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Why Beyonc’s Fans Are Obsessed With Her Guacamole Recipe – Showbiz Cheat Sheet

Posted: June 14, 2020 at 5:49 am

Beyonc is one of the most famous women in the world with one of the most loyal fan bases of any artist in the modern era. Members of the Beyhive are interested in many aspects of the singers life from her marriage to Jay-Z to what her beauty routine is to what she eats and drinks on a daily basis.

When it comes to her diet and favorite foods, the songstress has revealed a bit about her eating habits over the years as well as how she makes guacamole. Read on to find out what foods Queen Bey eats and why the Beyhive is obsessed with her guacamole recipe.

RELATED: How Is Beyonc Related To Queen Elizabeth II?

In 2018, before headlining Coachella, Beyonc announced via Instagram that she was going back on a vegan diet to get fit for the big performance. Bey tried the diet with her husband a few years before as well.

The benefits of a plant-based diet need to be known. We should spend more time loving ourselves, which means taking better care of ourselves with good nutrition and making healthier food choices, the Formation artist explained.

Beyonc doesnt stick to a vegan diet all the time but she still watches what she eats and previously talked about what her other meals consist of during an interview with Shape Magazine.

I always have breakfast, say, scrambled egg whites, a vegetable smoothie, or whole-grain cereal with low-fat milk. For lunch and dinner, I eat a lot of fish and vegetables, she said, adding that she sometimes replaces rice and pasta with quinoa for a low-calorie diet.

In addition to wanting to know about Beyoncs diet, some became curious about if she enjoys cooking and has any homemade recipes to recommend.

Well, we can tell you that recipe writing isnt really Beyoncs thing. However, a few years back she did share how she makes guacamole and since then many of her fans have tried and now cherish it because its the one and only recipe Bey has ever published.

If you still havent tried Beyoncs famous guac recipe theres no need to wait any longer. Its so easy to prepare, yet its sure to impress every guest.

To make the guacamole at home youll need these ingredients:

Then follow Beys instructions:

Related: How to Make Kris Jenners Layered Guacamole That the Kardashian-Jenner Sisters Go Crazy Over

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Why Beyonc's Fans Are Obsessed With Her Guacamole Recipe - Showbiz Cheat Sheet

Why adding more fibre to your diet is a good idea – your body will thank you – Health24

Posted: June 14, 2020 at 5:49 am

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Incontinence can refer to the involuntary leaking of urine (urinary incontinence, which signifies a problem with the bladder) or faeces (faecal incontinence, which points to an underlying problem in the bowels).

Both can be equally debilitating and embarrassing, but there is no reason why both urinary and faecal incontinence cant be managed. Your diet as one of many lifestyle factors is often overlooked when it comes to managing incontinence. And there is one component of your diet that may help manage both urinary and faecal incontinence.

Why your body needs fibre

Fibre, an important yet underrated part of any healthy diet, plays a key role in the way your body functions. This is the indigestible part of fruits, vegetables, grains, beans and legumes and is key in keeping your digestive system healthy.

As fibre absorbs water, it helps to keep us fuller for longer, and helps to lower cholesterol and blood glucose levels, which can help prevent conditions such as hypertension, high cholesterol, cardiovascular problems and diabetes.

Fibre and the bowels

But if fibre is meant to make your bowel movements more regular, isnt this defeating the purpose of helping to manage faecal incontinence?

Actually, quite the opposite.

When dietary fibre is not digested, it adds more bulk to the stools, which helps you stay more regular and avoid constipation, which can lead to faecal incontinence. Chronic constipation may lead to faecal incontinence, as the constant strain on the rectum can damage the surrounding nerves.

As the rectum and intestinal muscles stretch from too much straining to pass stool, they can eventually become weak, which allows the watery stool deeper in your intestines to seep through.

As fibre absorbs water, it can also bulk up faecal matter, which causes less watery stool.

Fibre and the bladder

Although we dont associate what we eat with bladder health, diet can have an effect on the severity of urinary incontinence, which is usually the symptom of an underlying cause such as nerve damage.

Being overweight or obese can increase the risk of urinary incontinence. Fibre is an important aspect of weight management and a healthy balanced diet, as it keeps us fuller for longer. Therefore, including fibre in your diet can indirectly increase your overall health and improve your weight, which is important in the management of urinary incontinence.

But the bowels and constipation can also cause urinary incontinence when bowel movements are strained, extra pressure is placed on the pelvic floor muscles, which can weaken them and affect bladder control. This is referred to as stress incontinence.

A full bladder can also cause pressure, leading to urge incontinence, which makes you feel the need to urinate frequently, or cause your bladder to leak. This is referred to as overflow incontinence.

If you are experiencing urinary incontinence, its important to discuss with your doctor whether you are also experiencing chronic constipation, as these two conditions can be linked.

How to include more fibre in your diet

If you suspect that you are not eating enough fibre, its important not to overdo it in the beginning, as too much fibre can cause unwanted side-effects such as bloating and gas. If you suffer from any food allergies or conditions such as irritable bowel syndrome, you should also discuss this with your doctor or a registered dietitian to help you determine a way to eat more fibre.

Here are ways to gradually add more fibre to your diet:

According to the Simon Foundation for Continence, fibre therapy is a great way to alleviate incontinence and increase your overall health. This should, however, not be seen as a complete cure, and other treatment options and management methods under the guidance of a healthcare provider should also be considered.

READ | 5 reasons why you need to pee all the time

READ | Caregiving in the time of Covid-19: Can coronavirus spread through urine?

READ | What your bladder is trying to tell you about your health

Image credit: Nathan Cowley from Pexels

Marelize Wilke

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Why adding more fibre to your diet is a good idea - your body will thank you - Health24

Ashwagandha: 8 Reasons To Include It In Your Diet – NDTV Doctor

Posted: June 14, 2020 at 5:49 am

Ashwagandha is a powerful herb with medicinal properties. It has been used as part of traiditional Ayurvedic medicine to boost memoery. Here are the health benefits of including this herb in your diet.

Ashwagandha is known to offer multiple health benefits

Ashwagandha is a medicinal herb with some remarkable health benefits. Not only can it help in combat stress, it can also benefit the body and brain in multiple ways. Reducing symptoms of anxiety and depression, lowering blood sugar and improving brain function are a few of the many ways how ashwagandha can help you. An interesting way to include ashwagandha in diet to add its power in honey and warm milk at bedtime.

1. Blood sugar: Ashwagandha can increase insulin secretion and improve insulin sensitivity. This can help in reducing blood sugar levels, which may in turn be helpful for people with diabetes.

2. Cortisol: The medicinal herb has been found to reduce cortisol levels. It can be especially helpful for people with chronic stress, depression and anxiety.

Also read:Lockdown Stress: 6 Quick And Simple Ways To Make You Feel Better

3. Depression: A few studies have shown that ashwagandha can help in alleviating depression. More research is needed to testify this claim.

4. Fertility: Supplements of ashwagandha can have powerful effects on testosterone levels and reproductive health. It can boost sperm quality and improve fertility in men.

Also read:Male Fertility: 6 Most Useful Herbs

5. Muscle mass and strength: Regular intake of ashwagandha can help in improving body composition and increase body strength. So for those focusing on gaining muscle mass, including ashwagandha in diet can be beneficial.

6. Inflammation: Ashwagandha can reduce markers of inflammation like C-reactive protein (CRP). This marker has been linked to an increase in risk of heart disease.

7. Cholesterol: Cholesterol reducing properties of ashwagandha is another reason why the herb can be beneficial for people with heart disease.

8. Brain function and memory: Ashwagandha can mitigate memory and brain function problems caused by injury or disease. In traditional Ayurvedic medicine, ashwagandha has been used traditionally to boost memory.

Ashwagandha can improve brain function and memoryPhoto Credit: iStock

Pregnant and breastfeeding women and people with autoimmune diseases must include ashwagandha in diet only if it has been recommended by their health expert. Also, if you have thyroid issues should talk to their doctor about it as the herb may increase thyroid hormone levels in some people, reports healthline.com. All in all, the herb is fairly safe to consume.

Disclaimer: This content including advice provides generic information only. It is in no way a substitute for qualified medical opinion. Always consult a specialist or your own doctor for more information. NDTV does not claim responsibility for this information.

DoctorNDTV is the one stop site for all your health needs providing the most credible health information, health news and tips with expert advice on healthy living, diet plans, informative videos etc. You can get the most relevant and accurate info you need about health problems like diabetes, cancer, pregnancy, HIV and AIDS, weight loss and many other lifestyle diseases. We have a panel of over 350 experts who help us develop content by giving their valuable inputs and bringing to us the latest in the world of healthcare.

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Ashwagandha: 8 Reasons To Include It In Your Diet - NDTV Doctor

How to live longer – how many bananas should you eat every week? – Express

Posted: June 14, 2020 at 5:49 am

Maintaining a healthy lifestyle, including a well-rounded diet is crucial to prolonging your lifespan.

You could also boost your lifespan by doing regular exercise. Its the miracle cure weve all been waiting for, according to the NHS.

Making some small diet or lifestyle changes could help to increase your life expectancy and avoid an early death.

But eating bananas could be one of the easiest ways to boost your overall health, it's been revealed.

READ MORE: How to live longer - one behaviour may add years to your life

"Whether you like your bananas slightly green or freckly, they all come with triple levels of mood-boosting powers," they said in their book 'Eat Better Live Longer - Understand What Your Body Needs To Stay Healthy'.

"They are good sources of carbohydrates [fuel for the brain and muscles], and of tryptophan and vitamin B6 [both of which are needed for production of feel-good chemicals].

"Whats more, bananas improve digestion and may help regulate blood pressure.

"Bananas will ripen at home - if you want to speed up the process, keep them in a bunch or with other fruits."

Eating bananas could also make you feel fuller for longer, as theyre rich in a fibre called pectin, the nutritionists added.

Everyone should aim to eat between three and four bananas every week, they said.

Raw bananas provide the highest nutrient benefits.

While everyone has their own preference for whether they like their bananas yellow or green, their nutrients vary depending on their ripeness.

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How to live longer - how many bananas should you eat every week? - Express

Seven models lift the lid on their lockdown workouts and diet secrets – Mirror Online

Posted: June 14, 2020 at 5:49 am

If you fancy the body of a supermodel, weve got you covered.

Some of the worlds hottest pin-ups have lifted the lid on their lockdown workouts and diet secrets.

Swapping runway frocks for leggings, these stunning celebrities have opened up their home gyms and kitchens to fans across the globe.

From gruelling home workouts to wholesome smoothies and balanced breathing, we look at how the worlds A-list beauties are staying in sparkling shape for when the catwalks reopen without getting a hair out of place.

Kate shot to fame after appearing on the Sports Illustrated Swimsuit issue in 2011 and was the cover model for the magazine in 2012, 2013 and 2017.

The mum from Michigan, US, keeps her fabulous figure using her own 12-week workout, Strong4Me.

Created with personal trainer Ben Bruno, it focuses on low-impact exercises in 30-minute sessions, using minimal equipment. Kate, 28, is turning this time into an opportunity to better myself mentally and physically.

She easily tops the cuteness stakes exercising with daughter Genevieve, one. Lunging with her in her arms, she says: My baby girl is my favourite addition to my workout."

Vogue favourite Cindy is known for her dazzling presence on magazines the world over, as well as her runway work and fashion campaigns for the likes of Chanel, Versace, Dolce & Gabbana and Christian Dior.

Since lockdown, she has been reliving her supermodel heyday of the 1980s and 90s by posting her old workout videos on social media.

Cindy, 54, says: While were all home and trying to keep up with Facetime workouts, I figured this might be a good time to bring all of my videos out of the archives.

I still love Radus philosophy of working with what you have and pushing yourself. She is also a huge advocate of healthy eating, helping her stay a slim size eight.

In one post, the US model treats us to a glimpse of her favourite home smoothie recipe which includes almond milk, frozen bananas, spinach, mint and protein.

Naomi, 50, has been in the game since being scouted while window shopping in Covent Garden at 15.

So its no surprise the London-born model has a few tricks for staying in shape during lockdown.

She tells her YouTube followers about her supplements regime, and posts 45-minute workouts on Instagram with personal trainer Joe Holder. The daily sessions include bodyweight exercises, vibration plates and resistance bands.

Her chef Sean John recently revealed the model eats no dairy, gluten or chicken.

If you want to eat like a world-famous model, look no further than Chrissy Teigens Instagram.

The mum of two has a 25in waist and graced the cover of Sports Illustrateds famed swimsuit issue.

She has an Instagram dedicated to her food cravings. She admits exercise can suffer if youre a mum.

One post said: Worked out for 5 mins today! Proud as, according to math, 5 is more than 0."

Cara, who has spoken openly about struggles with her mental health, has turned to yoga to help her through lockdown.

London-born Cara, 27, says: Ive been using yoga to keep my body moving and my head clear during this crazy time.

Speaking to yoga expert Colin Dunsmuir, who runs the classes Cara shares online, she told him how the sessions left her calm and thoughtful but not overthinking. Cara, 5ft 8in with a 24in waist, has been working with sports brand Puma to treat her fans to the live online workouts.

And the gentle moves arent too strenuous she is seen in a cross-legged easy pose, stretching to her toes and deep breathing.

Australian Miranda rose to prominence in 2007 as one of the Victorias Secret Angels renowned across the world for their jaw-dropping bodies.

And she has been using her time in isolation to prove that self-care is key to true beauty.

Every week Miranda has engaged fans with a Wellness Wednesday making her own face masks, posting workout videos and showing off some of her favourite recipes.

She constantly encourages her viewers to get involved and reap the benefits for themselves.

Luckily, all youll need is a yoga mat and motivation, as most of the 35-minute sessions focus on body weight exercises.

For those with a sweet tooth she has also posted healthy recipes such as vegan banana oatmeal cookies, using gluten-free flour, cinnamon, bananas and chocolate chips.

Showing off her body in a sexy bikini is all in a days work for a Victorias Secret model like Brazilian Izabel.

So its no wonder she makes her workout regime as rigorous as she possibly can.

From pull-ups in doorways to handstands on walls and solo-boxing, Izabel has been making the most of the opportunities around her home.

And it seems all the hard work continues to pay off the stunning 35-year-old is 5ft 10in with an astounding 23in waist.

And Izabel is not about to let her followers off the hook either, telling them there are no excuses for not pushing yourself to train as best as you can even during a pandemic.

The supermodel has previously revealed that she works out for an hour every day, using a mixture of Pilates, kickboxing, yoga, running and full-body resistance training.

She makes it all so appealing, even her friends young daughter wants a slice of the action.

While Izabel carries her on the treadmill, they share ab exercises and hip raises. Her adorable mini-me makes this workout seem like childs play.

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Seven models lift the lid on their lockdown workouts and diet secrets - Mirror Online

Drinking 100% fruit juice can have long-term dietary benefits, says study – The Indian Express

Posted: June 14, 2020 at 5:49 am

By: Lifestyle Desk | New Delhi | Published: June 10, 2020 9:40:13 pm Fruit juice has many health benefits. (Source: getty images)

Drinking 100 per cent fruit juice in the early years can lead to healthier diet patterns later in childhood, without adversely impacting weight gain.

In a study by Boston University, published in the journal BMC Nutrition, researchers found that drinking fruit juice meant higher intake of whole fruit as well as better diet quality through childhood and into middle adolescence.

This research provides important information showing that children who consumed about 1.5 cups of 100 per cent fruit juice per day during the preschool years tended to maintain healthier diets into adolescence than children who drank less than 1/2 cup per day during preschool, lead researcher Lynn L Moore said in a statement.

Read| ABC for health: Why apple, beetroot and carrot juice is good for immunity

In addition, over 10 years of follow-up, juice consumption within the range typically consumed by these children (1-2 cups per day), was not associated with excess weight gain during childhood, Dr Moore added.

From the study, researchers inferred that preschoolers with higher intake of 100 per cent fruit juice had significantly higher intakes of whole fruit and total fruit at 14-17 years of age than those children who consumed lesser juice.

Read| Start your day with watermelon this summer; heres why

It was further found that children with higher fruit juice intake during preschool years had significantly higher diet quality as compared to those with lower intake at all ages.

Fruit consumption, particularly whole fruit consumption, has many health benefits throughout the lifespan. Avoiding juice during these early formative years may have unintended effects on evolving dietary behaviorsThese benefits, associated with moderate intakes of 100 per cent fruit juice, were not accompanied by any adverse effects on childhood weight, the researcher said.

(With inputs from ANI)

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Drinking 100% fruit juice can have long-term dietary benefits, says study - The Indian Express

How Ayurveda can help you stay healthy: Expert’s tips to improve skin, hair, and diet through natural medicine – Times Now

Posted: June 14, 2020 at 5:49 am

How Ayurveda can help you stay healthy: Expert's tips to improve skin, hair, and diet through natural medicine  |  Photo Credit: iStock Images

New Delhi: The natural mechanism of our body is such that it adjusts to the weather. However, hot and humid weather can cause oily and itchy skin, tanning, and sweating. It can also result in body odour. Hair and digestive problems also become common during the summer season. Unrestricted sun exposure, even during monsoon, can cause premature ageing in all skin types whileoily skin may experience heavy breakouts. Your hair, nails, lips, and eyes, as well as your digestive system, can get affected in the hot and humid weather. Therefore, we need to take care of our skin and limit exposure to the sun, and at the same time, take care of overall health in a natural way.

Our face is the first thing people notice and it seems that the sunrays are no different. Therefore, this part of the body bears the brunt, quite literally. Make sure you are washing you face more with plain water for 3-4 times every day. Not only it helps your body to cool off, it takes off the dirt and grime that clog the pores and prevent thesweat glands from working. Unless these glands work, your skin will not breathe and therefore, will not be healthy. You must also use a natural exfoliator to make sure dead skin cellsare off your face. You may use a homemade mix of gram flour and curd. If you have acne-prone skin, use a mix containing fullers earth (Multani mitti), sandal, rose water and basil. For dry and matured skin, choose egg white, lemon, sandal and curd with a pinch of turmeric and gram flour. However, if you have a sunburn or eruption or broken skin, wait for the area to heal before applying anything.

Though oil is not advisable for your hair during this time of the year, they are perfectly suited to cover your skin and protect it from harmful sun rays, just like SPF in sunscreen lotions. Many consider sunscreens redundant in monsoon but it prevents your skin from unwanted heat. Sunscreens available in the market are said to contain chemicals such as oxybenzone that leave an adverse impact on the hormones. Few indicative natural alternatives of SPF are:

Due to sweat, ambient humidity and dirt, our hair looks dull and limp in monsoon. Many of us also experience more dandruff. While using lemon is an age-old and tested method, fenugreek or methi seeds are also effective in resolving dandruff. It is not advisable to shampoo your hair very frequently as it takes out moisture and dries the scalp. But make sure you wash your hair with a mild shampoo. If you have an oily scalp, avoid using oil of any kind. Those who experience hair fall during monsoon can apply a natural mask of neem paste, a paste of hibiscus flower and leaves, powdered amla, reetha, shikakai, and eggs. Apply this from root to end of the hair, leave for an hour and wash off with a mild shampoo.

Sultry weather during monsoon often makes it difficult to digest the food we eat and result in food poisoning and indigestion. Eat light as eating rich, spicy food and leave some room in your stomach. Maintain a routine for meals and take small frequent meals instead of one or two heavy meals. At night, make sure your diet is light but has enough nutrition. Seasonal fruits and vegetables are the best way to beat a seasonal disease. Run your blender if you are short of time fresh juice of fruits and vegetables are a good alternative and give an equal amount of nutrition and keep you hydrated. Drink plenty of water, tender coconut water to avoid dehydration caused by endless sweating, but avoid alcohol and cold drinks. Mix some sugar and salt with plain water this will help maintain hydration and ensure electrolyte balance in your body.

Dr Bhushan Bhavsar is a guest contributor. Views expressed are personal.

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How Ayurveda can help you stay healthy: Expert's tips to improve skin, hair, and diet through natural medicine - Times Now

Novel oral testosterone therapy shows liver health benefits – Urology Times

Posted: June 13, 2020 at 10:52 am

A novel lymphatically delivered oral testosterone undecanoate (Tlando) is a fixed-dose, well-tolerated, and effective treatment for hypogonadism with liver health benefits that clearly differentiate it from the potentially hepatotoxic oral methyltestosterone, reported Irwin Goldstein, MD, at the American Urological Association 2020 Virtual Experience.

This innovative product has exciting, paradigm-shifting potential for treating men with low testosterone, said Goldstein, director of Sexual Medicine at Alvarado Hospital in San Diego, California, and clinical professor of surgery at the University of California San Diego.

It offers the opportunity to provide safe, effective, and well-tolerated testosterone replacement through the oral route that is the generally preferred method for medication administration. In addition, available data indicate that it not only avoids the adverse hepatic effects that have historically limited use of oral testosterone, but it improves markers of nonalcoholic fatty liver disease [NAFLD] that is a serious and prevalent condition. Low testosterone (ie, hypogonadism) is common in males with NAFLD.

Methyltestosterone is prone to cause liver toxicity with oral ingestion because it is directly transported to the liver through the portal vein, Goldstein said. In contrast, the lymphatically delivered oral testosterone undecanoate is a nonmethylated prodrug of endogenous testosterone, found in Tlando, that avoids first-pass metabolism in the liver and enters the systemic circulation via the lymphatics.

The safety and efficacy of Tlando for treating men with low testosterone was investigated in the 1-year SOAR trial that included 210 men who received the investigational product and a control group of 105 patients treated with topical testosterone gel.

Results from SOAR showed that the oral testosterone undecanoate was associated with a significantly greater increase in free testosterone levels compared with the topical product, and it improved key mental and sexual domains, reported Goldstein, who was an investigator in SOAR and an earlier dosing study.

Safety data in the study included measurement of liver enzymes and showed that reductions were consistently achieved in alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, and -glutamyl transferase among men who had elevated levels of those markers of liver injury at baseline. Rates of normalization for those 4 enzymes ranged from 31% for -glutamyl transferase to 67% for alkaline phosphatase.

40% reduction in liver fat at 4 months

Additional data on the liver effects of the novel testosterone undecanoate product were obtained in a smaller separate trial of men with hypogonadism. Using the objective Magnetic Resonance Imaging Proton Density Fat Fraction technique to measure liver fat percentage, it found that after 4 months, men with NAFLD at baseline achieved an approximately 40% reduction in liver fat. In addition, more than 75% of men who entered the study with NAFLD were considered responders to the oral testosterone undecanoate based on achieving a 30% or greater reduction in the percentage of liver fat.

In addition, the percentage of patients categorized as NAFLD-free rose during the study and nearly doubled by its conclusion, increasing from 34% at baseline to reach 63% at 16 weeks.

Interestingly, the higher the baseline body mass index, the greater the reduction in liver fat achieved with Tlando treatment, and it appears that the improvement in liver fat does not appear to be explained by any decrease in body weight, Goldstein said.

Disclosures: Lipocine Inc provided funding for the study. Goldstein is on the consultant/advisory board of Lipocine Inc, does research for AbbVie Inc and Marius Pharmaceuticals LLC, is on the Clarus Therapeutics, Inc speakers bureau, and receives writing support from Endo International.

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Novel oral testosterone therapy shows liver health benefits - Urology Times

Testosterone Replacement Therapy Market Overview and Outlook Report by 2026 – Weekly Wall

Posted: June 13, 2020 at 10:52 am

Testosterone Replacement Therapy

In a recent study published by QY Research, titled Global Testosterone Replacement Therapy MarketResearch Report, analysts offer an in-depth analysis of the global Testosterone Replacement Therapy market. The study analyzes the various aspects of the market by studying its historic and forecast data. The research report provides a Porters five force model, SWOT analysis, and PESTEL analysis of the Testosterone Replacement Therapy market. The different areas covered in the report are Testosterone Replacement Therapy market size, drivers and restraints, segment analysis, geographic outlook, major manufacturers in the market, competitive landscape, value/volume data, marketing strategies, and expert views

Major Key Player operating in this report are: AbbVie, Endo International, Eli lilly, Pfizer, Actavis (Allergan), Bayer, Novartis, Teva, Mylan, Upsher-Smith, Ferring Pharmaceuticals, Kyowa Kirin, Acerus Pharmaceuticals

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Segmental Analysis

The report has classified the global Testosterone Replacement Therapy industry into segments including product type and application. Every segment is evaluated based on growth rate and share. Besides, the analysts have studied the potential regions that may prove rewarding for the Testosterone Replacement Therapy manufacturers in the coming years. The regional analysis includes reliable predictions on value and volume, thereby helping market players to gain deep insights into the overall Testosterone Replacement Therapy industry.

Global Testosterone Replacement Therapy Market Segment By Type:

, Gels, Injections, Patches, Other

Global Testosterone Replacement Therapy Market Segment By Application:

, Hospitals, Clinics, Others Key Players: The Key manufacturers that are operating in the

In terms of region, this research report covers almost all the major regions across the globe such as North America, Europe, South America, the Middle East, and Africa, and the Asia Pacific. Europe and North America regions are anticipated to show an upward growth in the years to come. While Testosterone Replacement Therapy market in Asia Pacific regions is likely to show remarkable growth during the forecasted period. Cutting edge technology and innovations are the most important traits of the North America region and thats the reason most of the time the US dominates the global markets. The keyword market in the South, America region is also expected to grow in the near future.

Competitive Landscape

It is important for every market participant to be familiar with the competitive scenario in the global Testosterone Replacement Therapy industry. In order to fulfil the requirements, the industry analysts have evaluated the strategic activities of the competitors to help the key players strengthen their foothold in the market and increase their competitiveness.

Key companies operating in the global Testosterone Replacement Therapy market include: AbbVie, Endo International, Eli lilly, Pfizer, Actavis (Allergan), Bayer, Novartis, Teva, Mylan, Upsher-Smith, Ferring Pharmaceuticals, Kyowa Kirin, Acerus Pharmaceuticals

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What are the key challenges that the global Testosterone Replacement Therapy market may face in the future?

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Finally, the global Testosterone Replacement Therapy Market is a valuable source of guidance for individuals and companies. One of the major reasons behind providing market attractiveness index is to help the target audience and clients to identify the several market opportunities in the global Testosterone Replacement Therapy market. Moreover, for a better understanding of the market, QY Research has also presented a key to get information about various segments of the global Testosterone Replacement Therapy market.

Tables of ContentTable of Contents 1 Testosterone Replacement Therapy Market Overview1.1 Product Overview and Scope of Testosterone Replacement Therapy1.2 Testosterone Replacement Therapy Segment by Type1.2.1 Global Testosterone Replacement Therapy Sales Growth Rate Comparison by Type (2021-2026)1.2.2 Gels1.2.3 Injections1.2.4 Patches1.2.5 Other1.3 Testosterone Replacement Therapy Segment by Application1.3.1 Testosterone Replacement Therapy Sales Comparison by Application: 2020 VS 20261.3.2 Hospitals1.3.3 Clinics1.3.4 Others1.4 Global Testosterone Replacement Therapy Market Size Estimates and Forecasts1.4.1 Global Testosterone Replacement Therapy Revenue 2015-20261.4.2 Global Testosterone Replacement Therapy Sales 2015-20261.4.3 Testosterone Replacement Therapy Market Size by Region: 2020 Versus 2026 2 Global Testosterone Replacement Therapy Market Competition by Manufacturers2.1 Global Testosterone Replacement Therapy Sales Market Share by Manufacturers (2015-2020)2.2 Global Testosterone Replacement Therapy Revenue Share by Manufacturers (2015-2020)2.3 Global Testosterone Replacement Therapy Average Price by Manufacturers (2015-2020)2.4 Manufacturers Testosterone Replacement Therapy Manufacturing Sites, Area Served, Product Type2.5 Testosterone Replacement Therapy Market Competitive Situation and Trends2.5.1 Testosterone Replacement Therapy Market Concentration Rate2.5.2 Global Top 5 and Top 10 Players Market Share by Revenue2.5.3 Market Share by Company Type (Tier 1, Tier 2 and Tier 3)2.6 Manufacturers Mergers & Acquisitions, Expansion Plans2.7 Primary Interviews with Key Testosterone Replacement Therapy Players (Opinion Leaders) 3 Testosterone Replacement Therapy Retrospective Market Scenario by Region3.1 Global Testosterone Replacement Therapy Retrospective Market Scenario in Sales by Region: 2015-20203.2 Global Testosterone Replacement Therapy Retrospective Market Scenario in Revenue by Region: 2015-20203.3 North America Testosterone Replacement Therapy Market Facts & Figures by Country3.3.1 North America Testosterone Replacement Therapy Sales by Country3.3.2 North America Testosterone Replacement Therapy Sales by Country3.3.3 U.S.3.3.4 Canada3.4 Europe Testosterone Replacement Therapy Market Facts & Figures by Country3.4.1 Europe Testosterone Replacement Therapy Sales by Country3.4.2 Europe Testosterone Replacement Therapy Sales by Country3.4.3 Germany3.4.4 France3.4.5 U.K.3.4.6 Italy3.4.7 Russia3.5 Asia Pacific Testosterone Replacement Therapy Market Facts & Figures by Region3.5.1 Asia Pacific Testosterone Replacement Therapy Sales by Region3.5.2 Asia Pacific Testosterone Replacement Therapy Sales by Region3.5.3 China3.5.4 Japan3.5.5 South Korea3.5.6 India3.5.7 Australia3.5.8 Taiwan3.5.9 Indonesia3.5.10 Thailand3.5.11 Malaysia3.5.12 Philippines3.5.13 Vietnam3.6 Latin America Testosterone Replacement Therapy Market Facts & Figures by Country3.6.1 Latin America Testosterone Replacement Therapy Sales by Country3.6.2 Latin America Testosterone Replacement Therapy Sales by Country3.6.3 Mexico3.6.3 Brazil3.6.3 Argentina3.7 Middle East and Africa Testosterone Replacement Therapy Market Facts & Figures by Country3.7.1 Middle East and Africa Testosterone Replacement Therapy Sales by Country3.7.2 Middle East and Africa Testosterone Replacement Therapy Sales by Country3.7.3 Turkey3.7.4 Saudi Arabia3.7.5 U.A.E 4 Global Testosterone Replacement Therapy Historic Market Analysis by Type4.1 Global Testosterone Replacement Therapy Sales Market Share by Type (2015-2020)4.2 Global Testosterone Replacement Therapy Revenue Market Share by Type (2015-2020)4.3 Global Testosterone Replacement Therapy Price Market Share by Type (2015-2020)4.4 Global Testosterone Replacement Therapy Market Share by Price Tier (2015-2020): Low-End, Mid-Range and High-End 5 Global Testosterone Replacement Therapy Historic Market Analysis by Application5.1 Global Testosterone Replacement Therapy Sales Market Share by Application (2015-2020)5.2 Global Testosterone Replacement Therapy Revenue Market Share by Application (2015-2020)5.3 Global Testosterone Replacement Therapy Price by Application (2015-2020) 6 Company Profiles and Key Figures in Testosterone Replacement Therapy Business6.1 AbbVie6.1.1 Corporation Information6.1.2 AbbVie Description, Business Overview and Total Revenue6.1.3 AbbVie Testosterone Replacement Therapy Sales, Revenue and Gross Margin (2015-2020)6.1.4 AbbVie Products Offered6.1.5 AbbVie Recent Development6.2 Endo International6.2.1 Endo International Testosterone Replacement Therapy Production Sites and Area Served6.2.2 Endo International Description, Business Overview and Total Revenue6.2.3 Endo International Testosterone Replacement Therapy Sales, Revenue and Gross Margin (2015-2020)6.2.4 Endo International Products Offered6.2.5 Endo International Recent Development6.3 Eli lilly6.3.1 Eli lilly Testosterone Replacement Therapy Production Sites and Area Served6.3.2 Eli lilly Description, Business Overview and Total Revenue6.3.3 Eli lilly Testosterone Replacement Therapy Sales, Revenue and Gross Margin (2015-2020)6.3.4 Eli lilly Products Offered6.3.5 Eli lilly Recent Development6.4 Pfizer6.4.1 Pfizer Testosterone Replacement Therapy Production Sites and Area Served6.4.2 Pfizer Description, Business Overview and Total Revenue6.4.3 Pfizer Testosterone Replacement Therapy Sales, Revenue and Gross Margin (2015-2020)6.4.4 Pfizer Products Offered6.4.5 Pfizer Recent Development6.5 Actavis (Allergan)6.5.1 Actavis (Allergan) Testosterone Replacement Therapy Production Sites and Area Served6.5.2 Actavis (Allergan) Description, Business Overview and Total Revenue6.5.3 Actavis (Allergan) Testosterone Replacement Therapy Sales, Revenue and Gross Margin (2015-2020)6.5.4 Actavis (Allergan) Products Offered6.5.5 Actavis (Allergan) Recent Development6.6 Bayer6.6.1 Bayer Testosterone Replacement Therapy Production Sites and Area Served6.6.2 Bayer Description, Business Overview and Total Revenue6.6.3 Bayer Testosterone Replacement Therapy Sales, Revenue and Gross Margin (2015-2020)6.6.4 Bayer Products Offered6.6.5 Bayer Recent Development6.7 Novartis6.6.1 Novartis Testosterone Replacement Therapy Production Sites and Area Served6.6.2 Novartis Description, Business Overview and Total Revenue6.6.3 Novartis Testosterone Replacement Therapy Sales, Revenue and Gross Margin (2015-2020)6.4.4 Novartis Products Offered6.7.5 Novartis Recent Development6.8 Teva6.8.1 Teva Testosterone Replacement Therapy Production Sites and Area Served6.8.2 Teva Description, Business Overview and Total Revenue6.8.3 Teva Testosterone Replacement Therapy Sales, Revenue and Gross Margin (2015-2020)6.8.4 Teva Products Offered6.8.5 Teva Recent Development6.9 Mylan6.9.1 Mylan Testosterone Replacement Therapy Production Sites and Area Served6.9.2 Mylan Description, Business Overview and Total Revenue6.9.3 Mylan Testosterone Replacement Therapy Sales, Revenue and Gross Margin (2015-2020)6.9.4 Mylan Products Offered6.9.5 Mylan Recent Development6.10 Upsher-Smith6.10.1 Upsher-Smith Testosterone Replacement Therapy Production Sites and Area Served6.10.2 Upsher-Smith Description, Business Overview and Total Revenue6.10.3 Upsher-Smith Testosterone Replacement Therapy Sales, Revenue and Gross Margin (2015-2020)6.10.4 Upsher-Smith Products Offered6.10.5 Upsher-Smith Recent Development6.11 Ferring Pharmaceuticals6.11.1 Ferring Pharmaceuticals Testosterone Replacement Therapy Production Sites and Area Served6.11.2 Ferring Pharmaceuticals Testosterone Replacement Therapy Description, Business Overview and Total Revenue6.11.3 Ferring Pharmaceuticals Testosterone Replacement Therapy Sales, Revenue and Gross Margin (2015-2020)6.11.4 Ferring Pharmaceuticals Products Offered6.11.5 Ferring Pharmaceuticals Recent Development6.12 Kyowa Kirin6.12.1 Kyowa Kirin Testosterone Replacement Therapy Production Sites and Area Served6.12.2 Kyowa Kirin Testosterone Replacement Therapy Description, Business Overview and Total Revenue6.12.3 Kyowa Kirin Testosterone Replacement Therapy Sales, Revenue and Gross Margin (2015-2020)6.12.4 Kyowa Kirin Products Offered6.12.5 Kyowa Kirin Recent Development6.13 Acerus Pharmaceuticals6.13.1 Acerus Pharmaceuticals Testosterone Replacement Therapy Production Sites and Area Served6.13.2 Acerus Pharmaceuticals Testosterone Replacement Therapy Description, Business Overview and Total Revenue6.13.3 Acerus Pharmaceuticals Testosterone Replacement Therapy Sales, Revenue and Gross Margin (2015-2020)6.13.4 Acerus Pharmaceuticals Products Offered6.13.5 Acerus Pharmaceuticals Recent Development 7 Testosterone Replacement Therapy Manufacturing Cost Analysis7.1 Testosterone Replacement Therapy Key Raw Materials Analysis7.1.1 Key Raw Materials7.1.2 Key Raw Materials Price Trend7.1.3 Key Suppliers of Raw Materials7.2 Proportion of Manufacturing Cost Structure7.3 Manufacturing Process Analysis of Testosterone Replacement Therapy7.4 Testosterone Replacement Therapy Industrial Chain Analysis 8 Marketing Channel, Distributors and Customers8.1 Marketing Channel8.2 Testosterone Replacement Therapy Distributors List8.3 Testosterone Replacement Therapy Customers 9 Market Dynamics 9.1 Market Trends 9.2 Opportunities and Drivers 9.3 Challenges 9.4 Porters Five Forces Analysis 10 Global Market Forecast10.1 Global Testosterone Replacement Therapy Market Estimates and Projections by Type10.1.1 Global Forecasted Sales of Testosterone Replacement Therapy by Type (2021-2026)10.1.2 Global Forecasted Revenue of Testosterone Replacement Therapy by Type (2021-2026)10.2 Testosterone Replacement Therapy Market Estimates and Projections by Application10.2.1 Global Forecasted Sales of Testosterone Replacement Therapy by Application (2021-2026)10.2.2 Global Forecasted Revenue of Testosterone Replacement Therapy by Application (2021-2026)10.3 Testosterone Replacement Therapy Market Estimates and Projections by Region10.3.1 Global Forecasted Sales of Testosterone Replacement Therapy by Region (2021-2026)10.3.2 Global Forecasted Revenue of Testosterone Replacement Therapy by Region (2021-2026)10.4 North America Testosterone Replacement Therapy Estimates and Projections (2021-2026)10.5 Europe Testosterone Replacement Therapy Estimates and Projections (2021-2026)10.6 Asia Pacific Testosterone Replacement Therapy Estimates and Projections (2021-2026)10.7 Latin America Testosterone Replacement Therapy Estimates and Projections (2021-2026)10.8 Middle East and Africa Testosterone Replacement Therapy Estimates and Projections (2021-2026) 11 Research Finding and Conclusion 12 Methodology and Data Source 12.1 Methodology/Research Approach 12.1.1 Research Programs/Design 12.1.2 Market Size Estimation 12.1.3 Market Breakdown and Data Triangulation 12.2 Data Source 12.2.1 Secondary Sources 12.2.2 Primary Sources 12.3 Author List 12.4 Disclaimer

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Testosterone Replacement Therapy Market Overview and Outlook Report by 2026 - Weekly Wall

QOL and body composition benefits seen with novel oral T treatment – Urology Times

Posted: June 13, 2020 at 10:52 am

New data from phase 3 clinical trials provide further evidence supporting the safety and effectiveness of the first-to-market oral testosterone undecanoate treatment for hypogonadism (Jatenzo), reported Stanton Honig, MD.

Honig presented results for secondary end points from 2 randomized studies comparing the lipoprotein-coated testosterone undecanoate formulation with topical testosterone treatments showing that both the oral and gel products were associated with statistically significant improvements in psychosocial well-being and bone and body composition parameters. Safety analyses showed the oral testosterone undecanoate was associated with a modest increase in blood pressure, which was slightly higher in men with hypertension at study entry than in men with normal blood pressure and that neither the oral nor gel testosterones had any significant effect on liver function test results.

This novel formulation of testosterone undecanoate is a first-in-class oral testosterone replacement that does not have liver issues, said Honig, professor of clinical urology and director, Mens Health, Yale University School of Medicine, New Haven, Connecticut.

Taken twice daily, it provides hypogonadal men with total testosterone concentrations in the mid-eugonadal range. Its safety profile is generally consistent with injectable and topical testosterone preparations, although the product labeling for oral testosterone undecanoate includes a black box warning about the potential for increased blood pressure. The data collected in the oral testosterone undecanoate studies underscore the need to check blood pressure at some point in men who are started on this therapy, especially those who are hypertensive at baseline.

The 2 trials comprised a 4-month study and a 12-month investigation. Eligibility criteria were similar in the 2 trials. Men ages 18 to 65 years (to 75 years in the 12-month study) were included if they had hypogonadism (serum testosterone <300 ng/dL on 2 morning samples approximately 7 days apart), had signs and symptoms consistent with hypogonadism, and were either naive to or underwent washout from testosterone therapy.

The 4-month study randomized 222 men 3:1 to oral testosterone undecanoate 237 mg twice daily or once-daily topical testosterone solution. A total of 325 men were randomized 1:1 to oral testosterone undecanoate 200 mg twice daily or topical testosterone gel in the 12-month trial. Dose adjustments were allowed based on serum testosterone levels.

The 4 treatment groups were similar with respect to demographics and clinical characteristics in terms of baseline age, body mass index, comorbidities (prediabetes, diabetes, and hypertension), and mean baseline testosterone levels. Time-weighted average testosterone concentration increased to reach mid-eugonadal levels in all 4 treatment groups, with values ranging from 425 ng/dL to 524 ng/dL across all 4 study groups.

Data on psychosocial well-being were collected in both trials using the Psychosexual Daily Questionnaire. Results showed statistically significant improvements from baseline to study completion in mood, sexual desire, weekly sexual activity, and sexual energy with and without a partner with both the oral and topical treatments, Honig reported.

General well-being was evaluated in the 12-month study using the 36-Item Short Form Health Survey questionnaire. In the individual domains, statistically significant improvements were achieved in both the oral testosterone undecanoate and testosterone gel group and occurred in physical functioning, physical and emotional role limitation, social functioning, and bodily pain.

Changes in body composition parameters were also investigated in the 12-month study. The results for the oral testosterone undecanoate group showed spine bone mineral density, hip bone mineral density, lean body mass, and fat mass all improved significantly from baseline at 6 months with further improvements achieved at month 12.

Both the oral testosterone undecanoate and topical testosterone treatments were associated with minimal increases in serum prostate-specific antigen. Overall, the oral and topical treatments were associated with an increase of hematocrit in approximately 5% to 6% of patients.

Importantly, there were no clinical events associated with the hematocrit increases in the oral testosterone undecanoate or the testosterone gel group, nor did any patient discontinue treatment because of elevated hematocrit, Honig said.

Changes in blood pressure were followed using ambulatory monitoring. Among men treated with oral testosterone undecanoate, mean changes in 24-hour systolic and diastolic blood pressure were approximately 5 mm Hg and 2.5 mm Hg, respectively. Comparisons between men with and without hypertension at baseline showed that the average change was slightly higher in the hypertensive group.

Honig said, It is unclear whether the blood pressure rise is just for oral testosterone undecanoate or a general class effect, as it has been seen with subcutaneous testosterone preparations as well. Most importantly, both oral testosterone undecanoate and topical gel groups showed no significant changes in liver enzyme measurements over a 12-month period.

Disclosure: Honig is a consultant to Clarus Therapeutics and Endo.

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QOL and body composition benefits seen with novel oral T treatment - Urology Times


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