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‘I Lost 130 Pounds By Eating Keto And Weight Lifting’ – Women’s Health

Posted: February 17, 2020 at 3:41 am

My name is Sandra Ross (@ketokonduct), and I am 37 years old. I live in South Jordan, Utah, and work as a personal trainer. After reaching over 300 pounds and yo-yo dieting without success, I went keto, started weight lifting, and was able to lose 130 pounds.

My struggles with my weight began when I was 9 years old. I started gaining weight, and my dad put me on my first true diet, Slim Fast. Being so young, I developed a bad relationship with food. Food was viewed as bad," and all the diets just perpetuated my issues with food and weight. This pattern continued through my life into my late 20s as I yo-yo dieted to try to find a balance. When I was tipping the scales at over 300 pounds, social anxiety started to play a huge role in my poor relationship with food. I felt uncomfortable eating in public because I worried people would judge me for whatever I put in my mouth. So, I became a recluse and didnt want to leave my house. I lost friendships because I didnt want to engage with my friends. Home was safe and where I could eat what I wanted and do what I wanted without judgement.

The doctor told me if I continued to gain like I was, I would not live past my mid 30s. My labs were not ideal and I knew it was bad, but I didnt really understand the details enough to make changes. On the way home from the doctor I stopped at Carls Jr. At that moment I realized I needed to make a change, but didnt know how to start. So I started yo-yo dieting. I went to another doctor who prescribed the weight loss drug phentermine. I took it until and I maxed out the amount you can take, and it was no longer effective. So I switched to another weight loss drug called phendimetrazine and maxed out of that as well. I felt hopeless and out of options.

I didn't feel like I was being restricted or like I was on a diet. I learned that eating low-carb and higher-fat could help me lose weight and sustain that weight loss. That finally helped me curb my cravings and kept me full for much longer periods of time than when I was eating *a lot* of carbs. I finally felt what it was like to not constantly think about food. Up to that point, I was completely obsessed with food.

Breakfast: Coffee with collagen and half and half at 7 a.m. Eggs with cheese, bacon/sausage at 9 a.m.

Lunch: I will have a salad with protein (chicken or tuna) typically at 3 p.m.

Snack: Pork rinds and egg salad or cheese.

Dinner: Spaghetti with healthy noodles or steak and some sort of veggie like loaded broccoli.

Dessert: Keto cookie or berries with cream.

Typical my week of exercise includes 5 days of weight training. I got into it because I learned that if you have more lean mass you can eat more calories, and I was *all* about that!

Change 1: Incorporating fats helped curb my appetite. Fat also helps convert your body from being a carb-burner to burning fat as fuel (aka ketosis), and this helped me feel less hungry. Lowering my carbohydrate intake also freed me from being a carb addict.

Change 2: Eating fewer carbs helped ease my joint pain. Converting to burning fat as fuel helps to decrease inflammation, which helps reduce water weight and joint pain. This helped me to be able to weight train and be more physically active.

Change 3: Weight training has helped my social anxiety *so much.* In the beginning, I was at my most vulnerable and most uncomfortable. I had to put myself out there and outside of my comfort zone to make myself better and stronger and healthier. In time, I have become much more confident. The strength and the mental acuity that I have developed with weight training has also helped me overcome my anxiety.

My weight loss journey wasnt streamlined or perfect. It takes a lot of lessons and mental changes, which take time. I had to look at food differently and correct my relationship with it. For years, food comforted me. Food can be enjoyed, but it is fuel, and Ive learned to comfort myself in other ways. To make lasting changes, it's so important to be kind to yourself and give yourself time to adjust.

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'I Lost 130 Pounds By Eating Keto And Weight Lifting' - Women's Health

Weight loss story: I had stopped meeting people because of my weight! Heres how I lost 32 kilos to gain – Times of India

Posted: February 17, 2020 at 3:41 am

Imagine not being able to fit into the clothes of your choice, owing to your rapidly growing waistline. While battling extra kilos in itself is a difficult task, it becomes even more difficult when it crushes your confidence levels. When 28-year-old Nikhil Kakkar realised that it was time to take control of his life, he decided not to look back. He managed to lose a whopping 32 kilos. Here is how he did it:Name: Nikhil KakkarOccupation: Self-employedAge: 28 yearsHeight: 6 feet 3 inchesHighest weight recorded: 105 kgs

Weight lost: 32 kgs

Duration it took me to lose weight: 9 months The turning point: When you are overweight, there are a lot of things that irritate you. From not being able to wear the clothes of my choice to feeling extremely underconfident, being overweight had begun to dominate the narrative of my life. I knew that I had to do something before it was too late as my growing weight had started to really affect the quality of my life. From the day I decided to lose weight, I have never really looked back.

My breakfast: 4 boiled eggs and a cup of coffeeMy lunch: 100 grams of paneer and 100 grams of curd

My dinner: A bowl of dal with 50 grams of brown rice

Pre-workout meal: 1 cup of black coffee

Post-workout meal: 1 scoop of whey protein

I indulge in: I do not believe in the concept of cheat days. As a result, I did not have any cheat day during my entire weight loss journey.

My workout: I equally balance weight training and cardio sessions

Low-calorie recipes I swear by: I vouch on scrambled eggs, omelette and a portion of salad

Fitness secrets I unveiled: I have realised the importance of calorie deficit when you are aiming to lose weight. You need to strictly count your maintenance calories and eat less than that to lose weight.

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Weight loss story: I had stopped meeting people because of my weight! Heres how I lost 32 kilos to gain - Times of India

Insufficient evidence backing herbal medicines for weight loss – News – The University of Sydney

Posted: February 17, 2020 at 3:41 am

The most recent data on the use of weight loss supplements, from a US study, showed that among people trying to lose weight 16 percent (12 percent of men and 19 percent of women) reported past-year use.

Herbal medicines, or herbal supplements as they are commonly known, are products containing a plant or combinations of plants as the active ingredient. They come in various forms including pills, powders or liquids.

Common herbal supplements used for weight loss include green tea, garcinia cambogia, white kidney bean and African mango.

The authors write that between 1996 and 2006, 1000 dietary supplements for weight loss were listed on the Australian Register of Therapeutic Goods without evaluation of efficacy.

These substances can be sold and marketed to the public with sponsors (those who import, export or manufacture goods) only required to hold, but not necessarily produce, evidence substantiating their claims. The authors note that only 20 percent of new listings are audited annually to ensure they meet this requirement.

The growth in the industry and popularity of these products highlights the importance of conducting more robust studies on the effectiveness and safety of these supplements for weight loss, said Dr Fuller.

The review excluded studies where the herbal medicine did not include the whole plant, was comprised of plant oils or combined with other dietary supplements such as fibres and proteins. This analysis will be reported in a future paper.

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Insufficient evidence backing herbal medicines for weight loss - News - The University of Sydney

What is no-white diet for weight loss? Does it really work? – Times of India

Posted: February 17, 2020 at 3:41 am

No-white diet, as the name suggests is the diet that eliminates foods with white flour, starch and sugar. These foods are highly processed, contain a high amount of starch, carbohydrates, have a high glycemic index and offer low nutritional value, all of which are not considered good for weight loss.

No-white diet is not exactly a diet but a strategy to lose weight easily and effectively. If you are someone who is confused between the rigid diets, you can follow this simplified approach to lose weight and improve your eating habits. Following this diet can also help stabilize your blood sugar levels.

Why should you avoid white foods?

Foods with white processed ingredients contain bad carbs and lack essential nutrients and fibre. These foods fail to keep you fuller for longer, which makes us consume excess calories. These foods are also not good for people with diabetes. Common examples of such foods are biscuits, cheese, sweets and aerated drinks.

What should you eat instead?

Choose healthy options like brown, oats or multigrain bread instead of white bread. Swap your white pasta with wheat or salmonella pasta. Choose whole grains over plain rice. Replace white sugar with stevia, honey, maple syrup or brown sugar.

How good is the no-white diet?

Judging the white foods based only on their colour is not a healthy idea. Some foods like milk, tofu and paneer are also white in colour but are full of nutrition and are a must have to lose weight and be healthy.

White foods one must eat

Cottage cheese, yoghurt, coconut, cauliflower, white chicken, all these foods are a great source of nutrition and make an integral part of a weight loss diet.

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What is no-white diet for weight loss? Does it really work? - Times of India

‘This Is Us’: Why Kate’s Weight Isn’t the Real Issue With Marc, According to an Expert – Showbiz Cheat Sheet

Posted: February 17, 2020 at 3:41 am

Many can relate Chrissy Metzs portrayal of Kate Pearson on NBCs This Is Us. As one of The Big Three siblings, Kates journey is a complex one. Her formative years are marred by tragedy, grief, and her potentially toxic boyfriend, Marc (Austin Abrams). Viewers know Kates weight is a heavy burden in her marriage and life, but whatever number the scale reads, Kates troubles go far beyond that, according to an expert.

[Warning: Spoilers from a recent episode of This Is Us ahead]

This Is Us star, Chrissy Metz, has been an open book in regards to her own weight and self-love journey. She even wrote extensively about the pressure to be a certain size to find success in the industry.

I think, as we evolve as human beings or in our particular life, we realize, Oh, you know, this isnt serving me anymore, she previously told The Wrap.

Or, if we, God forbid, come across medical issues or problems that, Oh, maybe I just wanna be a little more active. And some people knock the girls that lose weight and say like, Why did you guys do that? Youre selling out. And thats not necessarily true.

Metz referenced her character, Kate, saying, Oh, no, shes finally contending with the things that she was eating over. I think its more about the behavior around what youre doing, Metz said.

And it could be social media, gambling, sex, drinking, food it could be anything, fill in the blank how is my behavior around that and how do I want to change that behavior? Because its the stinking thinking of obsessing about something.

The actress said for her, she often wonders if shes eating for health or if its something bigger.

And whether I lose weight or I dont, I dont really hold on to a number. I dont think thats important, cause whos to say what? she said.

She continued: People are like, Wait, what? You got your blood work done and you have like great, perfect cholesterol? Like, it doesnt make sense. Im like, I want you to know its real, she continued. Like, contrary to popular belief or what were told about what looks healthy or what doesnt look healthy.

In an earlier interview with Yahoo, Metz revealed a panic attack put her in the hospital. It was her 30th birthday and shed just lost 100 pounds. She landed a role in American Horror Story with one caveat: don a fat suit.

I was thrilled to find out that I wasnt big enough, she said. It was a first in my life. It was liberating.

She went on to discuss the difficulties wearing the suit in her trailer saying she became stuck in the doorway.

I had to suck it in, squish it, knead it, hold the dress, and slowly pull it through until I stumbled down the stairs. I almost wish someone had been there to see because they would have been laughing their butt off, she said.

She elaborated in another interview with People, comparing the experience to real life.

I thought,What if I become that heavy and cant walk around or get stuck in the doorframe?I was like, I dont want this for me,' she said.

Kari Anderson, a Certified Eating Disorders Specialist in Scottsdale, Arizona, wrote her thoughts about Kate Pearsons story via Psychology Today, suggesting the weight isnt the real issue at all.

She noted a fan group had a lot of questions and concerns about Kates weight and decided to break down Kates journey through an eating disorder case conceptualization model, through a few categories: Vulnerabilities in Childhood, Trauma Triggers, and Current Stressors.

Anderson noted Kates connection to food is through the bond she had with Jack (Milo Ventimiglia). Those times they got ice cream made Kate feel unconditional love which, according to Anderson, is classic emotional eating.

As far as Kates relationship with Rebecca (Mandy Moore), its more complicated. Rebecca served as a protector, hoping to keep Kate from weight bias and judgment from others. But, it manifested into a thin is ideal mantra.

Rebeccas food rules for Kate and not Kevin or Randall only drove Kate to forbidden: foods, creating insecurity and body shame. This only escalated when those girls at the pool made Kate believe boys wont like fat girls. Marc will only reinforce those ideations.

On a deeper level, Anderson said Kates first diet came just before Jacks death. Subconsciously, Kate connects that loss to being thin and protects herself by keeping the weight on. Anderson calls it post-weight-loss trauma, and explained in Kates mind, bad things happened when she lost the weight. It was her survival instinct to binge eat. Add Marc, sex, and body image to this arc and the traumas will come up again.

Current stressors in Kates life include having visually-impaired baby Jack after doctors warned of complications due to weight. That aside, her marital troubles with Toby are only escalating. Kate may return to stress eating to cope.

There are conflicting reports as to whether Metz has a clause in her contract to lose weight on This Is Us. In one interview with TV Line, Metz said she did sign a contract with a weight-loss clause.

That was a win-win for me because its one thing to try to do it on your own. But as human beings, its an ego thing: Were more likely to do something for someone else, she said.

However, in another interview with People, Metz insisted there isnt an explicit notation about weight-loss or surgery of any kind. She did add theres an understanding Kate will lose [at least some] weight.

The point is, Kate may have a long road ahead of her, but Metz is happy at any size as she should be.

There are some days where Im like, Oh, Im definitely eating my feelings. And then some days Im like, Yeah, when my heart is full, Im not hungry.So I want to take care of my body and live a healthy life? Absolutely. But that doesnt mean you cant do it at an unconventional size.

She continued: Whether or not I lose weight or stay the same, its purely a choice of mine for health, Not because I think that plus size, curvy voluptuous, big bodies arent attractive because I think theyre awesome and sexy, she said in 2016, adding that shes not selling out the big girls.

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'This Is Us': Why Kate's Weight Isn't the Real Issue With Marc, According to an Expert - Showbiz Cheat Sheet

Fans are really concerned about MAFS’ Elizabeth Sobinoff’s drastic weight loss – Who

Posted: February 17, 2020 at 3:41 am

They have expressed their concern online.

Married At First Sighthave expressed their concern for Elizabeth Sobinoff's dramatic weight loss.

WATCH: Karl Stefanovic slams MAFS experts over joke about Lizzie

The 28-year-old reality-TV star posted a photo of herself enjoying a cup of tea, when fans took to social media to express their concerns.

"Way toooo thin now," one person wrote.

"You so thin!" another added.

"Are you well? another asked.

This picture of Elizabeth has fans concerned.

Instagram

Elizabeth has shed a whopping 10kg since first appearing on the show.

"I've thought that when I weighed 49kg and when I've weighed 90kg. I want women to realise that we're all so much more than a number on a scale," she revealed.

"So, yes, I've lost some weight since I was a 'huge' size 10 when I was onMAFS, but that doesn't mean I'm any 'better' now, just because I'm slimmer."

She has lost a whopping 10kg since first appearing on the show.

Instagram

However Elizabeth maintains that her drastic weight loss is the result of illness not dieting.

Speaking previously to an Australian magazine, the MAFS star said she had lost weight because of an auto-immune condition similar to lupus.

This means Lizzie needs to follow a strict eating plan and adheres to a high-carbohydrate diet.

She also says no to coffee, tea and alcohol.

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Fans are really concerned about MAFS' Elizabeth Sobinoff's drastic weight loss - Who

Weight Loss Recipe: This 10 Minute Spinach Soup Is Sure To Be A Hit With Dieters – NDTV Food

Posted: February 17, 2020 at 3:41 am

Highlights

There is something about a big bowl of hot comforting soup that makes us forget all our day's woes. Soup has been our go-to favourite in sickness and in health. There are reasons aplenty why it is such a hit with dieters. It is filling; the high-liquid content of soups imparts a sense of satiety. If you feel full, you would not give in to cravings so easily and maintain a safe distance from all things fried and fattening. You can also be super creative with your soup preparation too and make it healthier. Think herbs, spices, fresh veggies, mushrooms and greens. Unlike juicing, you do not lose a whole lot of fibre in 'souping', and fibre is a crucial component of a weight-loss diet.

(Also Read:Winter Special: A Healthy And Refreshing Spinach (Palak) Juice For Winter Detox)

One of the most preferred ingredients in a soup is spinach. Spinach is rich in fibre; it is the perfect example of a 'good carb'. It does not get digested too soon, it stays in your system for a while, giving you the feeling of fullness. Spinach is also super low in calories and replete with nutrition. Spinach is a rich source of iron, magnesium, calcium, potassium, folate and vitamin A.

(Also Read:Wondering What to Do With Left-Over Spinach? Sneak Them in These Puffy Palak Puris! (See Video)

What sets this spinach soup apart is that it is super easy to make and requires bare minimum ingredients and time to put it together. Make sure you wash spinach well beforehand.

Ingredients of Spinach Soup

Recipe of Spinach Soup:

1. In a pan, slightly saute garlic and onion in butter.

2. Add spinach and saute for a minute.

3. Add the spinach with one glass of stock, cream, salt and pepper and blend on high speed.

4. Blend for a minute, until you achieve the desired consistency. If it is too thick, add more veg stock in the blender and blend again.

5. Take the soup out of the blender, serve with a squeeze of lime and garnish with coriander leaves.

Try making this soup and let us know how you liked it in the comments section below!

About Sushmita SenguptaSharing a strong penchant for food, Sushmita loves all things good, cheesy and greasy. Her other favourite pastime activities other than discussing food includes, reading, watching movies and binge-watching TV shows.

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Weight Loss Recipe: This 10 Minute Spinach Soup Is Sure To Be A Hit With Dieters - NDTV Food

Friendships, pets, money, weight loss … what makes you feel happier? – The Sydney Morning Herald

Posted: February 17, 2020 at 3:41 am

Professor Robin Dunbar from the University of Oxford told The Guardian that at a psychological level, having friends just makes you happier. The kinds of things you do with other people are very good at triggering the endorphin system, which is part of the brains pain-management system.

Endorphins are opioids which are chemically related to morphine, and which flood our brains when we interact with others, including cuddling and stroking: It is central to the way primates in general bond in their social groups and relationships, he said.

The kinds of things you do with other people are very good at triggering the endorphin system, part of the brains pain-management system.

The 2018 annual report on adolescents by the Australian Institute of Family Studies also found that the average resilience scores were higher for adolescents who had at least one good friend than for those who did not, says one of the reports authors, Dr Constantine Gasser.

And while human relationships may be the best form of social interaction, experts say the company of animals should also not be underestimated.

Animals are a particular kind of relationship: less stressful and demanding they just like you, says Dr Janette Young, lecturer in health promotion and policy at the University of South Australia.

Theyre a social lubricant, Dr Young says. Animals facilitate connectivity between people and help break down social barriers, especially during dog walks, when people talk to the dog but are actually engaging with the person.

As for social media, it appears that its positives (fostering connections and giving voice to the disenfranchised) may be slowly being overtaken by its negatives (such as cultivating feelings of inadequacy, encouraging addiction, exacerbating cyberbullying, providing easier access to psychologically dangerous content and a decreased attention span).

Social media use has also been linked to rising levels of anxiety and depression the more people use it.

But does it actually make us unhappy? It depends on who you ask, says Nicholas Carah, the University of Queenslands Associate Professor in the School of Communication and Arts.

These platforms are not designed in the interests of users they couldnt care less about what impact they have on users wellbeing

Theres a lot of popular debate about this question. [Some argue] theres a connection between the rise of the smartphone and a bunch of [negative] changes in the lives of young people that perhaps in the long term mean we are less happy because we are less resilient.

Then [others] point to a much more nuanced story, where social media on its own doesnt make us more or less happy, rather it is the way [platforms] are used, what we use them for, he says.

Based on his own work (which focuses on how social media platforms are designed to colonise our attention in order to sell it to advertisers), Professor Carah is less forgiving: These platforms are not designed in the interests of users which means that they couldnt care less about what impact they have on users wellbeing.

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Another thing we tend to think, often incorrectly, will make us happy is losing weight. In our image-obsessed society, the idea of weight loss has become synonymous with wellbeing, yet experts say there is little to no evidence that losing a small amount of weight such as 5kg will actually increase our happiness.

While there are no studies that directly measure happiness and weight loss, there are reviews that look at losing weight and quality of life, says Clare Collins, Professor in nutrition and dietetics at the University of Newcastle.

For example, research looking at overweight and obese adults has found that while weight loss is associated with a better physical quality of life, there was no difference in the mental quality of life.

Professor Collins says that weight loss only discernibly improves a sense of wellbeing when it is huge: For example, studies show that people whove had bariatric surgery see a much bigger improvement in their quality of life but there doesnt seem to be much evidence directly for evidence for small weight loss.

There is little to no evidence that losing a small amount of weight such as 5kg will actually increase our happiness.

What does seem to make us happier is eating better. A 2016 HILDA survey that looked at the food diaries of 12,000 Australians in 2007, 2009 and 2013 found that over that time period, increased fruit and vegetable consumption increased happiness, life satisfaction and wellbeing.

What this suggests is that losing weight may be too hard a thing to pin your happiness on, Professor Collins says. You will get more return on your investment improving your vegetable and fruit intake than just wanting to lose a bit of weight.

Humans have a peculiar propensity to wrongly predict what will make them happiest.

Despite research showing that materialists tend to be less happy and satisfied with their lives, our consumer society continually strives to reinforce that happiness is rooted in purchasing bigger, better things which requires earning more money.

We know that up to a point, earning money does make you happier before it tapers off and even recedes, says Australian social psychologist Dr Brock Bastian, author of The Other Side of Happiness. Additional income doesnt really add much to happiness.

That said, to judge how much money we need to be happy can also be subjective to each individual: It's the amount that lets you afford things you feel are necessary for your life," says Dr Bastian.

Yet population studies show that when it comes to money, a significant indicator of happiness is what you choose to spend it on, rather than how much you earn.

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We know that experiences rather than things are more important for happiness, and using money to access enjoyable, valuable experiences is when having money becomes important to happiness, he says.

This is also echoed in other research, which found that despite people initially predicting experiences to be lower value for money than things, most changed their minds after the fact and realised that doing things rather than acquiring them actually made them happier.

Caroline is a contributing writer to The Age and Sydney Morning Herald

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Friendships, pets, money, weight loss ... what makes you feel happier? - The Sydney Morning Herald

Beverages to avoid if youre trying to lose weight in a better & more efficient way – Republic World – Republic World

Posted: February 17, 2020 at 3:40 am

Weight loss is one of the toughest tasks for an individual as cutting down on certain foods and beverages can be a challenging chore. The more you try to follow a diet, the more you crave for your favourite food. However, when on a diet it is important to know what to have and what to avoid. Here is a compilation of a few beverages you should avoid when trying to lose weight.

According to Natalie Rizzo (New York dietician),soda is loaded with unnecessary sugar and calories that slow down the process of weight loss. These drinks are not filling too, that is why it is better to avoid these during weight loss journey.

From diet soda to diet iced tea, these drinks instead of helping inweight loss, enhance your calorie intake which is bad for weight loss. According to Rizzo, instead of these, you can drink freshly prepared fruit juices without sugar.

Also Read|'Reverse Microwave' unveiled that chills foods and beverages in minutes

Sweetened tea can rack up about 100 calories and more than 20 grams of sugar per drink which is not a good thing when you are trying to lose weight. Instead of this, you can have green tea or chamomile tea or any kind of unsweetened tea.

Also Read|Hyderabad: Edible cups launched for serving a variety of beverages

According to the dietician, when you are out and about to have coffee, try to avoid the tempting options like vanilla lattes or caramel macchiato. She said that the syrup that gives these drinks flavour has more sugar and calories than desserts. Instead of this, you can opt for a regular coffee with some milk.

Also Read|Winter soups: Hot tasty beverages to try out to stay healthy this cold season

Alcohol consumption can hinder your weight loss efforts on a very large scale. Fruity cocktails like Daiquiris, Pina Coladas and Mojitos have a huge amount of sugar that increases the calorie intake and hinders your weight loss.

Also Read|Mocktails: Best home made recipes for the refreshing beverages

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Beverages to avoid if youre trying to lose weight in a better & more efficient way - Republic World - Republic World

MS: Dietary interventions may calm down the immune system – Medical News Today

Posted: February 15, 2020 at 9:46 pm

A study in mice has shown that a change in diet may slow diseases that involve the activation of the immune system, such as multiple sclerosis (MS). Could the findings lead to improved treatments in humans?

In the United States, nearly 1 million people over the age of 18 are living with a diagnosis of MS, according to estimates.

MS is the most common of the inflammatory disorders with an autoimmune component, which refers to the immune system attacking and damaging healthy tissue.

In MS, the immune system attacks the myelin sheaths that protect the nerve cells in the brain and spinal cord, disrupting nerves messages to and from the brain.

The result can involve muscle weakness, numbness, trouble with balance and coordination, and cognitive decline, all of which get worse over time.

Doctors most frequently diagnose MS in young adults, although the diagnosis can be made at any age.

At present, no medical treatment can prevent or slow MS without greatly increasing the risk of infection or cancer. But what if dietary changes could delay the diseases onset and progression in high risk individuals?

Researchers have recently explored the role of methionine, an amino acid, in the overactive inflammatory response of conditions such as MS.

The teams results now appear in the journal Cell Metabolism.

While methionine is essential to a healthy immune system, it has an adverse effect on people at risk of autoimmune disease.

Russell Jones, Ph.D., of the Van Andel Institute, in Grand Rapids, Michigan, is the studys senior author. He comments on the findings, explaining:

Our results suggest [that] for people predisposed to inflammatory and autoimmune disorders like multiple sclerosis, reducing methionine intake can actually dampen the immune cells that cause disease, leading to better outcomes.

Many types of cell throughout the body produce methionine, a building block of protein and a form of fuel.

Defensive immune cells that respond to threats called T cells do not produce their own methionine and instead rely on dietary sources.

Certain animal products, such as meat and eggs, have especially high amounts of methionine.

One of the ways that the body defends itself against threats such as pathogens, or germs, is by flooding the affected area with T cells.

The researchers found that ingested methionine added fuel to this process by helping the T cells replicate and branch into specialized subtypes quicker.

However, once boosted by methionine, some of these reprogrammed T cells caused inflammation or swelling.

This is usually a healthy immune response, but if the swelling persists, it can cause damage such as that which characterizes MS.

The scientists found that dramatically lowering the amount of methionine in the diet of mice with induced MS changed the reprogramming of their T cells and limited the cells ability to cause swelling in the brain and spinal cord.

This, in turn, slowed the diseases progression.

These findings provide further basis for dietary interventions as future treatments for these disorders, Jones notes.

By restricting methionine in the diet, youre essentially removing the fuel for this overactive inflammatory response without compromising the rest of the immune system. Russell Jones, Ph.D.

However, before dietary guidelines can be established, researchers must prove that humans also experience these effects.

At present, there is no comprehensive understanding of the cause of MS, although genes related to the immune system play a role, as do environmental and metabolic factors, such as obesity.

The fact that metabolic factors like obesity increase the risk of developing multiple sclerosis makes the idea of dietary intervention to calm down the immune system particularly appealing, says co-author Catherine Larochelle, Ph.D., of the University of Montreal, in Canada.

The researchers will also investigate the possibility of creating new medications to target methionine metabolism.

The present study is only the latest to explore the role of dietary methionine limitation in disease treatment.

In 2019, a study from the Locasale Lab, at Duke University, in Durham, NC, showed that the cancer-fighting effects of chemotherapy and radiation could be improved by reducing methionine intake.

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MS: Dietary interventions may calm down the immune system - Medical News Today


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