up front that Im not a provider who promotes weight loss, and I work with them on understanding their current relationship with food and body image and how we can make that relationship better, she said. My approach is more about developing intuitive relationships with food and movement.

Kregiel, like Haggerty, guides her clients to listen to their bodys signals on when to move and what to eat.

Part of my approach with someone who has an unhealthy relationship with food and body image is understating their own bodys cues, accepting the cues, and accepting whatever their body is going to look like after following those internal cues, she said.

Kregiel also tries to get to the root of why weight loss is a goal, at all.

People get into this line of thinking, like things will be better for me if I lose 10 pounds, but thats not a solution if you have low self-esteem, she said. Thats going to be with you no matter what your weight is, so what is the root of desire to make this change, and is there another way to tackle this that is not the Band-Aid of weight loss?

CrossFit Somerville owner J.T. Scott, who also serves as Ward 2 City Councilor, has worked to create a fitness community that focuses on agency and strengthening peoples ability to create change in them and in the world.

We believe people who are stronger and more capable are better positioned to change the world, and we believe in the desire of most everyone to change the world for the better, he said. Its that agency that is the foundation of creating all sorts of positive social and structural change in the world.

Unlike other fitness venues, weight loss is not a primary focus in Scotts gym. When clients come in with specific goals like meeting a height/weight ration to join the Marines he works with them one-on-one, but general classes prioritize body safety while encouraging members to push their limits.

Its in how we model our behavior: none of our coaches are walking around talking about oh, Im so fat and slow, its I am how I am, he said. I think fitness and weight loss culture creates larger culture of shame and valuing people based on appearance, when the range of human normal is very wide.

Haggerty believes theres a lot to be gained when we stop fixating on weight loss.

Its so nice not to be obsessing over everything Im eating or not eating, it allows us to have deeper connections with people discover what youre actually passionate about, she said. It sometimes results in a career change, and people realize they have space for hobbies and other things they enjoy.

Kregiel agreed there is so much lost when weight loss is the only goal.

First and foremost are social interactions such a big part of the way we socialize is around food, and youre going to be taken out of the moment when youre obsessing over food eating when youre with other people, she said. It makes me sad when people limit themselves from having something they really want. Theres a lot of freedom that comes with letting go of a diet, eating what you want to eat, and not feeling bad about it.

Instead of diet and weight loss goals, resolve to focus on things you love.

Im not setting these weird diet goals anymore, Im focused on other things,said Haggerty. I have a new creative writing practice, and Im starting a book club. When I think about intentions or resolutions that have enhanced my life, any time Ive ever engaged in restrictive diet, Ive never felt it was really life enhancing. I encourage people to think about goals you can still have goals around food and body image but prioritize what is going to feel fulfilling and life enhancing.

Read more from the original source:
If you're ready to drop the New Year's weight loss resolution, this is for you - Wicked Local


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