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Popular Foods That Lead to Body Fat, Say Experts | Eat This Not That – Eat This, Not That

Posted: July 16, 2021 at 1:47 am

Trying to figure out which foods quickly transform into body fat could confuse anyone, especially if you're just starting to learn healthy eating habits. Luckily, we consulted a handful of dietitians and experts who shared what common foods have the potential to pack on the pounds. If you want to slim down and can't figure out why your diet hasn't worked, make sure none of these popular foods slow down your progress and lead to body fat.

Read on to learn which popular foods sneakily lead to extra body fat and for maximum results, make sure to check out 40 Best-Ever Fat-Burning Foods to supercharge any of your weight loss goals.

You might never guess, but your favorite applesauce unknowingly added a bit of fat into your meal plan.

"Foods sweetened with artificial sweeteners likelight applesaucetend to make people gain fat weight around the belly," says Heidi Moretti, RD. "Because sweet foods are very calorically dense and tasty, people tend to overeat them. In terms of metabolism, sugar is very harmful to have in the blood, so the body turns it into a less harmful substance quickly, which happens to be fat in the blood. This fat then is stored if it isn't used immediately as energy."

"Sadly, artificial sweeteners aren't a free pass either," Moretti continues. "Foods sweetened with sucralose may increase glucose entry into the cell, which can lead to packing on extra body fat as new research shows."

If you noticed some extra weight building around your stomach, you might have alcohol to blame.

"Excess alcohol use is widely associated with increased adiposity, which is why we often hear the term 'beer belly,'" says Dr. Uma Naidoo, nutritional psychiatrist. "Chronic alcohol consumption is shown to disrupt the gut microbiome and can lead to leaky gut syndrome, which leads to inflammation and can increase body fat. Similarly, alcohol is high in 'empty' calories, meaning it does not contain nutrients, and can influence unhealthy food choices after consumption, which can overall increase risk of obesity."

When you want to indulge in an adult beverage but avoid the consequences that come with alcohol, check out 15 Best Non-Alcoholic Drinks That Are Actually Worth Buying and find your next favorite mocktail or non-alcoholic spirit.

When it comes to managing body fat, keep an eye out for white bread.

"When wheat is refined to make this white flour that constitutes many processed foods, it is stripped of not only most of its nutrients, but also its fiber and protein, leaving a product that is essentially all sugar and high on the glycemic index," says Dr. Naidoo.

"When consumed, they are digested similarly to added sugars as discussed above," says Dr. Naidoo. "They contribute to increased blood sugar levels and metabolic disease consistent with insulin and leptin resistance, and increased energy storage in fat cells, or overall increased body fat. Due to the simplicity of these foods and their lack of fat and protein to slow digestion, high glycemic processed foods are notably unsatisfying and associated with excess calorie intake."

Instead, focus on consuming more of these 9 Best Complex Carbs for Weight Loss.

"This common snack food often leads to increased body fat, especially if indulged in too frequently," says Matthew Olesiak, MD. "In fact, one study found potato chips to be the food likely to lead to the most weight gain over a 4-year periodcompared to potatoes, sugar-sweetened beverages, processed and unprocessed meats."

"Potato chips are loaded with fat, refined carbs, and salt," Dr. Olesiak continues. "All three work together to make them addictive, a big reason why you 'can't eat just one.' This often leads to overeating a high-fat, high-calorie food with resulting weight gain."

"In addition, the refined carbs in potato chips are particularly bad for the waistline, as they are often stored as fat," says Dr. Olesiak. "When you eat refined carbs stripped of digestion-slowing fiber, they are broken down very quickly with the resulting glucose dumped into your bloodstream all at once. This causes a rapid rise in blood glucose and triggers a release of the fat-storage hormone insulin. Some of this glucose is used immediately for energy. The rest is converted into fat for long-term storage. So, if you eat potato chips and other refined carbs, most of the calories will be stored as fat."

If you love a good chip and don't want to give up the treat, don't fret! Take a look at the 11 Best Brand Name Chips for Weight Loss and get your snack on.

Few foods can match the sugary, fried goodness found in a doughnut. While this morning delight tastes great, too many doughnuts can lead to excess body fat.

"Doughnuts are loaded with sugar and refined carbs that cause a rapid rise in blood sugar levels that temporarily satisfies your hunger," says Dr. Olesiak. "Meanwhile, the pancreas releases an equally large secretion of insulin to quickly clear excess glucose from your bloodstream and move it into your cells."

"As the glucose enters your cells, you experience a surge of energy that lasts for only about 20 minutes," Dr. Olesiak continues. "But as the glucose in your bloodstream rapidly declines, so does your energy. This is why you often become tired after eating refined carbs and foods with added sugar. You'll also feel hungry again and reach for another doughnutor two or three. This can easily add up to 1,000 [or more] empty calories that lead to an increase in body fat. Plus, most of the calories in refined foods are stored as fat."

If you thought you could get away with using margarine in place of butter to keep extra fat from building up, guess again.

"We went from seeing margarine, especially low-fat margarine, as the food the doctor ordered to reviling its trans fats and its nature as a contrived, ultra-processed food associated with fatness and chronic disease and accepting the once 'evil' butter as a natural spread of choice," says Dr. Julie Miller Jones, LN, CNS.

"The low-fat fad resulted in the development of many products with no fat, which caused many consumers to believe they could eat unlimited amountsafter all the label said 'free.' This misperception meant that some cases consumed large amounts of the no-fat cookie or cake and did not lose weight, but rather gained it."

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Intermittent Fasting and Weight Loss | Is Intermittent Fasting Effective? – runnersworld.com

Posted: July 3, 2021 at 1:51 am

Intermittent fasting, which restricts your snacks and meals to a certain timeframe during the day, may have some benefits depending on your goals. But when it comes to weight lossif thats your goal!a new study in the journal Science Translational Medicine suggests the approach isnt more effective than simply reducing the total daily calories you eat, and eating them at unspecified times.

In fact, intermittent fasting may even be detrimental to muscle mass, according to lead researcher James Betts, Ph.D., co-director at the Center for Nutrition, Exercise, and Metabolism at the University of Bath in the U.K.

Researchers recruited 36 participants and assigned each to one of three groups for three weeks. The first group didnt intermittently fast at all and just reduced their daily calories by 25 percent. The other two groups fasted on alternate days, with one group following a fast day by eating 50 percent more than usual and the other group eating 100 percent more.

At the studys conclusion three weeks later, the last group showed no weight loss, while the first group and the 50 percent group each lost about the same amount of weight but with significant differences, Betts told Runners World. Those who fasted and then ate 50 percent more lost much more muscle mass than the non-fasting group.

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Because of this, anyone who wants to do intermittent fasting needs to keep in mind that they may need to do more physical activity in order to maintain muscle mass, he said.

Another factor to consider here is quality of foods, Kristin Gillespie, M.S., R.D., a dietitian and certified nutrition support coach, told Runners World.

You may help stimulate weight loss if youre consuming fewer calories simply because youre reducing the number of hours that youre eating, she said. However, it is certainly possible to offset this calorie deficit if youre consuming calorie-dense foods during your eating window.

The premise of intermittent fasting is that youre meant to be eating nutrient-dense, healthy foods in relatively normal amounts during the eating timeframe, she added. When you stray away from that with a junk food binge, its doubtful youll see benefits just from going without eating for 12 hours or more.

Another caveat is that the study did include men and women, but didnt differentiate those results. Gillespie said that women generally dont do as well with this strategy because they tend to be more adaptable to periods of fasting and energy conservation, so it would be interesting to see a study focusing on only women.

Finally, theres the size of the study36 participants is considered a modest sampleand the fact that all of the participants were technically classified as lean with a body mass index in the low 20s. However, Betts said that the results should not dissuade anyone from trying the tactic, especially if theyre willing to play around with it.

I do think that different fasting strategies may have different effects, he said. For example, whether to vary fasting times each day, how you re-feed, how long you fast, and so on.

The bottom line? Eat in a way that works best for you and lines up with your own nutrition and training goals. And, as always, consulting with a sports dietitian or other medical expert is the best way to personalize your diet for best results.

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Intermittent Fasting and Weight Loss | Is Intermittent Fasting Effective? - runnersworld.com

The COVID weight gain: Professional tips for losing the pandemic pounds – MLive.com

Posted: July 3, 2021 at 1:51 am

About 42% of Americans reported unwanted weight gain during the coronavirus pandemic, packing on an extra 29 pounds on average, according to survey results from the American Psychological Association.

Changes in daily routine, combined with the added stress of navigating a global health emergency, caused many adults to fall away from their healthy eating and fitness habits, and turn toward less-desirable comfort foods.

Dr. Geri Williams, supervising doctor for Ideal You Health Centers, called it the perfect storm for weight gain.

When we feel stressed, we naturally create higher levels of cortisol and when its elevated, our body is primed for movement, our blood sugar goes up and if were not running it off it stores as fat, she said. So stress alone can make us fatter.

Another thing we do is we get rid of stress by eating ... so stress from changes in lifestyle and all the unknowables created the perfect storm and we made food choices that were not heathy.

With the help of widely available vaccines, COVID-19 cases counts are on the decline and the economy -- along with daily life -- is regaining a sense of normalcy. As a result, many are starting their efforts to regain old healthy habits or begin new ones.

Williams noted a handful of strategies that can help you not just reach your goals, but maintain the lifestyle choices to keep the positive gains. They include:

Another important recommendation is to avoid eating after dark. Williams said the bodys internal clock is typically directed by daylight, meaning during the day the body is designed to look for, eat and digest food and to move around.

Meanwhile, at night, the body undergoes a hormone shift and prepares for rest and repair.

Were hungry and were eating at a time when our body isnt designed to be digesting, Williams said. Food regularly consumed after sunset is generally stored as fat. Simply changing that habit could have a huge impact on people, and that includes alcohol too.

Adding exercise to your daily routine can be beneficial in several ways, including improved strength and circulation. Its valuable for improving your overall health, but Williams noted, When it comes to weight loss, it doesnt tend to cause scale movement as much as the focus on food does.

That notion was echoed by Carrie Holland, a family physician and professor at Michigan State University, who also works as a health and life coach through her business, My Why Fitness.

Exercise and nutrition are both important but for totally different reasons, Holland said. My philosophy is dont use exercise for weight loss; use it for mental health benefits.

The nutrition piece, she said, is the hardest part to implement. Unhealthy eating and drinking can be a coping mechanism for more challenging issues to work through like the anxiety, fear, anger and disappointment that many have felt throughout the pandemic.

But it will also make the biggest difference, Holland said. How do you stop over-eating? .... These habits we developed are now autopilot and to undo it, you have to wake up that part of your brain and pay attention to what youre doing and why. When you reach into the pantry for a bag of chips, ask yourself Why am I doing this? Am I really hungry or is it out of habit?

A lot of Hollands work with her clients in recent months has been not just discussing what are better foods to buy at the grocery store, but discussing the link between mental and physical health.

A lot of diets and exercise plans focus on action -- do this and youll lose weight, she said. What I spend time working on is the thoughts and feelings. It all starts with our brains and if youre not thinking and feeling the right way, it doesnt matter if youre doing the right things, it wont happen.

Some of Hollands tips for developing healthier habits include:

While conditions during the pandemic created opportunity for weight gain, obesity isnt a new challenge for Michigan. In 2015, about 31% of adults in Michigan were obese and 35% were overweight.

The state ranked 32nd in obesity in 2018, reporting slightly higher rates than the national average, according to a federal health survey.

Read more on MLive:

5 things to know about Michigans COVID vaccine lottery

Michigan coronavirus data for Friday, July 2: Case numbers, positivity rate tick up

10 beaches across Michigan closed, under advisories going into holiday weekend

Delta variant update: Virus spread prompts new mask mandates, other restrictions around the world

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The COVID weight gain: Professional tips for losing the pandemic pounds - MLive.com

3 Reasons You’re Not Losing Weight On Intermittent Fasting – msnNOW

Posted: July 3, 2021 at 1:51 am

JGI/Jamie Grill - Getty Images Intermittent fasting is a trendy way to lose weightif done properly. These three mistakes explain why you are still fasting but not losing weight.

People do intermittent fastingnot eating for set periods of timefor many reasons. Some say they do it because they're aiming for better focus, others are pushing to better their health by reducing inflammation or improving lipid levels. Yet others do it because celebrities like Terry Crews, A-Rod, Hugh Jackman and Chris Hemsworth do it. But probably the biggest reason people turn to intermittent fasting is because they're looking to lose weight.

The practice doesn't guarantee you'll drop pounds, but many people do, largely because restricting eating to certain windows of time also tends to reduce the calories people eat.

As a refresher, there are different ways to fast, but people generally follow three common schedules: alternate-day fasting, whole-day fasting, or time-restricted fasting. Melanie Boehmer, R.D. at Lenox Hill Hospital, recommends starting with time-restricted fasting. One popular way to do this is eating only during an 8-hour window, a format known as the 16:8 format (16 hours of fasting, 8 hours available for eating).

Sometimes you're doing an intermittent fasting plan to lose weight and the scale's just not moving. If this sounds like you, it's a good time to analyze your strategy. These common reasons may explain why you're not losing weight on intermittent fasting.

Restricting the time you get to eat doesn't always cut back calories as much as you might think, if you over-consume during your eating window.

What's over-consuming? Do a reality check on how many calories your body needs to maintain its current weight. This can be done using a formula or the body weight planner by the National Institute of Health.

Gallery: The most nutritious plant-based proteins, according to dietitians (INSIDER)

Track everything you eat in a given week using FitDay.com, Lose It!, or MyFitnessPal, and see if you're eating more calories than your body needs, even though you're restricting the timing of those calories. If you are, you know what to do.

If you're not losing weightdespite staying within your calorie needsthen it's time to look at serving sizes. It's common to miscalculate how much you're actually eating. This is particularly true with calorie-dense foods such as cheese.

For example, a one-ounce serving of full fat cheese equals about four cubes of dice. Use a food scaleor eyeball portions with this tutorialto more accurately calculate food intake. And keep in mind that you don't have to eat skimpy looking meals. Beef up a sandwich with crispy lettuce and a bunch of tomatoes. Add broccoli to your pasta to fill your bowl and look satisfying.

If you've hit a weight loss plateau after losing a few pounds, says Melanie Boehmer, R.D. of Lenox Hill Hospital in New York City, you may be eating too few calories.

That's because our bodies adjust to whatever we throw at them, she says.

"If, on average, youre only taking in 1200 calories, which is something none of us should be doing on a regular basis, your body is going to learn to function on 1200 calories," she says.

Reduce calories slowly and aim for more moderate weight loss, says Boehmer. She advises cutting enough calories to lose about a pound a week.

"When we talk about losing weight, the goal is always to lose as much weight eating the most that you can so you dont create that metabolic inhibitor," she says.

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Losing Weight By Changing Your Relationship With Food. | Scoop News – Scoop.co.nz

Posted: July 3, 2021 at 1:51 am

Friday, 2 July 2021, 9:09 amPress Release: Weightless

Food is important. It is a necessity for all of us. Itprovides us with energy to go about our day, supports ourimmune system to keep us healthy, regulates our hormones tokeep us happy and provides everything we need to heal andkeep our bones strong. Objectively, it is easy to understandthe vital role it plays in our lives. We are biologicallywired to enjoy food in order to sustain a healthy lifestyle- the consequences of chronic undereating are just asserious as overeating.

Modern day conveniences havemade food highly accessible. It is now easier than ever toindulge in foods from different cultures and convenientsources such as fast-food restaurants. The world has becomea literal smorgasbord of delicious options.

Readyaccess to convenience foods have however had a drasticeffect on lifestyle. Many of us are more sedentary thanprevious generations. This has resulted in many peoplegaining excess weight. Excess weight affects not only ourphysical health, but mental health too.

We may try tolose weight to improve our lifestyle, but if we are notcareful, we can end up vilifying food along theway.

At the end of the day food is ALWAYS going to bepart of life. As such it is important that we develop apositive relationship with it. If we develop badrelationships with food through dieting, we place ourselvesin a position to have to continually fight it. This canimpact our mental health. A good relationship with food isnot just about diet quality, the types of food you eat, oreating protocols you have chosen to implement, but ratherhow and why you choose the foods that you eat. If you canimprove your relationship with food, eating will become amore enjoyable and stress-free behaviour.

Food shouldbe an enjoyable part of life, even when losingweight.

There are a few behaviours that we need to beaware of that can be indicative of a bad relationship withfood. You might feel guilty about eating and you avoid orrestrict foods that you have deemed bad. People maydevelop a list of rules that isolate allowed foodswhich can make eating at social events stressful and asource of great anxiety. Yo-yo dieting and bouncing betweenrestricting and binging, while being drawn towards fad dietsor reliance on calorie counting apps are all signs of a badrelationship forming with food.

By building a healthyrelationship with food you can experience food freedomwhile reducing weight to a healthy level. Developing apositive relationship with food isnt an overnight fix, ittakes time and patience. Here are some steps you can take toimprove your relationship with food.

Humans arethe only creatures that dont eat food purely forsurvival, we eat to celebrate, for enjoyment and culturalreasons. However, this often means food becomes entangledwith emotional responses. We eat when were happy, we eatwhen were sad. Our reliance on food to curb emotionalresponses is further muddied by the fact that many of us areconditioned from childhood to eat everything on ourplate. Overtime, these factors disconnect us with ourability to autoregulate our hunger. We eat when we think weshould eat, rather than taking a few moments to considerwhether or not we are actually hungry. We are also moreinclined to eat everything we have served ourselves, ratherthan stopping eating once we aresatiated.

Spend some time learning tofeel your hunger levels before eating, and whilsteating take note at what point you are actuallyfull.

Modern life is full ofdistractions. When was the last time you ate withoutwatching TV or looking at your phone? These distractions doexactly that, distract us from our natural hunger andsatiety signals. Mindful eating involves removingdistractions and being present in the moment whilst eating.Take the time to focus on tasting your food, taking note ofthe texture as you chew and how the experience makes youfeel. Be present in the moment. Consciously question howfood is affecting your appetite, is the food the solution tothe reason you chose to eat? Does eating bring you joy,guilt, or something else? By staying in the moment andconsciously evaluating the experience, not only will youform a healthier connection with the reasons behind yourfood choices, but youll also be more conscious of satietycues.

When you createrules around when you can and cant eat you are likely toexperience feelings of deprivation, further fuelling a fearof food. Having a healthy relationship with food meansallowing yourself unconditional permission toeat.

Overeating at lunch or indulgingin a few snacks doesnt mean you should deprive yourselfwhen youre hungry later. This behaviour reinforces thenotion that food is bad. Eating when youre hungry andmindful eating are skills that develop over time. Try not topunish yourself if you feel you may have taken a meal toofar. Be kind to yourself.

Some foods are morenutritious than others. Some are more nutrient dense, andsome are more calorie dense. None of them should beconsidered bad. Labelling them as good orbad gives them an undeserved power over your emotionalwellbeing. Just as the grass is always greener on the otherside of the fence, the foods that you cant have mayappear more tempting. No one single food will affect youroverall health. When we eventually break our self-imposedrestrictions we are more likely to overindulge as aconsequence and feel as if we should make the most ofit!

By allowing yourself to consumeforbidden foods in moderation rather than restrictingthem, you are far more likely to regulate your intake as youknow that they are alwaysavailable.

We understand thatyour relationship with food is a complex issue with manynuances that cant always be solved on your own. It can bea challenge to overcome lifelong habits and detangle youremotional relationship with food without professionalguidance. Weightlessis a team of experienced dietitians, nurses, psychologistsand gastroenterologists who take a holistic approach toweight loss, helping you lose weight and keep it off. Weunderstand that everyones reason for coming to us isunique, and we provide services that are tailored to eachindividual to help them reach a healthy, lifelong,sustainable transformation.

If yourelooking to build a strong, healthy relationship with yourfood, our first piece of advice is to be kind to yourself.Give yourself time to work towards goals that will make youhappy and take pride in the small steps that lead you onyour journey to health. To find out about all of theservices our expert team of health professionals have tooffer, contact Weightlesstoday!

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Weight loss: Michael Mosley shares key advice on how to feel more satisfied after meals – Daily Express

Posted: July 3, 2021 at 1:51 am

Dr Michael Mosley has appeared on several television shows throughout his career, offering weight loss tips and tricks. Although not a fast process, there are ways in which you can help the body lose weight and according to Dr Mosley, this is to eat foods high in protein.

This is because foods high in protein often keep you fuller for longer, reducing the need for endless snacking throughout the day.

Less snacking means slimmers will eat fewer calories, helping to create a bigger calorie deficit.

On the topic, Dr Mosley explained: It is well known that moderately increasing the amount of protein in your diet can help you feel more satisfied after meals.

What is less well known, though, is that the time of day that you eat protein also matters.

READ MORE:Michael Mosley shares best way to prevent hunger when on a diet

The expert added: Eating protein at the first meal of the day helps you to feel fuller for longer because after a protein meal, levels of a chemical called tyrosine, a building-block for dopamine, rise inside the brain.

This does not, of course, mean that you have to eat breakfast early in the day.

For many, a midday breakfast helps to extend the period of non-eating and so draws down the full benefits of fasting.

Eating a higher-protein meal can also help to keep sugar cravings away, which can help slimmers lead a healthier lifestyle.

Dr Mosley recommends keeping away from foods high in sugar as well as junk foods.

This is because they contain little to no nutritional value, making you feel hungrier and wanting more.

He explained: If you want to feel fuller for longer, keep away from it. When youre out and about, bring a packed lunch.

If you keep a stock of high-calorie snacks in the house for children, keep it locked up and away from the kitchen.

To feel fuller for longer, take a few simple steps, choose more of the right foods, especially good fats and fibre and avoid the wrong foods, eat protein and eat it early.

Like happiness, fullness really is a gut feeling.

Drinking plenty of water throughout the day will also keep you hydrated and feeling full.

Dr Mosley said: When youre not getting enough water, youll be sluggish, lethargic, and most likely mistake thirst for hungermake sure you stay hydrated.

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Weight loss: Michael Mosley shares key advice on how to feel more satisfied after meals - Daily Express

Raven-Symone Says Wife Miranda Inspired Her to Lose Weight: I Want to Be There for Her – Us Weekly

Posted: July 3, 2021 at 1:51 am

Healthy wife, happy life! Raven-Symon opened up about her new, healthy lifestyle explaining that it was very much inspired by her wife, Miranda Pearman-Maday.

This was because we want to have a life together, the Ravens Home star, 35, told E! News on Thursday, July 1. She doesnt want to take me to an early grave and I want to make sure I am there for her in the best health possible.

The Cheetah Girls actress shared that shed decided to make some changes after receiving horrendous numbers at a doctors appointment. She first opened up about her weight loss in a May Instagram Live, revealing while in the car with Pearman-Maday, 32, that shed lost 28 pounds.

Youre incredible honey. Youre doing so good,the social media manager said in the clip.

Later, Raven talked about her health journey during a June appearance on Good Morning America, sharing that shes trying to be low-carb as much as [she can] be, exercising minimally and having a minimumof a 14-hour fastbetween dinner and breakfast. She also makes sure to listen to her body and carefully educate herself about any fasting she participates in.

The Thats So Raven alum noted that her recent weight loss isnt about achieving a certain look. Instead, she simply wants to be as healthy as can be. She also shared that what works for her wont work for everyone she speaks only for herself.

Every time I lost weight in the past it was about size, the Some Call It Magic singer said. [This time] I want tomake sure that my body is healthyand prepared to deal with old age.

The Georgia native married Pearman-Maday in a secret ceremony on June 16, 2020.

I got married to a woman who understands me from trigger to joy, from breakfast to midnight snack, from stage to home, she wrote via Instagram a couple days later to announce the happy news. I love you Mrs. Pearman-Maday! Lets tear this world a new ahole!!!

Last month, Raven shared a lengthy Instagram post to wish her wife a happy first anniversary.

365 days ago we decided to stand with each other for the rest of our years on this planet. We promised that we would have each other backs, hold each others hearts in our hands and care for them like no one else has, she wrote in part. You have done something to me that I thought wasnt possible. Youve made me smile. Not the one where I know people are watching or because Im a girl and I need to. No babe the smile comes when my hurt brain tries to take over and then I see your face. A smile that reminds me everything is gonna be OK now.

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Raven-Symone Says Wife Miranda Inspired Her to Lose Weight: I Want to Be There for Her - Us Weekly

Testosterone Replacement Therapy Market Segmentation, Analysis by Recent Trends, Development by Regions to 2028 AbbVie, Endo International, Eli lilly,…

Posted: July 3, 2021 at 1:51 am

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Student Blog: My Vocal Journey Through Testosterone and 6 Things Theatre Needs to do for Trans Voices – Broadway World

Posted: July 3, 2021 at 1:51 am

Photo taken by Karin McKenna

What are you willing to sacrifice for happiness? For me, it was my voice.

As a performer, my voice was one of the biggest obstacles in my coming out. In the theatres where I worked back home, I was known for my voice; specifically, how high it could go. I played Marian in The Music Man, Rosa Bud in The Mystery of Edwin Drood, and whenever I was in the ensemble, the music director would add in an extra high note at the end of songs just for me. I had put so much of my value and identity into my voice that the thought of it changing was absolutely terrifying. But I couldn't keep pretending to be someone that I wasn't. During one voice lesson, my teacher communicated to me that if I kept up my current eating habits (or lack thereof), I could do permanent damage to my voice. My eating disorder had been what I had used to cope with my body. I had been sacrificing my mental and physical health for my voice. But now, my voice was on the other side of the line, too.

I finally came out as transgender at 16 and, after a while, started testosterone. The issues that I had been having with my body dissolved, along with my disordered eating. I was so much more comfortable in my body and myself. While I was absolutely catapulting into my new life, finally able to feel the joy that was pushed down with the rest of my identity, the one thing that I mourned was my voice. I missed being able to pick up any piece of music and know that my voice could hit whatever notes were required. I now had to live with uncertainty. After about a year and a half, my voice settled comfortably in a high-tenor range. What had I been worried about? My new voice was great - I could hit all those Dear Evan Hansen notes. This was right about the time I was auditioning for colleges. I was accepted to both of my dream schools and enrolled at Baldwin Wallace University. Then, three weeks before I arrived on campus, my voice made a major shift.

The first assignment of the year was to audition for the fall show. I had chosen my songs at the beginning of the summer and could no longer hit the notes required. I was surrounded by future-Broadway-star peers and felt so lost. I had always been a 'singer first,' but no longer knew how to operate my instrument. I felt untalented. I felt like I didn't deserve to have been admitted to such a prestigious program. I was worried I might have to change the direction of my career.

It has taken a while for me to regain confidence in my voice and learn how to navigate its many new avenues. For the majority of my freshman year, I was terrified of my upper register and was afraid to practice. It was painful to not be able to hit soaring high notes that I previously had access to, and I didn't want to demonstrate to myself that I could no longer hit them.

Something I have learned as a trans performer is that time away from performing can be invaluable. Before college, I took breaks from dancing when my dysphoria got to be too much, I took a break from performing entirely for a while after I came out, and back home after my first year of college, I decided not to sing for a month. I didn't sing until I wanted to, until I wanted to start exploring my upper range. While my freshman year was extremely difficult, I can safely say that I am very excited about the direction my voice is headed. My voice seems to have settled and my upper range is opening back up. I am gaining more and more confidence in it every day. My voice suits me much more now than it did before, and I am finally starting to sing the songs that I always wanted to sing.

Singing is an important part of the musical theatre world, but many things need to be improved in order to make it accessible and enjoyable for trans students and performers. Here are a few ways to help trans and nonbinary singers feel more comfortable:

We need to get rid of the idea that certain vocal ranges denote certain genders. We can all name a cisgender singer whose vocal range sits outside of what we consider 'typical' for their gender. We need to stop using terms like 'countertenor' and 'contralto.' If you are talking about people whose voices fall in the alto range, call them an alto, regardless of gender. If you are calling for tenors and basses to sing a part, ask for 'tenors and basses,' not 'men.' People of all genders fit into every vocal distinction.

Far too many trans voices have been harmed because they are trying to fit a sound their voice is not designed to produce. Our voices are marvelous, beautiful instruments, whether or not they conform to cis-normative standards. If we are best for a role, hire us and modulate the key. It truly is that simple.

Some of our voices are shifting and changing. Have multiple keys ready for when they grow. This was something that my college voice teacher has done that has been incredibly helpful as we became acquainted with my new voice.

Often hormone therapies and certain gender-affirming surgeries can affect our singing voices. Voice teachers, directors, music directors, etc. should educate themselves on how our voices work. Even with hormone replacement therapy, trans voices often operate differently than their cis counterparts. Those who plan to work with singers should educate themselves on these differences. I recommend reading "The Singing Teacher's Guide to Transgender Voices" by Liz Jackson Hearns and Brain Kremer.

Vocal dysphoria is the discomfort that some trans people feel regarding their voice as it relates to their gender. It can come up at any time. There have been lessons where I have experienced vocal dysphoria and became overwhelmed and an instructor gotten angry or kept pushing. There may be certain parts of our voices that we are only rarely comfortable using. Please be patient with us.

Some of us are comfortable singing songs written for people with the gender we were assigned at birth. Some of us are not. Pronouns in songs can be changed, keys can be modulated. Absolutely provide suggestions for repertoire, but become comfortable with us saying no.

The journey through one's new voice can be incredibly frightening and extremely difficult, but the implementation of practices that allow space for students and performers to learn and grow will not only make them more comfortable, it will make space for trans artists in the industry going forward.

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Student Blog: My Vocal Journey Through Testosterone and 6 Things Theatre Needs to do for Trans Voices - Broadway World

First Patient Receives Next-Generation Androgen Biosynthesis Inhibitor for Metastatic Prostate Cancer – Targeted Oncology

Posted: July 3, 2021 at 1:51 am

PRL-02 formulation of abiraterone decanoate that was designed to be used with hormone therapy to treat prostate tumors without causing adverse liver and drug-drug interaction effects. Multiple studies have already demonstrated the potential of androgens for the treatment of this disease, according to the press release. Now, following a 3 + 3 dose-escalation design, the study of PRL-02 with evaluate its ability to suppress testosterone as a primary end point and its safety and tolerability as a secondary end point.

PRL-02 may provide improved bioavailability and convenience over the currently available therapies while also providing patients a potentially safer treatment option than the approved androgen biosynthesis inhibitors said Robert Dreicer, MD professor of medicine and urology at the University of Virginia. I am personally intrigued by the PRL-02 profile and its potential to be a clinically meaningful new option for the treatment of patients with metastatic prostate cancer.

Patients with metastatic prostate cancer included in cohort 1 of the study will receive PRL-02 at 180 mg. In cohort 2, the dosing of the agent is escalated to 360 mg, then to 720 mg in cohort 3 and 1260 mg in cohort 4. In all cohorts, PRL-02 is given as a 10 mL vial containing 990 mg of abiraterone decanoate in 5.5 mL of solution. Further, patients treated in the dose-expansion cohort will receive the recommended phase 2 dose of PRL-02 as determined in the phase 1 portion.

According to the studys protocol, those receiving treatment will remain on the study until their serum testosterone is >1 ng/dL on 2 sequential determinations starting on Day 21 through Day 77, or until they experience unacceptable toxicity, withdraw their consent, at the discretion of the investigator, or following 4 complete cycles of therapy.

The study is actively recruiting patients in treatment sites in Arizona, Indiana, Maryland, Nebraska, New Mexico, and South Carolina. Those eligible are patients with metastatic prostate cancer who have undergone orchiectomy or ongoing gonadotropin-releasing hormone agonist or antagonist therapy for at least 3 months prior to the time of screening and who have an ECOG performance status of 0 or 1, adequate bone marrow reserve, adequate renal and hepatic function, and serum albumin of 3 gm/dL and serum potassium of 3.5 mEq/L.

Metastatic castration-resistant prostate cancer patients with hepatic metastases or known central nervous system metastases are grounds for exclusion from the study. Patients are also ineligible to enroll if they present with another active neoplastic disease that requires concurrent anti-neoplastic treatment, have undergone major surgery or trauma within 4 weeks of screening for the study or present with visceral metastatic disease or impending fracture due to bone metastases.

In terms of comorbidities and medical history, patients cannot have a history of impaired pituitary or adrenal gland function, need systemic glucocorticoids greater than replacement doses, or of prior myocardial infarction, stroke or transient ischemic attack, or who have an uncontrolled inter-current illness, including but not limited to, ongoing or active infection, New York Heart Association Class 3 or 4 congestive heart failure, uncontrolled hypertension, unstable angina pectoris, uncontrolled cardiac arrhythmia, active interstitial lung disease, poorly controlled diabetes, or psychiatric illness/social situations, or substance abuse.

Reference:

Propella announces first patient dosed in phase 1/2a trial of PRL-02 for treatment of metastatic prostate cancer. News release. Propella Therapeutics, Inc. June 29, 2021. Accessed June 29, 2021. https://bit.ly/3qy4Whs

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First Patient Receives Next-Generation Androgen Biosynthesis Inhibitor for Metastatic Prostate Cancer - Targeted Oncology


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