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30 years of supporting nutrition research – Penn State News

Posted: October 28, 2020 at 3:55 am

A persons diet affects almost every aspect of their health, from heart disease to mood regulation. For 30 years, Penn States Diet Assessment Center has collected and analyzed high-quality dietary data in order to help researchers clearly understand what, how, and when people are eating.

Measuring what people eat in the course of their normal lives is notoriously difficult. When asked, people often fail to report their intake accurately. Remembering every food and beverage consumed and estimating the amount of food consumed can be a daunting task for many.

Despite the challenges, understanding diet is critical. The Diet Assessment Center, housed within Penn States Department of Nutritional Sciences, has been providing expert data collection to address this need for decades. It has developed a reputation as one of the best resources for researchers who need to plan, collect data, or analyze data in the field of nutrition.

The Diet Assessment Center provides data collection and research expertise that is central to understanding nutrient intake and to analyzing the behavioral aspects of what, when, and how people eat. A lot of training and experience is required to be able to query adults and children about their diet and get reliable information from them. Diet assessment is a cornerstone of nutrition research and many other types of studies, for example of the microbiome or metabolic diseases. It is well established that diet underlies about half of the risk of many chronic diseases, so learning what people -- individuals and groups -- actually consume is essential to public health science. said A. Catharine Ross, professor of nutrition and physiology, and Dorothy Foehr Huck Chair in the Nutritional Sciences department.

Researchers in the Diet Assessment Center collaborate with nutrition researchers, government agencies, and private companies to collect and analyze data. The researchers in the center have worked on dozens of studies, large and small.

Collaborating for a healthier population

The Geisinger Rural Aging Study has been one of the hallmark studies of the Diet Assessment Center, said Diane Mitchell, associate research professor of nutritional sciences and director of the Diet Assessment Center. The original principal investigator was Gordon Jensen, former head of Penn States Nutritional Sciences department. Currently, Christopher Still at Geisinger is the principal investigator. Under their leadership, the study has investigated a broad array of topics that can improve the health of rural Americans.

In many ways, the Geisinger Rural Aging Study has served as the bread and butter of the center, allowing us to continually improve our methods, Mitchell continued. Funded through a cooperative agreement with the United States Department of Agriculture and Geisinger Health System, it has provided resources to develop and test dietary methods to assess nutrition risk and diet quality.

According to Mitchell, the study has collected and analyzed dietary and other health-related data for more than 21 years on over 20,000 older adults in Central Pennsylvania. It is the longest running study conducted in the Diet Assessment Center. The study has helped researchers better understand how diet affects health as people age and has led to dozens of scientific publications.

Recently, the investigators uncovered new insights about the connection between diet quality and mortality. In the next several years, the project will focus on other neurological outcomes such as Parkinsons disease and dementia. This work is being guided by Xiang Gao, professor of nutritional sciences.

Data collection, instrument validation, and more

Over the life of the Diet Assessment Center, researchers have collected more than 75,000 dietary recalls. During a dietary recall, researchers call study participants at random times on select days over the course of the study, which prevents participants from consciously or subconsciously editing their responses in advance. The participants explain what they ate during the 24 hours before they received the call. For most dietary recall studies, the center uses the Nutrition Data System for Research (NDSR), a software program developed by the University of Minnesota. The NDSR database allows for automatic calculation of over 150 nutrients and food components participants are consuming such as fat, protein, calories, vitamins and minerals.

Though the center is best known for collecting dietary recalls, the Diet Assessment Center also provides research support for studies involving the collection and analysis of food records; the development, validation, and collection of food frequency questionnaires; and the collection of a variety of other types of telephone or self-administered questionnaires including physical activity, functional status, and health history.

We recently wrapped up a collaboration with the American Cancer Society on the modification and validation of a food frequency questionnaire, Mitchell explained. We used detailed food data to modify an existing food frequency questionnaire to reflect the diets of the Cancer Prevention Study-3 participants. The American Cancer Society uses dietary data collected via food frequency questionnaires to study the effect of diet on the development of cancer in over 300,000 Americans, so it is important that these data represent the population being studied.

Promoting undergraduate research

One unique aspect of the Diet Assessment Center is that they train undergraduate students to collect data. This gives students a unique opportunity to be involved in research collecting high-quality dietary data for ground breaking nutritional studies. It prepares the students for graduate school and employment by grounding them in rigorous research protocols while enhancing communication skills. For the investigators who collaborate with the Diet Assessment Center, employing a highly trained student staff results in a more efficient and cost-effective approach to data collection.

Looking forward

Thirty years into its existence, the Diet Assessment Center shows no signs of slowing down.

Im very excited about the future, Mitchell said. Advances in nutritional sciences require that we continue to develop and refine approaches to better capture diet, and this is a top priority for government-sponsored nutrition research. This aligns very well with the expertise of the Diet Assessment Center.

Researchers who are interested in collaborating with the Diet Assessment Center are encouraged to visit the centers website or email Diane Mitchell at dcm1@psu.edu.

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30 years of supporting nutrition research - Penn State News

The Effects of Sugar on the Brain How Sugar Affects the Brain – GoodHousekeeping.com

Posted: October 28, 2020 at 3:55 am

Aleksandra MedvedevaGetty Images

Sugar rush. Sugar high. Sugar buzz. Sugar slump.

We've all heard these phrases that describe what our brains feel like when we've had too much of a sweet treat. But heres the thing about sugar and your brain: Your noggin needs it because sugar is its main fuel. Our brains run on glucoseit fuels our cells, including our brain cells. Were evolutionarily programmed to like sweets since theyre a great energy source. And when glucose levels are low in the blood (say, if you have hypoglycemia, or sometimes if it's just been a while since you've had something to eat), brain fog sets in, you fumble for words, you forget where you put down your phone, you look for a place to curl up for a quick nap.

When theres too much sugar in the system, however, that can set off some really bad stuff in your body and your brain.

When sugar hits our tongue, it activates certain taste buds that send a signal up to the brain, including the cerebral cortex, says Nicole Avena, Ph.D., assistant professor of neuroscience at Mount Sinai School of Medicine, who wrote a book about sugar addiction. The signal activates the brains reward system; dopamine (a feel-good brain chemical) is released and the behavior is reinforced, which makes us want to repeat it (mmmm, thats nice, give me more!).

Sugar is rare among dopamine-producing foods, Avena points out. Most of the time when we eat something new and tasty, dopamine is released the first time we taste it, she explains. This is an evolutionary advantage to help us to pay attention to new and different tastes, in case they make us sick. If we eat something new and don't get sick, typically the dopamine response then goes away the next timeso basically we only release dopamine in response to eating new foods. However, sugar is different. Its more like what happens with a drug of abuse, where dopamine is released every single time its consumed. Eating lots of sugar will continue to feel rewarding because the dopamine level doesnt balance out, which it does when eating healthier foods. So sugar does act a bit like a drug in our system which is why people get hooked on sugary foods.

We used to have to forage for sweet foodsbut no more, of course. Our world is filled with sugary foods and not just the obvious donuts and super-sweetened, super-large latte drinks. A host of surprising foods from ketchup to salad dressing to marinara sauce have sugar added to them. But our brains still function like sugar is a rarity.

When you repeatedly activate that reward system, your brain adapts and actually rewires itself, and you crave more and more. And research on rats turned up this finding: When they were fed high-sugar diets, the rats brains released less of a certain chemical that helps bodies put on the brakes, so they were less able to stop eating it.

Those sugar-saturated rats also werent as good at certain memory tasks, which showed that certain brain functions in the prefrontal area and hippocampus (an important area for memory formation and retention) were impaired. Other rat studies showed that a high sugar diet increased inflammation in this area, which also affected short term memory.

You may not be aware that theres a strong connection between our gut and our brainand sugar comes into play here as well. When that sugary thing youve eaten hits your gut, Avena says, it activates sugar receptors there too, which signal the brain to release insulin to deal with the extra sugar youve eaten. To explain further: Excess sugar drives the pancreas to produce extra insulin, a hormone involved in blood sugar regulation. The insulin signals fat cells to store excessive amounts of glucose, fatty acids, and other calorie-rich substances. As a result, too few calories remain in the bloodstream, so the brain thinks its now low on fuel (since it has those very high energy needs). So your hunger level rises quickly. And sugar is appealing then because it provides quick energy. Thus, the cycle begins again. And thus, cravings for more and more brownies or ice cream or candy.

Sugar Shock: The Hidden Sugar in Your Food and 100+ Smart Swaps to Cut Back

Want to get your brain in line with a healthier sugar level? Your brain can readapt when you cut back on sugar, and you wont crave it as much, says Avena. However, it can take awhile, even months, for this to happen, depending on the severity of dependence on sugar that one has.

To find out more about how to start cutting back on sugar and shake off a sugar dependence, try a 7-day detox plan. When you can successfully cut back, there's a payoff, besides a much healthier body: Just a small taste of, say, that delicious chocolate brownie will be enough of a sweet treat to satisfy you.

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The Effects of Sugar on the Brain How Sugar Affects the Brain - GoodHousekeeping.com

11 Ways to Stay Healthy This Season – Adventist Review

Posted: October 28, 2020 at 3:55 am

October 27, 2020

By: AdventHealth, and Adventist Review

The holidays have a way of throwing off our routineseven during a typical year. With added levels ofstress and uncertainty due to the COVID-19 pandemic, it can be even more challenging than usual to focus on nutritious foods, exercise, and other components of a healthy lifestyle.

First,giveyourself some grace.Guiltoveran extra dessert or a missed workoutis unnecessary and unhelpful. Criticizing yourself, or your family, for imperfection might lead to even more tension and anxiety.

That said, taking care of your health can help you cope better with lifes ups and downs. Plus, poor nutrition and a lack of physical activity can increase your risk of other health problems in the long run, from obesity to heart disease to certain cancers. Some of these conditions also put youatan increased riskfor complications from COVID-19, according tothe Centers for Disease Control and Prevention (CDC).

You might have to be a little more creative to ease stress and incorporate movement this fall and winter. But if 2020 has brought anything, itsa mindsetofflexibility. Hereare some strategies totrythis holiday season.

Focus on the Positives

Instead of dwelling on what will happen if you eat poorly and stay sedentary, consider the perks of eating better and getting moving.

If you eat a healthy diet, youll live longer and reduce your risk for chronic health conditionsor manage the ones you already have. The perks of exercise begin nearly immediately after a workout and include reduced anxiety and depression and better sleep.

Dont Deny YourselfFamilyFavorites

Many traditional holiday foods wouldnt necessarily appear on a list of the healthiest dishes. Theyre often high in calories, saturated fat, or added sugars.

Thats OKyou can still enjoy them. Just choose one or two of your favorites, and eat them in small portions. Balance them out with vegetables or other nutrient-rich ingredients.

You can also try modifying recipes for instance, grilling or baking your proteins instead of frying them, or swapping out heavy cream for lighter versions. Or, try an entirely new dish. You might find a new holiday favorite.

Sneak in Extra Vegetables

Good nutrition isnt all about what you dont eat, anywayits often just as important to add in more nourishing nutrients. After all, fewer than one in 10 children and adults eat enough vegetables, the CDC reports.

Eating more plants can ensure you get enoughessentialvitamins and minerals. Try slicing up raw veggies and keeping thembagged in the fridgeas snackstheyre far easier to grab when theyre already bite-sized. Add beans or peas to soups andsalads.

Turn Your Plate into a Party

Another simple, festivetrick to up your fruit and veggie intake? Eat as much of the rainbow as you can. Orange citrus fruits, bright-red tomatoes, purple eggplants and berries, and dark, leafy greens all contain different vitamins and minerals.

At each meal, see if you canintroduceone more hue to your main or side dish.Fresh herbs add a dash of green to brothy soups; orange andredpeppers can brighten up a dull egg dish; berries can provide a pop of blue andpurpleto yogurt.

Fill Up on Fruits

Some call them natures candy for a good reason. Fruits make excellent desserts, and theyre also a key part of a healthy diet, filled with disease-fighting nutrients. Plus, theyre lower in fat and added sugars than other sweet options.

Cut up melon, papaya, and mango, and top with fruit-flavored yogurt for a tropical treat. Sample a more exotic variety, like pomegranate orstarfruit. And when it comes to pies, pumpkin beats pecanits still sweet, butit has aboutone-third of the sugar and calories.

Start the Day Right

Skipping breakfast will likely only make you hungrier later in the day and more prone to overeating unhealthy foods. Plus, your morning meal represents a prime opportunity to boost your diet with produce. Only 10 percentof foods typically consumed at breakfast are fruits or vegetables,according to the CDC.

Upgrade your day early with a veggie-rich omelet swap out one egg or half the cheese and stir in spinach, onions, and mushrooms. Slice bananas or strawberries into cereal. Or, try a special holiday-themed bowl stir dried cranberries or cooked canned pumpkin, and pie spices like nutmeg and cinnamon into oatmeal.

At Night, Sleep Tight

Finishing out the evening with a good nights rest can also go a long way in keeping you on track. When youre sleep-deprived, youre more likely to eat mindlesslyand crave high-fat, high-sugarfoods.

Aim for seven to eight hours a night. Try to go to bed and get upat thesame time every day. Keep your bedroom quiet, relaxing, darkand free of lighted screens, which disrupt your slumber.

An evening routine, such as listening to calming seasonal tunes, can help you wind down. And try not to eat a large, heavy meal too close to bedtime.

Take a Walk

Walking is always an excellent way to fit more activity into your day. Start your mornings with a walk around the block or up and down the stairs. If you have holiday errands, park farther away from your destination so you can get in a few more steps.

When youre doing sedentary activities whether working, writing holiday cards, or watching seasonal movies take periodic breaks for a stroll in your neighborhood. Try to make your motion add up to 150 minutes per week that's at least 20 minutes a day, or 30 minutes five days aweek.

Try Some Music

Weather outside too frightful? Get creative with indooractivities.Turn on your favorite holiday tunes with their spritely rhythmsits a sure-fire way to get the whole family moving.

Some gyms or fitness instructors offer holiday exercise challenges, such as doing a certain number of squats or push-ups each day. Search YouTube for options, or start your own. You can award prizes to your family or recruit faraway friends as a way to stay connected.

Make Time for You

Clearing space in your day for activities you enjoy isnt selfish or a luxury its a critical way of managing stress and your mental health. Whether it's a nap, a hot bath, an engaging book, or relaxing music, carving out a few minutes for you will restore your energy so you can handle the next challenge.

Or, simply unwind and take a few deep breaths. Remind yourself that your emotions arevalid andrealbut even strong ones will fade.

Create New Holiday Memories

Many of our normal holiday activities will look different this year. Plan new activities focused on connection, movement, and fun and not just around sitting and eating.

Sign up for a turkey trot family run or holiday dash race, either in real life or virtually. Walk-and-talk dates with your family and friends, ice skating, or taking a bike ride past holiday lights when the weather is safe can add a festive mood to your day, all while boosting your health and well-being. There's no time like the present to start a new tradition.

The original entry was posted by AdventHealth.

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11 Ways to Stay Healthy This Season - Adventist Review

I got a whole new mindset: the health secrets of people who got much fitter in lockdown – The Guardian

Posted: October 28, 2020 at 3:55 am

Before Covid-19, an ordinary evening for Tim Ludford, a charity worker, looked something like this: after-work drinks with colleagues; an Uber home; a takeaway. Not healthy takeaways, either, says Ludford, 37, from London. He would polish off a curry for two people before nailing a bag of Maltesers or a packet of biscuits.

Ludfords relationship with food began to deteriorate after the death from cancer of his father in 2013. I was unhappy, first of all, and I was bingeing on food and alcohol as a coping mechanism, he says. A lot of it was related to my dad, but I was also stuck in a rut and food was an easy way to make myself feel good. By the time lockdown was introduced, he was severely obese, with a BMI of 40. (A healthy BMI is between 18.5 and 24.9, according to the NHS.) Sometimes Id do crazy things, he says. If I was on the way to meet someone for dinner, Id go to KFC on the way. And then Id eat dinner as well.

Then Covid-19 hit. Ludford was too scared of the transmission risk to order a takeaway. The pubs were not open. I started cooking at home, he says. Soups, salads healthy stuff. He was furloughed and began to struggle with anxiety, in part related to the pandemic, but also related to his health. His dad had had a heart attack before he died, and Ludford began to panic that he would, too. The sudden death of a friend from a heart condition, in April, sent him to a dark place. It was like all this anxiety I had been pushing away, about my health and my weight, suddenly opened a crack, he says. And, because I was on furlough, I had time to focus on it. Everything fell apart. My brain decided that this was my comeuppance: I was going to have a heart attack, as payback for the irresponsible lifestyle Id been leading.

Ludford spoke to a GP about his anxiety, who recommended exercise and referred him for counselling. So, he started walking: 2km became 5km became 10km, he says. And he exercised to videos he found on YouTube. At first, he could not manage a single burpee, but after a few months, he was flinging himself on and off the floor with ease. The exercise was the only thing that really helped me to get a handle on my anxiety, he says. Exercise kept the wheels on the bus. Seven months on, Ludford has lost 34kg (5st 5lb) and is no longer severely obese. But the weight loss is secondary to his mental wellbeing he feels like himself again. Everything came together at the same time, he says. Lockdown was the trigger.

While lockdown was a period of indulgence for many of us who can blame anyone for looking at a world in freefall, with political leaders squabbling like children, and reaching for the biscuit tin? the enforced stillness of 2020 gave some people the time and headspace to embrace a more active lifestyle. Freed from the shackles of the commute and the lure of late-night pub sessions, an overhaul was in reach. Fiona Gillison, a chartered psychologist and behaviour-change expert at the University of Bath, says: The pandemic reduced the barriers that many people have to leading healthier lifestyles by giving them more time at home or dedicated time to exercise.

Gillison believes that the fact the government made exercise one of the only exemptions from the Covid-19 restrictions during lockdown helped reinforce the notion that it was a priority, even during a pandemic. We were allowed out for one hour a day for exercise, and that was one of the only things we were allowed to do, she says. Thats quite strong public health messaging. In effect, the government was saying: Look, this is worth leaving the house for; this is worth the risk. Exercise also became social: families traipsing out for walks together, friends meeting for a hike.

Plus, during lockdown, there was not much else to do. Sue Wild, 67, a retired midwife from Birmingham, says: I thought to myself: what else am I doing? I might as well try to get fit. Wild has never been an exercise fan: she completed the NHSs Couch to 5K app a few years ago, for a bet, but it did not stick. This summer, for want of anything to do, she downloaded it again and started running once more. It was strange, she says. I never enjoyed it before. But I think, because Im not going out as much, its nice to have a bit of time to look around and feel like things are normal.

Initially, I was only doing this because I had nothing to do. But it went on for so long that it became a habit

The pandemic is more dangerous for older people, obese people and those with underlying health conditions. I know that Covid-19 isnt going anywhere, says Wild, who is just outside the age bracket (70-plus) in which she would be most at risk from the virus. So, I have to be the fittest that I can be. I just feel like, if I did get it, Id want to give myself the best shot possible for a good recovery.

She is not alone. A recent study from University College London, which tracked 5,395 people via a smartphone app, found that over-65s were among the most active of all the groups surveyed throughout lockdown and increased their physical activity levels the most once the lockdown restrictions were eased. It was also the only age group to become more active during the pandemic than beforehand.

In July, prompted largely by the prime ministers spell in intensive care Johnson believes he was hospitalised with the virus due to his weight the government announced an anti-obesity strategy. (Critics pointed out that the measures did little to address the structural reasons for obesity, such as inequality.) The messaging appears to be working, at least for Ludford. I am very aware of how obesity is a risk factor, he says. That was a big motivation to get down to a healthy BMI.

For Shae Eccleston, 42, a consultant from Dunstable in Bedfordshire, it was a way to sort out her chronic insomnia, not just for her own health, but so that she could be there for her family. Five members of her family fell ill with Covid-19 at the same time her mum, her grandfather, her grandmother and two aunts. I was doing a lot of supermarket shops and making sure they were taken care of, she says. I just knew that I could not afford to get sick. I had to be resting. I couldnt afford to be knocked down as well.

Before the pandemic, she averaged two to four hours sleep a night. Ive always been bad at sleeping. My mum says that, even when I was a baby, I was always awake. It was a good night, if I fell asleep before the sun came up, she says. But her familys brush with Covid-19 thankfully, everyone pulled through was a wakeup call. Now, she puts her phone on Do Not Disturb, listens to ASMR videos, and has made her bedroom a screen-free zone. (Previously, she would often work on her laptop in bed.) Ive been getting a good six hours sleep a night, she says. To other people, thats nothing. But its huge for me.

It is easier to form better habits if your lifestyle has been upended. Covid disrupted all of our routines, says Gillison. When you have to create a new routine, your old habits are disrupted and youre more in charge of how you shape your own life. That will play a role in why people may be embracing healthier behaviours. Covid-19 acted as a jolt for many. Ludford had tried dry January and health kicks before, but nothing stuck. Suddenly, going on as normal wasnt an option, he says. Before, Id been able to live a certain lifestyle. And then this big interruption came along. Eccleston, too, thinks she would have continued in her old ways late-night phone calls to friends, working in her bedroom until the early hours were it not for the shock of lockdown. Suddenly, everything changed and I got a new mindset, she says.

When so much is out of your hands, exercise is something you can control. Theres something about the sense of autonomy you get from exercise, says Gillison. Youre doing it for your own reasons, rather than because someone told you to. With Ludford on furlough, exercise gave him a sense of drive and purpose. Ive felt so stuck this year, he says. You cant plan ahead in your life the way you want to or are used to. Exercise has enabled me to focus on a series of goals that I can achieve.

For many people, upping their exercise helped them deal with the stress and anxiety of living through a pandemic. I know my own mental health quite well, says Tom Firth, 33, a teacher from Yorkshire. If I dont do something productive with my day, I start to dislike myself. Before lockdown, he often worked 12-hour shifts, treating the summer holidays as a period for recharging. Id think that I should be healthier, but I never had the time, so I just gradually ignored it and got more and more unfit, he says.

In Firths defence, British people work some of the longest hours in Europe an average of 42 hours a week in 2018, two hours more than the EU average and the equivalent of an extra two and a half weeks a year. Studies have shown that working longer hours is bad for your mental and physical health, contributing to physical inactivity and an increased risk of depression. In the early weeks of Covid-19, Firth took advantage of his downtime to watch appalling amounts of TV: The entirety of Tiger King in an afternoon, that sort of thing.

But he could feel his mental health deteriorating, so he got on his exercise bike. Firth set himself the goal of cycling 1,000 miles a month, tracking his miles on a spreadsheet. During the Tour de France, he cycled along; now, he watches Parks and Recreation on the bike. Firth credits his exercise regimen with giving him the resilience to get through the pandemic. He has also lost 20kg. Exercising for an hour a day has done wonders for my mental health, he says. It releases all these lovely chemicals. Its literally addictive.

Will these habits stick when people return to their old lifestyles? Firth thinks so: even though the new school year has started, he is keeping to his routine. Initially, I was only doing this because I had nothing to do, he says. But it went on for so long that it became a habit. And Im proud of that. The best way to make anything stick is to build it into your everyday routine. It is much easier to do something over the long term if it becomes a habit, says Gillison. Habits occur when youve already done the decision-making, so the cue to act becomes an automatic part of your day.

She also recommends that people embark on diet or fitness changes with friends, for motivation and accountability. Social support is key, Gillison says. Finding someone to do the activity with, in person or virtually, or even just showing interest and encouraging you to keep going, is helpful, she says.

After gaining 3.6kg during lockdown, Wild has been following the NHS weight loss plan, a diet devised by doctors to help people lose weight at a safe and sustainable rate, with her husband. Ive tried to lose weight before, but it was a nightmare, making two meals and having all this tempting food around, she says. Whats been great this time is having my husband do it with me. I want to get fit for my older age, Wild says. I dont feel old at all. But I know that Covid is worse if youre older, and overweight.

Gillison warns that health anxiety is not in itself enough to sustain a long-term change: it is easy to become complacent once the initial alarm has worn off. The public will hear the message that Covid is more dangerous for the obese and it will get them out of the door a few times, she says. But unless they find something they enjoy doing, it will be a short-term fix.

The most important way to make fitness a habit is to make it fun. We are only able to make ourselves do something for a short amount of time, says Gillison. Its hard to stick at something you find unpleasant, plus you dont get the benefits in terms of the sense of wellbeing when youre doing something you dont like. So, if lockdown was a time of experimentation with various activities, pick the one you enjoyed.

Ludford is confident that he wont slip back into old ways. Ive seen such a huge change in my life, he says. Covid gave me the opportunity to focus on the things that were undermining my mental health. Im not going to go back to how things were before. Its been transformational.

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I got a whole new mindset: the health secrets of people who got much fitter in lockdown - The Guardian

Global Weight Loss and Weight Management Diets Market : Industry Analysis and Forecast (2019-2026) by Type, Application, and Region – re:Jerusalem

Posted: October 28, 2020 at 3:55 am

The global Weight Loss and Weight Management Diets market report offers an understanding of the dynamics, growth aspects, and functioning of theglobal Weight Loss and Weight Management Diets market. The report evaluates the market over the years with a comprehensive study. The Weight Loss and Weight Management Diets market assessment puts forth all-inclusive data that enriches the scope, understanding, and application of this report. Further, it provides the market competition landscape along with a thorough assessment of the key players (GlaxoSmithKline, Herbalife, Abbott Nutrition, Nestle SA, Danone, Glanbia, Kellogg Company, Pepsico, Atkins Nutritionals, Amway, NutriSystem Inc, Jenny Craig Inc, Creative Bioscience, Weight Watchers, Iovate Health Sciences, Jenny Craig, Nutrisystem) in the market.

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Weight Loss and Weight Management Diets Market Competition by Key Players/Top Manufacturers:

GlaxoSmithKline, Herbalife, Abbott Nutrition, Nestle SA, Danone, Glanbia, Kellogg Company, Pepsico, Atkins Nutritionals, Amway, NutriSystem Inc, Jenny Craig Inc, Creative Bioscience, Weight Watchers, Iovate Health Sciences, Jenny Craig, Nutrisystem, among others.

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Key parameters which define the competitive landscape of the Global Weight Loss and Weight Management Diets Market:

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The reports aim bifurcated the global Weight Loss and Weight Management Diets market based on segments and sub-segments taking into consideration their previous and forecast growth trends.

Analysis of Global Weight Loss and Weight Management Diets Market: By Type

Meal Replacement Products, OTC Obesity, Slimming Teas, Supplement Nutrition Drinks, Weight Loss Supplements, Other

Analysis of Global Weight Loss and Weight Management Diets Market: By Application

Retail Stores, Online Stores

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Chapter 2: Executive Summary of Weight Loss and Weight Management Diets Market;

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Chapter 4: Weight Loss and Weight Management Diets Market, By Region;

Chapter 5: Company Profile;

Chapter 6: to show competition and trade situation of Weight Loss and Weight Management Diets Market;

Chapter 7: to show a comparison of applications;

Chapter 8: to display a comparison of types;

Chapter 9: to present investment of Weight Loss and Weight Management Diets Market;

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COVID-19 Outbreak Analysis on Global Weight Loss and Weight Management Diets Industry

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Global Top 10 Companies Share Analysis in Weight Loss and Weight Management Diets Market

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Explore the subliminal messaging on your Halloween candys label – The Counter

Posted: October 28, 2020 at 3:55 am

Most people wouldnt pick up on these nuances, but Carlos Velasco does. A professor of marketing at the BI Norwegian Business School in Oslo, he has devoted years to studying how seemingly inconsequential features of packaginglike color, typeface, and soundcan recalibrate what we taste. Hes discovered that angular, asymmetrical fonts make us perceive foods as sour, while we tie round, symmetrical writing to sweetness. That cloud-like Airheads lettering? To your brain, its positively saccharine.If theres a case in which typeface clearly contributes to the taste, it is this one, Velasco says.

You can see this phenomenon all across the candy aisle: Reeses deploys fonts that look almost creamy. Starburst lettering seems to curl backward, like someone scrawled it across a sphere. On the flip side, companies selling sour candieslike Warheads or Brain Blasterzpackage their products with far more angularity. The writing on Brain Blasterz, a line of sour candies and candy sprays, looks claustrophobic, with sharp angles on the B andZ.

Candy companies, with their eccentric fonts and sharp flavors, offer a clear illustration of a broader shift in grocery stores. Over the last two decades, food and drink packaging has become far more scientificand companies have figured out how to use tiny details, like typeface, to guide what we taste.

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Testosterone Replacement Therapy Market 2020 Share, Size, Future Demand, Global Research, Top Leading player, Emerging Trends, Region by Forecast to…

Posted: October 28, 2020 at 3:54 am

The Global Testosterone Replacement Therapy Market report offers key insights into the worldwide Testosterone Replacement Therapy market. It presents a holistic overview of the market, with an in-depth summary of the markets leading players. The report is inclusive of indispensable information related to the leading competitors in this business sector and carefully analyzes the micro- and macro-economic market trends. The latest report specializes in studying primary and secondary market drivers, market share, the leading market segments, and comprehensive geographical analysis. Vital information about the key market players and their key business strategies, such as mergers & acquisitions, collaborations, technological innovation, and trending business policies, is one of the key components of the report.

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The report covers extensive analysis of the key market players in the market, along with their business overview, expansion plans, and strategies. The key players studied in the report include:

Furthermore, our market analysts have drawn focus to the significant impact of the COVID-19 pandemic on the global Testosterone Replacement Therapy market and its key segments and sub-segments. The grave aftereffects of the pandemic on the global economy, and subsequently, on this particular business sphere, have been enumerated in this section of the report. The report considers the key market-influencing parameters, delivering a detailed future impact assessment. The Testosterone Replacement Therapy market has been devastated by the pandemic, which has culminated in drastic changes to the market dynamics and demand trends.

In market segmentation by types of Testosterone Replacement Therapy, the report covers-

In market segmentation by applications of the Testosterone Replacement Therapy, the report covers the following uses-

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Moreover, the research report thoroughly examines the size, share, and market volume of the Testosterone Replacement Therapy industry in the historical years to forecast the same valuations over the forecast duration. It offers exhaustive SWOT analysis, Porters Five Forces analysis, feasibility analysis, and investment return analysis of the Testosterone Replacement Therapy market, assessed using certain effective analytical tools. The report also provides strategic recommendations to market entrants to help them navigate around the entry-level barriers.

The global Testosterone Replacement Therapy market is geographically categorized into:

The following timeline is considered for market estimation:

Historical Years: 2017-2018

Base Year: 2019

Estimated Year: 2020

Forecast Years: 2020-2027

Key Coverage of the Report:

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PARP Inhibitors Market set to witness surge in demand over the forecast period – The Think Curiouser

Posted: October 28, 2020 at 3:54 am

Global PARP Inhibitors Market: Introduction

A PARP (poly ADP-ribose polymerase) inhibitor is a substance that blocks PARP enzyme in the cell. DNA damage occurs during cancer. Blocking of PARP helps the cancer cells in repairing their damaged part of DNA.

Global PARP Inhibitors Market: Competition Landscape

Key players operating in the global PARP inhibitors market are AstraZeneca, Tesaro, AbbVie Inc., Medivation, and Clovis Oncology. The global market is highly consolidated, with the presence of a small number of manufacturers. Increase in strategic collaborations and new product launches are expected to drive the global PARP inhibitors market during the forecast period.

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AstraZeneca

AstraZeneca is a biopharmaceutical company engaged in the discovery, manufacture, distribution, and commercialization of biopharmaceutical products. The company is a leading player in the global pharmaceutical sector. It offers various services and products in therapeutic areas such as cardiovascular and metabolic diseases; oncology; and respiratory, inflammation, and autoimmunity (RIA). Additionally, the company provides products useful in the treatment of infections, neurologic disorders, and gastrointestinal diseases. With a high focus on research and development for certain specific aspects of neurodegenerative diseases, analgesia, and psychiatry, AstraZeneca continues to collaborate with other innovative partners across industry and academia. The areas of cognitive disorders, chronic pain, and other central nervous system disorders still experience significant unmet medical needs.

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AbbVie Inc.

AbbVie, Inc. develops and distributes pharmaceutical products worldwide. The company offers pharmaceutical products for use in testosterone replacement therapy and the treatment of hypothyroidism and autoimmune diseases. It distributes products directly to wholesalers, government agencies, distributors, health care facilities, and specialty pharmacies worldwide. HUMIRA, a biologic therapy for the treatment of autoimmune diseases, is the companys blockbuster drug. It accounted for around 63% share of the companys sales revenues in 2014. The company sells its products in more than 170 countries across the globe.

Global PARP Inhibitors Market: Dynamics

The global PARP inhibitors market is primarily driven by increase in the rates of incidence and prevalence of cancer. In addition, increase in the adoption of PARP inhibitor drugs, growth of geriatric population, and advancements in the global health care sector are expected to boost the global PARP inhibitors market in the next few years. Furthermore, the existing market players are deploying advanced techniques to come up with innovative methods for the development of technologically advanced treatments for cancer. This is likely to propel the demand for PARP inhibitors during the forecast period. However, frequent product recalls and stringent government regulations are expected to restrain the global market in the next few years.

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Increase in Incidence of Cancer Driving Global PARP Inhibitors Market

Cancer is the leading cause of death globally, after cardiovascular diseases. According to the World Health Organization (WHO), cancer accounts for 8.3 million deaths every year, with 70% new cancer cases expected to be reported in the next 20 years. Increase in the cancer-afflicted population is anticipated to be a key driver of the global PARP inhibitors market during the forecast period. According to a report by the Centers for Disease Control and Prevention (CDC) published in 2014, the number of cancer patients diagnosed in the U.S. reached approximately 21 million. The number is expected to reach 25.4 million by the end of 2024. Over 60% of the worlds new cancer cases occur in Asia, Africa, and South America. Nearly the same percentage of cancer deaths take place in these regions. Stomach, liver, lung, breast, and esophageal cancer are most prevalent worldwide.

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PARP Inhibitors Market set to witness surge in demand over the forecast period - The Think Curiouser

New virtual clinic aims to provide accessible, inclusive health care to LGBTQIA+ North Carolinians – Yes! Weekly

Posted: October 28, 2020 at 3:54 am

With the recent confirmation of Amy Coney Barrett to the United States Supreme Court on Monday night, many Americans will most likely lose their access to affordable health care in the near future. And this is particularly disturbing to North Carolinians because, for almost a decade, Republican leadership in the states legislature has refused to expand Medicaid, despite support from voters on both parties. The Center for American Progress, an independent, nonpartisan policy institute, and NORC at the University of Chicago conducted a survey with 1,528 LGBTQIA+ identifying individuals in June.

In states that have not expanded Medicaid, the rate of LGBTQIA+ adults who are uninsured is 20 percent, the results state, adding that LGBTQIA+ adults making less than $45,000 a year are the ones most prominently affected. According to this survey, transgender folks and people with disabilities bear the brunt of the high cost of health care, as 51% of transgender individuals and 40% of people with disabilities who needed medical care postponed it due to cost, and 40% of transgender individuals and 30% of people with disabilities postponed preventative screenings due to cost.

A Greensboro-based virtual clinic with a focus on LGBTQ health hopes to support those living in the margins of society by providing virtual health care services to anyone living in North Carolina. Founded by Chief Operating Officer Jamie Clarke and Chief Medical Officer Dr. Subrata John Guha, the LGBTQ Clinic was conceptualized specifically with the health care needs of LGBTQIA+ people in mind.

If you have a phone, iPad, or computer, you can come see us, Guha said. You dont have to go anywhere just be seen where you are comfortable, and take a proactive approach for your health.

According to Clark and Guhas research, there are approximately 420,000 people that identify as LGBTQIA+ in North Carolina, and of those, 30,000 identify specifically as transgender. Clarke is one of those 30,000. Unfortunately, Clarke knows all too well the barriers that other trans people face when seeking health care.

I had a lot of problems getting comfortable, comprehensive medical care, she said. Not just about [Hormone Replacement Therapy] or sexual health, but about Jamie as a whole person, which encompasses all of those things and my day-to-day medical needs.

She said that the LGBTQIA+ community, as a whole, are not very trusting of doctors. As a transgender woman, she has experienced first-hand what that is like to be treated differently because of her gender identity. At age 35, Clarke decided that she wanted to begin transitioning by starting HRT, so like any other patient, she asked her doctor for more information.

I was dealing with a local doctor and asked to have my hormone levels checked, as I was getting bloodwork done anyway, she said. And they were like, well, why would you want to do that? And I was like, so I can start HRT, and she said, Oh, I am not comfortable doing that.

This experience led Clarke to switch to Dr. Guha. During her interview with him, she felt comfortable enough to ask about starting HRT because he was honest, straightforward, and extremely easy to talk to.

Clarke said when she told him that she was interested in starting HRT, he told her that he wasnt too familiar with it, so he had to do some more research to make sure he was doing it properly.

As we got to know each other, I was explaining to him that sometimes, I was at the point where I wanted to go online and figure out how to do it myself. But he was like thats probably not safe, Clarke said. And there are a whole lot of people that are in that exact boat. So, we are trying to take the stigma out of LGBTQIA+ health.

With The LGBTQ Clinic, Clarke and Guha said they are trying to create a movement toward community-based, equalized health care by building relationships with clients in a convenient and accessible format.

In the telemedicine space, typically what you get is a five-minute visit, sometimes not even by video but as a phone call, Clarke said. Our visits are 15 minutes long, and we strongly encourage getting to know your doctor, and vice versa, because you always get the same care provider.

Clarke described the LGBTQ Clinic as everything one would expect at a visit to their regular health care provider, only virtually.

One of our marketing specialists was like, think about it as going to the doctors office, not getting deadnamed, and you dont have to sit on the crunchy paper in a germ pool, Clarke said.

Guha explained that the LGBTQ Clinic could basically replace ones primary care doctor because it is all-encompassing and that everyone, not just LGBTQIA+ people, could receive health care services.

I can write a virtual prescription to your pharmacist, any pharmacist we are basically like walking into your doctors office but all virtual, Guha said. We cant administer shots, but if it can be self-administered, then I can prescribe it, and you can pick it up.

However, Guha said he makes sure he is thorough with each patient he sees.

When someone comes in, I dont just write a prescription for testosterone, he said. I want that lab work, and I would want to see the patient again after the lab work [results came back] to go over it and then provide the prescription.

The LGBTQ Clinic isnt Guhas first foray into providing fast and accessible health care services to people. Guha said he helped start FastMed back in the ancient ages of 2010, but sold out of it in 2014-2015 after the business was acquired by a venture capitalist. As a heterosexual, cisgender man, Guha said he believes that everyone should have the same access to health care and be treated equally, which is why he was more than happy to help start this clinic.

Guha takes pride in his informed approach to LGBTQIA+ health, as he follows the guidelines put out by the University of California at San Francisco and its Department of Internal Medicines sub-department, which is specifically tailored for the LGBTQIA+ community.

In the last five years, this premier medical center started putting out clinical protocols that established guidelines and state of the art, the scope of practice protocols, he noted.

Launching the LGBTQ Clinic hasnt been easy but has been a labor of love for both Clarke and Guha.

We are really excited about it, she said. Being in Greensboro, and with it being such a large college town, the need is absolutely there. One of the hardest things we are having problems with is trying to have conversations with influencers or people that can get the message out for us. I dont want to be a sponsored ad; I want to be a trusted resource.

Clarke said North Carolinas 2016 controversial Bathroom Bill was a big part of their discussion, and it was a driving factor as to why we would create this clinic specifically.

We dont have time for the noise, Clarke said of the recent politicizing of health care. We just want to provide quality health care to as many people that need it as we can...Its also about bringing some respectability to a state like North Carolina, where there is a lot of uncertainty about this particular issue.

Whoever is elected president in November, we will still be here, she added.

Clarke said each 15-minute virtual session costs $78 per visit, which she said is cheaper than the $150 that is usually charged by the local larger medical centers.

We are looking to do a subscription plan, but because we are so new, we are still testing the market, Guha said, adding that The LGBTQ Clinic will soon accept insurance coverage from Blue Cross Blue Shield of North Carolina, Cigna, United Care, and others.

We are actively pursuing the credentialing process, and its just a waiting game, Clarke said.

I am guessing in the next 30-60 days, and the reason why it is taking so long, as you probably already know, is because of COVID, Guha added.

Presently, there are two doctors (including Guha) and one nurse practitioner on staff at The LGBTQ Clinic. Clarke said she is looking for support from local LBGTQIA+ community leaders but makes it clear that they are not trying to buy their way into the community. Clarke and Guha said they arent in the business of just making a quick buck; they want to establish the LGBTQ Clinic as a long-term resource.

Health care should not be any different or any less quality because you are in the LGBTQ community, she said. We are trying to provide and be a voice to the movement. With a 30-veteran of the health care industry to say that your health care is no different or more valuable than anyone elses, that is the real distinction here.

For more information, visit the website and follow The LGBTQ Clinic on social media (Instagram and Facebook, @lgbtq.clinic)

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New virtual clinic aims to provide accessible, inclusive health care to LGBTQIA+ North Carolinians - Yes! Weekly

Weight loss supplements: Are they effective? – Science World Report

Posted: October 28, 2020 at 3:53 am

First Posted: Oct 26, 2020 01:35 PM EDT

(Photo : pixabay)

If you find maintaining a healthy weight difficult, you can take comfort in knowing that you are not alone. According to a study published by The Institute for Health Metrics and Evaluation (IHME), an independent population health research institute in Seattle, WA, over 160 million people in America are either overweight or obese. And many of these same individuals are struggling with health problems related to their weight.

As a matter of reference, the National Institutes of Health noted that individuals who are overweight are obese are more likely to develop high blood pressure, high cholesterol, and cardiovascular disease. Excess weight can also lead to elevated blood glucose levels, which, in turn, can give way to diabetes, the study further noted. If there is a silver lining in all of this, it is that more people are taking steps to safeguard their health by losing weight.

Traditional Ways to Lose Weight

There are just as many ways to lose weight as there are people who are overweight or obese. And the argument could be made that some ways are better than others. Along with exercise, many individuals will choose one of many popular diets to shed unwanted pounds, some of which include the Mediterranean and Weight Watchers, both of which were named the best diets of 2020 by U.S. News and World Report.

While these diets are great, some people find that they don't lose much weight following them. And the weight that they did lose didn't stay off for very long. For these reasons, many people turn to dietary supplements to help them shed unwanted pounds, with some of the more notable ones being green tea extract, vitamin D, glutamine, caffeine, and raspberry ketone supplements.

How Effective are Mainstream Diets and Supplements?

If you're among the over 160 million people in America trying to lose weight, you might be curious about the success rate when it comes to mainstream diets and supplements. And if so, you might find this information interesting. A recent study found that individuals following a Mediterranean diet, a diet low in saturated fats and carbohydrates, lost as much as 22 pounds in one year.

A separate study related to the Weight Watchers diet noted found that most individuals were able to lose approximately 8 percent of their body weight in 6 months. However, it is worth mentioning that only 11 percent of those who followed this diet managed to keep the weight off long-term, according to Dennis Gage, a physician with Park Avenue Endocrinology and Nutrition in New York City. Rounding things out with dietary supplements, a study published by the Mayo Clinic found that individuals who took dietary supplements, namely raspberry ketones, lost about 4.2 pounds in 8 weeks.

Scientific Studies Reveal a Revolutionary Way to Lose Weight

For those who have tried to lose weight by exercising, dieting, and taking supplements but have been unsuccessful, you should know that all hope is not lost, especially for individuals age 40 and over. Current data shows that most middle-aged individuals have low human growth hormone (HGH) levels. Of course, this is not entirely surprising given that HGH levels gradually start declining from the age of 30.

For those who are perhaps not aware, one of the ill-effects of low growth hormone levels is an increase in visceral fat, especially around the abdomen. For many middle-aged individuals, visceral fat makes up the majority of their excess weight. What's more, it is a form of body fat that generally does not come off easily.

That said, science has identified a new supplement known as Resurge that could very well be the answer for older adults who are overweight or obese and want to slim down. There is also evidence that shows it could help younger individuals shed unwanted pounds as well.

But, it would be fair enough to say, that for people with tested and proven human growth hormone deficiency the most effective type of treatment is hgh injections with such brands as Genotropin, Norditropin, or Humatrope which is affordable enough in costs around US.

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Weight loss supplements: Are they effective? - Science World Report


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