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BetterMe: Weight Loss Workouts on the App Store

Posted: May 6, 2018 at 3:41 am

BetterMe helps you achieve your personal wellness objectives by building and modifying your meal and workout plans.

Thousands of satisfied customers have rated the app 5 stars and left their enthusiastic reviews on the App Store. BetterMe lets you have the expertise of fitness and diet specialists in the palm of your hand without ever having to hit the gym.

Currently, BetterMe is available in three languages, Spanish, English and German.

Start off with BetterMe by answering these questions about your wellness:

a) What are your goals? Do you want to lose weight, or gain muscle mass and get fit?b) What is your fitness level?c) What are your diet and meal preferences?

All you have to do next is wait for the custom workout and free meal plans from BetterMe and check in with the app daily to achieve your dream health, weight loss and fitness results. BetterMe app offers a plethora of exercises and workout plans to choose from that vary in length and intensity. No special equipment needed, only your dedication and resolve.

To build on the benefits of constant physical workouts, BetterMe offers a list of well-balanced and sensible meal plans compiled on the basis of your dietary habits and needs. Unlike most weight loss and fitness apps, we will accompany you on every step of your journey to a healthier, more fit you by:

– offering tips and guides on proper diet;- helping you set your customized weekly meal plans;- offering you workouts to get rid of excessive fat;- offering you sprint interval workouts;- demonstrating every step in our instructive videos;- providing tips on proper exercise execution.

This is how BetterMe fitness and app will help you follow the wellness and weight loss plans youve set:

– We help you set a goal;- We help you build endurance;- We offer research and science-based workout routines;- We oversee your meals and diet.

BetterMe will send you reminders and motivating messages to encourage your training and healthy diet.

All BetterMe users can try the app for free by signing up to a free trial period. During the free 7-day trial, youll get the star treatment and will be able to try the fitness and diet features.BetterMe app users can choose the subscription plan that suits their needs best, by considering the workout, the diet, and the costs. Our Premium subscription plan offers unlimited access to every level of every imaginable workout routine in exchange for a single payment. For your convenience, BetterMe subscriptions are set to automatically renew within the 24-hour period prior to the subscription end date. You can cancel your subscription at any moment, too.

BetterMe is integrated with the Health kit, so you can find your activities data in the Health App.

Constructive criticism is always welcome. Our fitness, weight loss and diet specialists, as well as our developers, are working constantly to improve the user experience and cater to a wider range of our customers needs.Contact our client support via support@betterme.tips.

Read more about our Terms and Conditions here – https://bttrm.com/info/terms-ios.html

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BetterMe: Weight Loss Workouts on the App Store

Growing Fat Body

Posted: May 2, 2018 at 11:41 pm

ethiknacon posted a photo:

Growing Fat Body

Backdrop: Backdrop City – Instagramish Area
FOXCITY. Photo Booth – Rose Bathroom (For Selfies) (Rez)
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Different fat sizes of the Vivendi Body v2, coming soon!

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Growing Fat Body

Growing Pudgy Body

Posted: May 2, 2018 at 11:41 pm

ethiknacon posted a photo:

Growing Pudgy Body

Backdrop: Backdrop City – Instagramish Area
Pseudo- Pia Bathroom Backdrop RARE
maps.secondlife.com/secondlife/Backdrop%20City/87/159/1739

Different pudgy sizes of the Vivendi Body v2, coming soon!

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Growing Pudgy Body

Hiatal (Nissen Fundoplication, Paraesophageal) Hernias …

Posted: May 2, 2018 at 11:41 pm

After Surgery

Expect stay in the hospital one to two days after this procedure. On the morning after your procedure you will get a swallowing study to make sure everything is in the proper place. After that, you will start on a liquid diet.

This surgical procedure does require diet restrictions after surgery. You will need to stay on a liquid/soft diet for approximately 3 weeks after surgery. During that time, you can try or experiment with eating soft, mushy foods like tuna, mashed potatoes, eggs, cottage cheese, and thick soups. The reason for liquids is that there will be some swelling in your esophagus where your hernia was repaired. You may also notice that swallowing feels a little tight this will improves as the swelling goes down. With time, you will be able to digest foods normally. ALSO, DO NOT DRINK CARBONATED BEVERAGES FOR THREE WEEKS.

Some patients find that their appetite is poor or that foods dont taste well after surgery. This is a normal result of the stress of surgery and manipulation inside the belly your appetite should return in several weeks. If you do not eat, this is OK; the most important thing is to drink liquids. If you find you are persistently nauseated or unable to take in liquids, contact our office and let us know.

It is OK to shower starting around 36 hours after surgery. If you have little patches of white gauze or band-aides on the incisions, take off the gauze/band-aides before showering.

You might see little pieces of tape (called steri-strips) directly attached to your skin. It is OK to get these little tapes wet in the shower. The tapes will begin to peel up on the ends 7-10 days after surgery at this point they have done their job and it is OK for you to peel them the rest of the way off if you wish. You do not have to have them on when you come for your postoperative visit.

No baths, pools or hot tubs for two weeks.

We try to close your incisions to leave the smallest possible scar. Do not put any ointment or other medication on your incisions it will not make them heal better.

There are no significant restrictions on activity after surgery. That means it is OK to walk, climb stairs, have sexual intercourse, mow the lawn, or exercise as long as it doesnt hurt. In fact, returning to normal activity as soon as possible will most likely enhance your recovery. However, if it doesnt feel good, dont do it. Take it easy and let the pain be your guide. Avoid heavy lifting to aide in the healing of your incisions.

You may also feel easily fatigued and washed out for a week or two following the surgery. These factors will put some limitations on your activity, but you will not cause any damage even if some soreness is experienced.

Everyone has different motivations toward their job, and thus everyone returns to work at different times. As a rough guide, most people take at least 1-2 weeks off prior to returning to work. If you need particular documentation for your job, call the office.

You will usually be able drive when you have not needed the narcotic (prescription) pain medications for two days.

The first bowel movement may occur anywhere from 1-5 days after surgery as long as you are not nauseated or having abdominal pain this variation is acceptable. Remember that it is very common to pass a lot more gas from your rectum than you used to this is because you will not be able to really belch. Some patients also find that they have diarrhea or loose bowels for the first days after their hernia repair in the vast majority of cases, the bowel function normalizes with time. Constipation may also be common due to the pain medication. We recommend taking Milk of Magnesia (2 tablespoons; twice a day) while taking the pain pills to avoid constipation.

Call your surgeons office if any of the following occur:

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Hiatal (Nissen Fundoplication, Paraesophageal) Hernias …

Diet Guide | Inflammatory Bowel Disease Center …

Posted: May 2, 2018 at 11:41 pm

Dietary Strategies to Help Manage and Reduce IBD Symptoms

Inflammatory bowel disease (IBD) is not caused, nor can it be cured, by what you eat. Doctors and dietitians agree, however, that food may play some role in the underlying inflammatory process that causes IBD symptoms.

Certain foods may aggravate symptoms, while others may calm them and promote healing. Therefore, paying attention to what you eat and how your body responds to different foods is an important component of a total treatment plan for IBD.

A diet plan can supplement but should never replace medical treatment for IBD. Always take your medications exactly as prescribed by your doctor.

Inflammatory bowel disease is often associated with malnutrition due to:

Malnourishment and weight loss in women and girls can impact hormone levels and result in menstrual changes or missed periods. In children and teenagers, it can slow their growth and development.

Patients should talk to a doctor or dietitian to create a well-balanced diet customized for them based on the disease they have (Crohns disease or ulcerative colitis); the location and extent of their disease; and whether their disease is active or in remission.

The dietary recommendations listed here are intended to provide some very general guidelines only. There is no single eating plan that works for everyone with IBD and an ongoing collaboration with a licensed dietitian or your doctor is recommended.

Even when your symptoms are inactive, it is very important to eat a balanced diet with lots of variety. IBD medications tend to be more effective in well-nourished individuals, so try to include the following in your diet every day:

Although what you eat will not completely resolve most IBD symptoms, eating or not eating certain foods can often help to minimize them and ease discomfort. It is also advisable to eat smaller portions, more frequently.

*Many people find that it is helpful to keep a food journal to track their bodys response to certain foods. This can help to identify trigger foods to avoid. However, you should always talk to your doctor before totally eliminating any foods or food groups from your diet as this can lead to nutritional deficiencies.

Excerpt from:
Diet Guide | Inflammatory Bowel Disease Center …

Autoimmune gut-repair diet Autoimmune protocol | Dr. K. News

Posted: May 1, 2018 at 10:41 pm

Many people wonder what they can do immediately to manage their chronic health condition. The science can be confusing and complex, especially to those with Hashimotos hypothyroidism and other autoimmune diseases, because these disorders can lead to brain fog, fatigue, and loss of cognitive function that make it hard to figure out what to do next.

What people frequently fail to realize is that underlying all of these conditions is the most important foundation of all, and something you have the power to change right now your diet.

In this article, Ill give you the dietary basics for the autoimmune protocol (AIP). The autoimmune protocol is an effective diet and lifestyle protocol that helps autoimmune patients overcome the core underlying factors preventing recovery, including inflammation, leaky gut, hormone imbalances, blood sugar imbalances, micronutrient deficiencies, and immune system dysregulation.

The autoimmune protocol diet is an elimination and reintroduction protocol: For a time you eliminate foods that are known to drive inflammation and resulting symptoms, and then you reintroduce foods methodically to rule out reactivity.

The optimal end result is a diet and lifestyle that support your health while avoiding factors that undermine it.

The diet explained here is stricter than the one in my books. It became clear, based on the research and the experience of many people, that a more stringent approach is often necessary. The diet must be very basic and simple so as not to trigger inflammation in the intestines and further worsen leaky gut and autoimmune flare-ups.

The literature identifies nutritional and herbal compounds that can facilitate your gut-repair progress, which I will introduce in the second edition of the thyroid book, or which your practitioner can help you with. However, this diet is powerful therapy on its own.

In any autoimmune condition, there are several key problem areas that underlie symptoms. The autoimmune protocol seeks to address each of these, bringing the body back into balance so it can function properly.

These are always good basic guidelines with which to start whether you are waiting to work with a practitioner or are going it alone:

When considering this diet the fist thing people ask is what can they eat.In fact youll be eating the way people ate for most of human history theres plenty of food that doesnt come from a factory or an industrialized farm. Of course, if you have an intolerance to any of these foods, dont eat it just because its on this list.

Most organic vegetables:Include as much variety as possible, making sure to include the full color spectrum; anise, arrugula, artichoke, asparagus, beets and their greens, bok choy, broccoli, cabbage, carrots, cauliflower, celery, chives, cucumbers, garlic, kale, kohlrabi, leeks, lettuce, mustard greens, olives, onions, parsley, radishes, rhubarb, shallots, spinach, squash, sweet potatoes and yams (not true potatoes), water chestnuts, watercress, zucchini, etc. Vegetables from the brassica family (broccoli, kale, etc.) are no longer considered bad for thyroid function; please see this article for more information.

Quality meats:beef, chicken, bison, pork, lamb, turkey, and wild game. Select hormone-free and antibiotic-free chicken, turkey, and lamb. Chicken has high Omega 6 content; eat in moderation, and if you consume more, also eat a lot of Omega 3 oils to compensate (see bottom of this section for proper ratios). Select beef that is grass fed, hormone free, and antibiotic free. Best choice arelocally-raised grass-fed and pastured meats; second best is organic. Avoid factory-farmed meats that contain antibiotics and hormones.

Organ meats and offal: heart, liver, kidney, tongue, and bone broth. An important concentrated form of nutrients including vitamins, minerals, healthy fats, and essential amino acids.

Glycine-rich foods: Include foods containing connective tissue, organ meat, joints, skin, or bone broth.

Fish and shellfish: Seek out ocean-caught cold water, low mercury fish with high fat content. Swordfish, most tuna, and king mackerel are very high in mercury.

Quality fats: pasture-raised, grass-fed animal fats, fatty cold water fish, olive oil, avocado oil, coconut oil, low-mercury Omega 3 supplements.

Low glycemic organic fruits: apples, apricots, avocados, berries, cherries, grapefruit, lemons, peaches, pears, plums, etc. Keep sugar intake between 10 and 20g per day.

Edible mushrooms: Mushrooms are generally fine for most individuals. However, some people with autoimmune conditions may react to immune-stimulating fungi such as Maitake and mushroom-derived beta-glucan, so monitor your response.

Probiotic and fermented foods: sauerkraut, kimchi, pickled ginger, fermented cucumbers, coconut yogurt (guar-gum free), kombucha, water kefir, coconut milk kefir, supplements, etc. You may need to make your own or buy one of the few brands that are genuinely fermented and free of sugars or additives. Also, search for information about anaerobic fermented foods in air-tight containers; these ferments do not produce histamines that some people react to (including rashes, digestive upset, inflammation) commonly found in aerobic, or open, ferments typically using mason jars.

Coconut:coconut aminos, coconut milk (guar gum free), coconut water and coconut water vinegar, coconut cream (not concentrate), and coconut oil. Whole coconut products (coconut butter, coconut cream concentrate, coconut flakes and chips, unsweetened coconut yogurt, fresh coconut) have high inulin fiber and moderately high phytic acid, which causes some individuals digestive issues consume in moderation until you know your tolerance level.

Noodles:Shirataki yam noodles (sold in Asian grocery stores and some natural food stores) are fine, but avoid the noodles that contain tofu (soy).

Herbs and spices: basil, cilantro, cinnamon, coriander, clove, cumin, garlic, ginger, horseradish, lemongrass, mace, mint, oregano, parsley, rosemary, sage, saffron, sea salt, thyme, turmeric (black pepper is considered a reintroduction item). Avoid iodized salt unless you are deficient in iodine.

Vinegars: apple cider, balsamic, champagne, coconut, red wine, sherry, ume plum, white wine. Avoid grain-based vinegars: rice and distilled white.

Teas: black, green white, yerba mate (avoid caffeine if you have adrenal fatigue).

Other: herbal teas, carob, rooibos tea, deglycyrrhizinated licorice (DGL) (but not whole licorice root), vanilla extract (if cooked). In moderation: fructose (in fruit and starchy vegetables), pomegranate molasses. Very occasionally: maple syrup and maple sugar, honey, dried fruit, dates and date sugar, molasses, unrefined cane sugar (sucanat, evaporated cane juice, muscovado). Each person has unique tolerance to sugars monitor your response.

Grey areas depending on individual sensitivities: legumes with edible pods (green beans, snow peas). Whole bean coffee in moderation (caution: many instant coffees show gluten contamination). Sugars: Some people have strong reactions to even small amounts of sugars; monitor your response. Seaweeds (high in iodine): Some people with Hashimotos may not do well with additional iodine in the diet.

A note on fatty acids: Consuming a proper ratio of omega-6 to omega-3 fatty acids is key for minimizing inflammation in the body. Too much omega-6 is highly inflammatory, so its important to get enough omega-3 (anti-inflammatory) to compensate. The average American ratio is close to 25 parts omega-6 to 1 part omega-3, resulting in high levels of inflammation. Researchers recommend a ratio of omega-6 to omega-3 fatty acids that ranges from 1:1 to 4:1 for optimal health and prevention of disease.

The autoimmune protocol diet is an elimination and reintroduction protocol: For a time you eliminate foods that are known to drive inflammation and resulting symptoms, and then you reintroduce foods methodically to rule out reactivity.

Everyone asks how long the elimination phase might take, because nobody likes to make major changes in their habits. Timing on reintroductions depends on the individual. A good rule of thumb is to wait for reintroductions until you notice a marked improvement in your symptoms and quality of life; for some thats 30 days, for others its months or even a year.

It may take time to unwind the self-perpetuating inflammatory cycles that lie beneath your symptoms, and its important to not rush into reintroductions. If you begin reintroductions while you are still highly symptomatic you will not be able to gauge whether or not a reintroduced food is causing a reaction and youll need to start over again.

Your stress level, sleep quality, exercise level, nutrient intake, genetics, oral tolerance and underlying health issues will affect your reactions to foods. This affects when you can start reintroductions, and also means as your status with these factors improves over time, you may be able to reintroduce certain foods that previously tested as reactive.

Sometimes, one successfully reintroduces a food, then symptoms start to return. If this happens to you, it may mean you need to stay away from a food you thought was a good addition, until a later date or even permanently.

Symptoms can be represented by any change; digestive upset, mood changes, fatigue, pain, sleep issues, brain fog, skin rash, etc.

IMPORTANT: If you have a reaction to a food reintroduction, you must wait until those symptoms are completely gone before moving on to the next reintroduction.

For more details on how to manage reintroductions properly, please consult with your healthcare practitioner.

Some foods are more likely cause a reaction than others. Its best to reintroduce foods lowest on that list first, ending with the most-likely items. If you have had food sensitivity testing done, leave any foods you have a diagnosed sensitivity for until the end of reintroductions. A general order of reintroduction is:

Egg

Egg yolks first: Most people tolerate the yolks well; intolerance is more common to the whites. Research shows soy protein is transferred to eggs; soy is a common chicken feed, so if you are intolerant to soy, you may find soy-fed chicken eggs are reactive for you.

Seeds before nuts

Introduce one item at a time, not mixed: seed-based spices (no nightshades), oils, butters, flours; raw nuts (soaked); toasted (beware store-bought seeds roasted in non-compliant oils); cocoa; coffee (in moderation).

Dairy

Grass-fed ghee then butter; raw goat yogurt/kefir, milk, cheese; raw cow dairy in the same order. Why raw, why this order? Raw dairy has live enzymes that make it easier to digest. Dairy has three components; butterfat, lactose and casein. Butterfat doesnt cause a problem for many people; intolerance is more common for lactose and casein. Therefore ghee and butter come first. Goat dairy is easier to digest than cow dairy.

Nightshades

These come last because they are the most common food intolerance for those with autoimmune conditions, and if you have an inflammatory reaction, it takes longer to calm down and continue with reintroductions. Be sure to reintroduce one vegetable at a time. You might react to all, or only to some.

Consider never consuming

TomatoesNSAIDS (they disrupt gut health)Grains/Gluten (most reactivity is related to molecular mimicry).Reintroduction of other foods depends on your individual health history and needs.

Grains and legumes are high in proteins called lectins. Lectins have been shown to degrade the intestinal barrier, adding to leaky gut. They can also be transported through the damaged intestinal wall into the bloodstream, where they may bind to insulin receptors and leptin receptors. Some believe lectins may also have the ability to desensitize these receptors, thus contributing to insulin resistance and leptin resistance.

When transported through the gut wall into the blood stream, leptins can also set off an immune reaction that further damages the intestinal wall and sets off systemic inflammation, further supporting the autoimmune reaction.

Grains, legumes and some other foods present problems for other reasons. Research has shown that many gluten-intolerant people cross-react with other foods. In other words, their body erroneously recognizes other foods as gluten and reacts with an immune response that destroys not only the food proteins, but bodily tissue.

Not surprisingly, most grains fall into the category of top 24 foods most often to cause cross-reactivity, including amaranth and quinoa.

Other common cross-reactive foods include dairy, chocolate, sesame,and instantcoffee. Fortunately it is now possible to test which foods might be provoking a cross-reaction to gluten, which you can read abouthere.

I tell all my gluten-free patients to avoid corn, even though this contradicts the advice on many gluten-free websites. The protein in corn is similar enough to that in wheat and wheat-like grains that it can provoke an immune response. Also, corn has been bred over the years to resist pests. Unfortunately this bred into corn a compound called fucosamine, which is carcinogenic.

Tree nuts are one of the top allergens and food sensitivities. Leaky gut is exceedingly common in autoimmune patients, and it increases the likelihood of developing food allergies and sensitivities. By removing seeds and nuts from the diet during elimination phase, one is better able to determine if a sensitivity exists.

In addition, the fiber in nuts and seeds can contribute to gut irritation.

Nighshades contain digestion-resistant and gut-irritating lectins, saponins, and capsaicin (a steroidal stimulant) that can contribute to leaky gut, as well as pass through the gut lining and contribute to systemic inflammation and immune reactivity.

For those battling a history of weight issues or an eating disorder, this diet can be filled with emotional triggers. In these cases I highly recommendsupport for underlying subconscious beliefs about food, eating, and your body. Ideas include hypnotherapy, emotional freedom technique (EFT) workshops or instruction, guided meditations and visualizations. You will find plenty of instruction online.

Subconscious beliefs aside, many are pleasantly surprised to find cravings and obsessions with food diminish or disappear once they remove immune reactive foods, stabilize blood sugar, and eat a nutrient-dense diet.

Many embarking on this diet are entering new territories of food. You may need to shop at different stores or order things online. I have supplied a list of popular sources on theresourcepage.

The autoimmune diet protocol can seem daunting at first, and planning is essential to success. Fortunately, ample support exists on the internet today for a diet such as this. There are online tribes for many variations of diet including paleo, primal, GAPS, SCD, and AIP.

You must have the right foods on hand at all times; its helpful to batch cook so you have meals at hand and are not tempted to fall off the wagon. Thankfully, there are now plenty of great websites that offer recipes compliant with the autoimmune diet, also called the Autoimmune Protocol or AIP.

This dietary and lifestyle protocol is powerful on its own, however to boost the repair and recovery effects, please work with a qualified healthcare practitioner who understands the connections between gut health and the brain, immune system, and endocrine system. He or she can provide you with proven nutritional compounds that have been shown to significantly aid the process of repair and recovery and unwind self-perpetuating inflammatory cycles in the gut and body.

To learn more about why these foods are so important to include or avoid, please see my Oral Tolerance and Save Your Brain courses.

I am working on a book dedicated to leaky gut, gluten, and autoimmunity. I also highly suggest my newest bookWhy Isnt My Brain Working?to learn about ways your brain plays a role in your gut and immune health.

More here:
Autoimmune gut-repair diet Autoimmune protocol | Dr. K. News

DIETS DON’T WORK 3RD ED Paperback – amazon.com

Posted: May 1, 2018 at 10:41 pm

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Yuba’s Leverage

Posted: April 29, 2018 at 12:41 am

sjrankin posted a photo:

Yuba's Leverage

Yuba weighs so much that he can extend himself over the table pretty far without falling off. If he did fall off, we’d have to patch a hole in the floor…

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Yuba’s Leverage

Human chorionic gonadotropin – Wikipedia

Posted: April 28, 2018 at 5:40 am

Human chorionic gonadotropin (hCG) is a hormone produced by the placenta after implantation.[1][2] The presence of hCG is detected in some pregnancy tests (HCG pregnancy strip tests). Some cancerous tumors produce this hormone; therefore, elevated levels measured when the patient is not pregnant may lead to a cancer diagnosis and, if high enough, paraneoplastic syndromes, however, it is not known whether this production is a contributing cause, or an effect of carcinogenesis. The pituitary analog of hCG, known as luteinizing hormone (LH), is produced in the pituitary gland of males and females of all ages.[1][3]

Regarding endogenous forms of hCG, there are various ways to categorize and measure them, including total hCG, C-terminal peptide total hCG, intact hCG, free -subunit hCG, -core fragment hCG, hyperglycosylated hCG, nicked hCG, alpha hCG, and pituitary hCG. Regarding pharmaceutical preparations of hCG from animal or synthetic sources, there are many gonadotropin preparations, some of which are medically justified and others of which are of a quack nature. As of December6, 2011[update], the United States Food and Drug Administration has prohibited the sale of “homeopathic” and over-the-counter hCG diet products and declared them fraudulent and illegal.[4][5][6]

Human chorionic gonadotropin is glycoprotein composed of 237 amino acids with a molecular mass of 36.7 kDa, approximately 14.5 hCG and 22.2kDa hCG.[7]

It is heterodimeric, with an (alpha) subunit identical to that of luteinizing hormone (LH), follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and (beta) subunit that is unique to hCG.

The two subunits create a small hydrophobic core surrounded by a high surface area-to-volume ratio: 2.8 times that of a sphere. The vast majority of the outer amino acids are hydrophilic.[10]

Human chorionic gonadotropin interacts with the LHCG receptor of the ovary and promotes the maintenance of the corpus luteum during the beginning of pregnancy. This allows the corpus luteum to secrete the hormone progesterone during the first trimester. Progesterone enriches the uterus with a thick lining of blood vessels and capillaries so that it can sustain the growing fetus[citation needed].

Due to its highly negative charge, hCG may repel the immune cells of the mother, protecting the fetus during the first trimester[citation needed]. It has also been hypothesized that hCG may be a placental link for the development of local maternal immunotolerance[citation needed]. For example, hCG-treated endometrial cells induce an increase in T cell apoptosis (dissolution of T cells). These results suggest that hCG may be a link in the development of peritrophoblastic immune tolerance, and may facilitate the trophoblast invasion, which is known to expedite fetal development in the endometrium.[11] It has also been suggested that hCG levels are linked to the severity of morning sickness or Hyperemesis gravidarum in pregnant women.[12]

Because of its similarity to LH, hCG can also be used clinically to induce ovulation in the ovaries as well as testosterone production in the testes. As the most abundant biological source is women who are presently pregnant, some organizations collect urine from pregnant women to extract hCG for use in fertility treatment.[13][14]

Human chorionic gonadotropin also plays a role in cellular differentiation/proliferation and may activate apoptosis.[15]

Naturally, it is produced in the human placenta by the syncytiotrophoblast.

Like any other gonadotropins, it can be extracted from the urine of pregnant women or produced from cultures of genetically modified cells using recombinant DNA technology.

In Pubergen, Pregnyl, Follutein, Profasi, Choragon and Novarel, it is extracted from the urine of pregnant women. In Ovidrel, it is produced with recombinant DNA technology.[16]

Regarding endogenous forms of hCG, there are various ways to categorize and measure them, including total hCG, C-terminal peptide total hCG, intact hCG, free -subunit hCG, -core fragment hCG, hyperglycosylated hCG, nicked hCG, alpha hCG, and pituitary hCG.

Regular hCG is the main form of hCG associated with the majority of pregnancy and in non-invasive molar pregnancies. This is produced in the trophoblast cells of the placental tissue. Hyperglycosylated hCG is the main form of hCG during the implantation phase of pregnancy, with invasive molar pregnancies, and with choriocarcinoma.

Regarding pharmaceutical preparations of hCG from animal or synthetic sources, there are many gonadotropin preparations, some of which are medically justified and others of which are of a quack nature.

Blood or urine tests measure hCG. These can be pregnancy tests. hCG-positive indicates an implanted blastocyst and mammalian embryogenesis. These can be done to diagnose and monitor germ cell tumors and gestational trophoblastic diseases.

Concentrations are commonly reported in thousandth international units per milliliter (mIU/ml). The international unit of hCG was originally established in 1938 and has been redefined in 1964 and in 1980.[17] At the present time, 1 international unit is equal to approximately 2.351012 moles,[18] or about 6108 grams.[19]

Most tests employ a monoclonal antibody, which is specific to the -subunit of hCG (-hCG). This procedure is employed to ensure that tests do not make false positives by confusing hCG with LH and FSH. (The latter two are always present at varying levels in the body, whereas the presence of hCG almost always indicates pregnancy.)

Many hCG immunoassays are based on the sandwich principle, which uses antibodies to hCG labeled with an enzyme or a conventional or luminescent dye. Pregnancy urine dipstick tests are based on the lateral flow technique.

The following is a list of serum hCG levels. (LMP is the last menstrual period dated from the first day of the last menstrual period.) The levels grow exponentially after conception and implantation.[22]

The ability to quantitate the hCG level is useful in the monitoring germ cell and trophoblastic tumors, follow-up care after miscarriage, and in diagnosis of and follow-up care after treatment of ectopic pregnancy. The lack of a visible fetus on vaginal ultrasound after the hCG levels have reached 1500 mIU/ml is strongly indicative of an ectopic pregnancy.[23] Still, even an hCG over 2000 IU/l does not necessarily exclude the presence of a viable intrauterine pregnancy in such cases.[24]

As pregnancy tests, quantitative blood tests and the most sensitive urine tests usually detect hCG between 6 and 12 days after ovulation.[25] It must be taken into account, however, that total hCG levels may vary in a very wide range within the first 4 weeks of gestation, leading to false results during this period.[26] A rise of 35% over 48 hours is proposed as the minimal rise consistent with a viable intrauterine pregnancy.[24]

Gestational trophoblastic disease like hydatidiform moles (“molar pregnancy”) or choriocarcinoma may produce high levels of hCG (due to the presence of syncytialtrophoblasts- part of the villi that make up the placenta) despite the absence of an embryo. This, as well as several other conditions, can lead to elevated hCG readings in the absence of pregnancy.

hCG levels are also a component of the triple test, a screening test for certain fetal chromosomal abnormalities/birth defects.

A study of 32 normal pregnancies came to the result a gestational sac of 13mm was detected at a mean hCG level of 1150 IU/l (range 800-1500), a yolk sac was detected at a mean level of 6000 IU/l (range 4500-7500) and fetal heartbeat was visible at a mean hCG level of 10,000 IU/l (range 8650-12,200).[27]

Human chorionic gonadotropin can be used as a tumor marker,[28] as its subunit is secreted by some cancers including seminoma, choriocarcinoma, germ cell tumors, hydatidiform mole, teratoma with elements of choriocarcinoma, and islet cell tumor. For this reason, a positive result in males can be a test for testicular cancer. The normal range for men is between 0-5 mIU/mL. Combined with alpha-fetoprotein, -HCG is an excellent tumor marker for the monitoring of germ cell tumors.[citation needed]

Human chorionic gonadotropin injection is extensively used for final maturation induction in lieu of luteinizing hormone. In the presence of one or more mature ovarian follicles, ovulation can be triggered by the administration of HCG. As ovulation will happen between 38 and 40 hours after a single HCG injection,[29] procedures can be scheduled to take advantage of this time sequence,[30] such as intrauterine insemination or sexual intercourse. Also, patients that undergo IVF, in general, receive HCG to trigger the ovulation process, but have an oocyte retrieval performed at about 34 to 36 hours after injection by, a few hours before the eggs actually would be released from the ovary.

As HCG supports the corpus luteum, administration of HCG is used in certain circumstances to enhance the production of progesterone.

In the male, HCG injections are used to stimulate the Leydig cells to synthesize testosterone. The intratesticular testosterone is necessary for spermatogenesis from the sertoli cells. Typical uses for HCG in men include hypogonadism and fertility treatment.

Several vaccines against human chorionic gonadotropin (hCG) for the prevention of pregnancy are currently in clinical trials.[31]

In the case of female patients who want to be treated with HCG Pubergen, Pregnyl:[32] a) Since infertile female patients who undergo medically assisted reproduction (especially those who need in vitro fertilization), are known to often be suffering from tubal abnormalities, after a treatment with this drug they might experience many more ectopic pregnancies. This is why early ultrasound confirmation at the beginning of a pregnancy (to see whether the pregnancy is intrauterine or not) is crucial. Pregnancies that have occurred after a treatment with this medicine are submitted to a higher risk of multiplets. Female patients who have thrombosis, severe obesity, or thrombophilia should not be prescribed this medicine as they have a higher risk of arterial or venous thromboembolic events after or during a treatment with HCG Pubergen, Pregnyl. b)Female patients who have been treated with this medicine are usually more prone to pregnancy losses.

In the case of male patients: A prolonged treatment with HCG Pubergen, Pregnyl is known to regularly lead to increased production of androgen. Therefore: Patients who are suffering from overt or latent cardiac failure, hypertension, renal dysfunction, migraines, or epilepsy might not be allowed to start using this medicine or may require a lower dose of HCG Pubergen, Pregnyl. Also this medicine should be used with extreme caution in the treatment of prepubescent teenagers in order to reduce the risk of precocious sexual development or premature epiphyseal closure. This type of patients’ skeletal maturation should be closely and regularly monitored.

Both male and female patients who have the following medical conditions must not start a treatment with HCG Pubergen, Pregnyl: (1) Hypersensitivity to this medicine or to any of its main ingredients. (2) Known or possible androgen-dependent tumors for example male breast carcinoma or prostatic carcinoma.

In the world of performance-enhancing drugs, HCG is increasingly used in combination with various anabolic-androgenic steroid (AAS) cycles. As a result, HCG is included in some sports’ illegal drug lists.

When exogenous AAS are put into the male body, natural negative-feedback loops cause the body to shut down its own production of testosterone via shutdown of the hypothalamic-pituitary-gonadal axis (HPGA). This causes testicular atrophy, among other things. HCG is commonly used during and after steroid cycles to maintain and restore testicular size as well as normal testosterone production.[33]

High levels of AASs, that mimic the body’s natural testosterone, trigger the hypothalamus to shut down its production of gonadotropin-releasing hormone (GnRH) from the hypothalamus. Without GnRH, the pituitary gland stops releasing luteinizing hormone (LH). LH normally travels from the pituitary via the blood stream to the testes, where it triggers the production and release of testosterone. Without LH, the testes shut down their production of testosterone.[34] In males, HCG helps restore and maintain testosterone production in the testes by mimicking LH and triggering the production and release of testosterone.

If HCG is used for too long and in too high a dose, the resulting rise in natural testosterone and estrogen would eventually inhibit endogenous production of luteinizing hormone via negative feedback on the hypothalamus and pituitary gland.[citation needed]

Professional athletes who have tested positive for HCG have been temporarily banned from their sport, including a 50-game ban from MLB for Manny Ramirez in 2009[35] and a 4-game ban from the NFL for Brian Cushing for a positive urine test for HCG. Mixed Martial Arts fighter Dennis Siver was fined $19,800 and suspended 9 months for being tested positive after his bout at UFC 168.[37]

British endocrinologist Albert T. W. Simeons proposed HCG as an adjunct to an ultra-low-calorie weight-loss diet (fewer than 500 calories).[38] Simeons, while studying pregnant women in India on a calorie-deficient diet, and “fat boys” with pituitary problems (Frlich’s syndrome) treated with low-dose HCG, observed that both lost fat rather than lean (muscle) tissue.[38] He reasoned that HCG must be programming the hypothalamus to do this in the former cases in order to protect the developing fetus by promoting mobilization and consumption of abnormal, excessive adipose deposits. Simeons in 1954 published a book entitled Pounds and Inches, designed to combat obesity. Simeons, practicing at Salvator Mundi International Hospital in Rome, Italy, recommended low-dose daily HCG injections (125IU) in combination with a customized ultra-low-calorie (500 cal/day, high-protein, low-carbohydrate/fat) diet, which was supposed to result in a loss of adipose tissue without loss of lean tissue.[38]

Other researchers did not find the same results when attempting experiments to confirm Simeons’ conclusions, and in 1976 in response to complaints the FDA required Simeons and others to include the following disclaimer on all advertisements:[39]

These weight reduction treatments include the injection of HCG, a drug which has not been approved by the Food and Drug Administration as safe and effective in the treatment of obesity or weight control. There is no substantial evidence that HCG increases weight loss beyond that resulting from caloric restriction, that it causes a more attractive or “normal” distribution of fat, or that it decreases the hunger and discomfort associated with calorie-restrictive diets.

1976 FDA-mandated disclaimer for HCG diet advertisements

There was a resurgence of interest in the “HCG diet” following promotion by Kevin Trudeau, who was banned from making HCG diet weight-loss claims by the U.S. Federal Trade Commission in 2008, and eventually jailed over such claims.[40]

A 1976 study in the American Journal of Clinical Nutrition[41] concluded that HCG is not more effective as a weight-loss aid than dietary restriction alone.[42]

A 1995 meta analysis found that studies supporting HCG for weight loss were of poor methodological quality and concluded that “there is no scientific evidence that HCG is effective in the treatment of obesity; it does not bring about weight-loss or fat-redistribution, nor does it reduce hunger or induce a feeling of well-being”.[43]

On November 15, 2016, the American Medical Association (AMA) passed policy that “The use of human chorionic gonadotropin (HCG) for weight loss is inappropriate.”[44]

There is no scientific evidence that HCG is effective in the treatment of obesity. The meta-analysis found insufficient evidence supporting the claims that HCG is effective in altering fat-distribution, hunger reduction, or in inducing a feeling of well-being. The authors stated the use of HCG should be regarded as an inappropriate therapy for weight reduction In the authors opinion, Pharmacists and physicians should be alert on the use of HCG for Simeons therapy. The results of this meta-analysis support a firm standpoint against this improper indication. Restraints on physicians practicing this therapy can be based on our findings.

According to the American Society of Bariatric Physicians, no new clinical trials have been published since the definitive 1995 meta-analysis.[45]

The scientific consensus is that any weight loss reported by individuals on an “HCG diet” may be attributed entirely to the fact that such diets prescribe calorie intake of between 500 and 1,000 calories per day, substantially below recommended levels for an adult, to the point that this may risk health effects associated with malnutrition.[46]

Controversy about, and shortages[47] of, injected HCG for weight loss have led to substantial Internet promotion of “homeopathic HCG” for weight control. The ingredients in these products are often obscure, but if prepared from true HCG via homeopathic dilution, they contain either no HCG at all or only trace amounts. Moreover, it is highly unlikely that oral HCG is bioavailable due to the fact that digestive protease enzymes and hepatic metabolism renders peptide-based molecules (such as insulin and human growth hormone) biologically inert. HCG can likely only enter the bloodstream through injection.

The United States Food and Drug Administration has stated that over-the-counter products containing HCG are fraudulent and ineffective for weight loss. They are also not protected as homeopathic drugs and have been deemed illegal substances.[48][49] HCG is classified as a prescription drug in the United States and it has not been approved for over-the-counter sales by the FDA as a weight loss product or for any other purposes, and therefore neither HCG in its pure form nor any preparations containing HCG may be sold legally in the country except by prescription.[4] In December 2011, FDA and FTC started to take actions to pull unapproved HCG products from the market.[4] In the aftermath, some suppliers started to switch to “hormone-free” versions of their weight loss products, where the hormone is replaced with an unproven mixture of free amino acids[50] or where radionics is used to transfer the “energy” to the final product.

In order to induce a stronger immune response, some versions of human chorionic gonadotropin-based anti-fertility vaccines were designed as conjugates of the subunit of HCG covalently linked to tetanus toxoid.[31][51] It has been alleged that a non-conjugated tetanus vaccine used in developing countries is laced with a human chorionic gonadotropin based anti-fertility drug[52] and is distributed as a means of mass sterilization.[53] This charge has been vigorously denied by the World Health Organization (WHO) and UNICEF.[54] Others have argued that a hCG laced vaccine could not be used for sterilization since the effects of the anti-fertility vaccines are reversible (requiring booster doses to maintain immunity) and a non-conjugated vaccine is likely to be ineffective.[55][56] Finally, independent testing of the tetanus vaccine by Kenyas health authorities has revealed no traces of the human chorionic gonadotropin hormone.[57]

PDB gallery

1hcn: STRUCTURE OF HUMAN CHORIONIC GONADOTROPIN AT 2.6 ANGSTROMS RESOLUTION FROM MAD ANALYSIS OF THE SELENOMETHIONYL PROTEIN

1hrp: CRYSTAL STRUCTURE OF HUMAN CHORIONIC GONADOTROPIN

1qfw: TERNARY COMPLEX OF HUMAN CHORIONIC GONADOTROPIN WITH FV ANTI ALPHA SUBUNIT AND FV ANTI BETA SUBUNIT

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Human chorionic gonadotropin – Wikipedia

Benefits of HCG Injections for Women | US HCG Injections

Posted: April 28, 2018 at 5:40 am

HCG, Human Chorionic Gonadotropin, is a naturally occurring human hormone that is produced by pregnant females. The hormone originates from the placenta, which is an organ that develops during pregnancy that nourishes the growing baby, providing it with oxygen, nutrients, and other things necessary for healthy growth. The benefits of HCG injections for women are excellent for those looking to lose weight in a healthy, effective way.

As we mentioned earlier, Human Chorionic Gonadotropin is a human hormone that a placenta produces during pregnancy to nourish the mother and child. You may have heard of the many healthful effects of a placenta, and it has become more common for individuals to consume a placenta after birth. It is believed to have a positive, healthy, nourishing effect on the mother that helps her avoid Post-Partum Depression and gives her body a boost. In fact, almost all other mammals consume their placenta after birth, because biology has programmed them to do so. Nature understands the positive effects this act can have for the growth and development, not to mention survival, of a mother, which, in turn, helps her infant as well.

So, what does this have to do with females who are not pregnant? As it turns out, Human Chorionic Gonadotropin is just one of the many beneficial substances produced by the placenta. Scientists have discovered that the hormone has positive effects for those who want to improve their muscle mass or lose weight. The benefits of HCG injections for women cannot be overstated.

The benefits of HCG injections for women are unique to female body chemistry. Yes, men can also take shots of Human Chorionic Gonadotropin, but for females in particular, it has a potent efficacy. Many ladies struggle with stubborn, clinging fat in unwanted areas like the thighs, buttocks, hips, and lower belly. Nature and biology naturally allow fat to accumulate in these areas so as to better prepare a woman for birth and childrearing. However, in our modern day and age, we have less of a need for survival like our modern ancestors did. Natural selection has not quite filtered out the fat accumulation trait, so female bodies still hold onto excess weight as a survival tactic.

Human Chorionic Gonadotropin helps with stubborn weight loss. More often than not, a woman struggles to lose weight in her thighs and buttocks. One of the biggest benefits of HCG injections for women is that it easily allows you to drop pounds. This hormone is miraculous for a number of reasons. First of all, it prevents the feelings of hunger, emptiness, and cravings that cause so many individuals to eat foods that lead to fat and cause them to overeat.

For those who wish to lose weight, saying goodbye to those stubborn pounds can be harder than imagined. For every pound of fat you want to lose, your body needs to be less 3500 calories. While the average adult human needs around 2000 calories a day to maintain a healthy weight, those on diets reduce their caloric intake. This leads to a loss of fat, but in those that take the caloric restriction too far, it can lead to loss of muscle as well. This is considered muscle wasting, and happens when one does not consume a sufficient amount of calories or proteins to reasonably sustain their muscle mass.

Essentially, the individuals body ends up looking emaciated and malnourished. However, one of the benefits of HCG injections for women is that the bodys muscle mass does not atrophy with the deficit of calories. Instead, the Human Chorionic Gonadotropin hormone prevents the bodys metabolism from slowing down or crashing entirely.

The Human Chorionic Gonadotropin diet requires a very low-calorie consumption. Generally, patients consume a high-protein, low carbohydrate, 500-800-calories-per-day diet in conjunction with the shots. Normally, consuming such a low amount of calories would lead to a large number of unwanted side effects such as hunger, a slowed metabolism, headaches, nausea, fainting, and more. However, the hormone shots prevent these side effects from occurring, allowing the low-calorie diet to help you lose weight. The benefits of HCG injections for women prevent the negative side effects from occurring while on the diet. Often, this diet looks like:

Fats should be avoided until you are in phase two of the diet. While in phase one, you should also avoid all fats, butter, oils, and sugars. The diet may seem limited, but it has been carefully crafted and put together in order to help your body easily lose weight in the most effective and healthy manner possible.

Together, the shots and diet lead to effective weight loss that helps individuals lose anywhere from one-half pound to two pounds a day. Most doctors and experts will tell you not to lose more than one pound per week, but that is because they are concerned about the negative side effects, which are avoided thanks to the hormone. So, in this case, the concerns are not applicable. The benefits of HCG injections for women mean you will not have to worry about negative side effects like you would with other diets.

Many people wonder what format is required to receive the full benefits of HCG injections for women. There are many options available, including liquids, gels, pills, sprays, and more. However, if one wants to benefit fully from the hormone, shots are the most effective method. With other methods, the hormone has a chance of dissolving or losing efficacy before reaching the bloodstream. If this happens, you will be wasting your time and efforts, because Human Chorionic Gonadotropin must enter the bloodstream to have the intended positive effects.

It is important to note that the benefits of HCG injections for women generally outweigh any potential side effects that may occur while on the regimen. Thanks to the hormones nurturing and stabilizing properties, you will not suffer from the typical diet side effects such as:

Since the benefits of HCG injections for women also extend to muscle mass and toning, the hormone helps prevent muscle wasting and atrophy. Too often, extremely low-calorie diets lead to lowered metabolisms, caused by the body fearing that starvation is imminent. When this happens, it instead clings to fat and hoards it, afraid that it will need to use the stores to survive. However, Human Chorionic Gonadotropin prevents this from kicking in and allows the fat to flush from your body without unwanted side effects. This means you can still tone and have a healthy looking body muscle mass while still consuming fewer calories and not feeling starved.

In reality, there are very few unwanted side effects of Human Chorionic Gonadotropin shots. Due to the nature of the application, some individuals may experience some initial swelling or redness at the site of the injection, but this will likely subside quickly. Once you begin the routine and your body gets used to the shots, the redness should dissipate, and you should start to see the benefits of HCG injections for women.

If you are someone who is not sure about using a syringe and injecting yourself every day, you are not alone. Plenty of people have been hesitant about this procedure, but when you think about it, it is no different from a person with diabetes injecting him or herself with insulin every day or someone using an epi-pen. Once you get the hang of it, you will not even have to think twice about it. In the end, the benefits of HCG injections for women are more than worth it to lose the stubborn, clinging fat that just will not go away.

To help you prepare and to receive the benefits of HCG injections for women, we make sure that you have all of the information and supplies that you will need. Each kit comes standard with:

These materials will prepare you with everything you may need for the shots and to reap the benefits of HCG injections for women.

On any diet, you should be sure to seek out the supervision of a trusted medical professional. Because Human Chorionic Gonadotropin shots are only available on a prescription basis, you will need to establish care with a practitioner. Once you have the prescription, you can fulfill it through US HCG Shots, getting you the best deal. If you come across options that are homeopathic or over-the-counter, you should avoid them. Human Chorionic Gonadotropin is only effective when it is prescription strength, and other products and formulas that are not prescription may be of a much lower quality. To get the most effective product and to get the benefits of HCG injections for women, trust US HCG Shots.

As a female seeking the benefits of HCG injections for women, you should be aware that, because HCG is the primary hormone used by pregnancy tests to detect pregnancy, your regimen of shots could lead to a false positive on a pregnancy test. If you are or may become pregnant, you should not take Human Chorionic Gonadotropin shots. While the hormone is naturally present in pregnant females, taking extra hormones can cause an increase that goes beyond what is optimal for weight loss. Lactating and breastfeeding mothers should also not take these shots as they can be transferred through breastmilk, and the amount may be harmful to the infant.

When it comes to losing weight, we understand how difficult it can be. For too long, people have resorted to drastic measures in hopes of losing a few pounds and reaching a healthy body weight. Paired with a very low-calorie diet, the benefits of HCG injections for women are far-reaching for those who want to lose weight. With the hormone, you can lose anywhere from 0.5 to 1 pound per day in a healthy, natural way. Even though the weight loss will be rapid, the hormones properties will prevent the body from wasting or sagging, as you may have seen with other dramatic weight loss procedures.

A diet based on the reduced calories combined with the consumption of Human Chorionic Gonadotropin is not a new concept. The Human Chorionic Gonadotropin diet was pioneered by Dr. Albert T. W. Simeons, a British endocrinologist, in the 1950s. Dr. Simeons spent a great deal of time studying obesity patients and published a book titled Pounds and Inches. This book outlines a plan for losing weight quickly on a VLCD (Very Low Calorie Diet). Other doctors have reviewed his work and also support his findings. Largely, this is due to further research on the hormone and the benefits of HCG injections for women.

Hormones play a large role in how womens weight is distributed. This is especially true for fat distribution. Hormones also have the ability to alter the fat stored in the body dramatically. This is why Human Chorionic Gonadotropin is so powerful for losing weight, thanks to the benefits of HCG injections for women. The hormone prevents the bodys metabolism from crashing and continues long after the hormone shot therapy has ended. By altering the messages that the brain receives with the help of the hormone, your body will stabilize. This means that the loss of fat will continue, even though the muscle tone will remain.

Losing weight can be hard. Hundreds, thousands, and millions of people struggle with their weight on a daily basis, and obesity has become a rampant problem in the modern world. Excess weight is one of the leading causes of other health issues, such as:

To participate in the benefits of HCG injections for women, call US HCG Shots today at 1-855-862-9510 Monday Friday from 9:00 am 5:00 pm EST.

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Benefits of HCG Injections for Women | US HCG Injections


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